Phenobarbital

C-C motif chemokine ligand 4 ; Rattus norvegicus







57 Article(s)
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1 12949661 Effects of homeopathic preparations on the liver in rats with acute and chronic toxic hepatitis. 2003 Jan 1
2 9927535 Phenobarbital in comparison with carbon tetrachloride and phenobarbital-induced cirrhosis in rat liver regeneration. 1999 Feb 1
3 9357164 Differential biochemical response of freshly isolated rat hepatocytes to paracetamol, carbon tetrachloride and D-galactosamine toxicity. 1997 Jun 1
4 8627517 Molecular mechanism for alkyl sulfide-modulated carbon tetrachloride-induced hepatotoxicity: the role of cytochrome P450 2E1, P450 2B and glutathione S-transferase expression. 1996 May 1
5 7535226 Amplified interactive toxicity of chemicals at nontoxic levels: mechanistic considerations and implications to public health. 1994 Nov 1
6 7817119 Effect of phenobarbital and mirex pretreatments on CCl4 autoprotection. 1994 May-Jun 1
7 1284994 Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats. 1992 3
8 1354082 Possible enhancing effect of the immunosuppressive agent, 6-mercaptopurine(6-MP) on focal lesion development in cirrhotic liver induced by carbon tetrachloride but not furfural in F344 rats. 1992 Aug 2
9 1469101 Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. 1992 Dec 2
10 1530140 Effects of ethanol and carbon tetrachloride upon vitamin A status of rats. 1992 Aug 2
11 1568734 Opposite responses of nuclear spermidine N8-acetyltransferase and histone acetyltransferase activities to regenerative stimuli in rat liver. 1992 May 1
12 1733051 Further examination of the selective toxicity of CCl4 in rat liver slices. 1992 Jan 1
13 1780643 Liver damaging effect of suramin in normal and carbon-tetrachloride treated rats. 1991 1
14 1839629 Relationship between oxidative stress and hepatic phosphoglucomutase activity in rats. 1991 1
15 1921373 Liver cirrhosis in rats: regeneration and assessment of the role of phenobarbital. 1991 Oct 2
16 1696756 Lethal effects of CCl4 and its metabolism by Mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex. 1990 Jul 2
17 1696822 Altered hepatic energy status in chlordecone (Kepone)-potentiated CCl4 hepatotoxicity. 1990 Aug 15 1
18 2222449 Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. 1990 Sep 28 1
19 2315927 Phenobarbital pretreatment alters the localization of CCl4-induced changes in rat liver microsomal fatty acids. 1990 Mar 15 4
20 2390286 Microsomal metabolism of carbon tetrachloride: participation of pyridine nucleotide synergism. 1990 Aug 2
21 2749135 Reversibility of rat liver cirrhosis by medroxyprogesterone acetate. 1989 1
22 2451866 In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital. 1988 Apr 2
23 2832723 The carbon dioxide anion radical adduct in the perfused rat liver: relationship to halocarbon-induced toxicity. 1988 Mar 1
24 2907458 In vivo radical trapping and biliary secretion of radical adducts of carbon tetrachloride-derived free radical metabolites. 1988 Nov-Dec 1
25 3127945 Detection of CCl4-induced oxidation of hepatic tissue in vivo by oxygen-18 tracing. 1988 Mar 30 1
26 3377780 Inhibition of CCl4 metabolism by oxygen varies between isoenzymes of cytochrome P-450. 1988 May 16 2
27 3401014 Lipid peroxidation and cell viability in isolated hepatocytes in a redesigned oxystat system: evaluation of the hypothesis that lipid peroxidation, preferentially induced at low oxygen partial pressures, is decisive for CCl4 liver cell injury. 1988 Aug 1 1
28 3420613 The role of CCl4 biotransformation in the activation of hepatocyte phospholipase C in vivo and in vitro. 1988 Sep 15 1
29 2435023 Comparative changes in hepatic DNA, RNA, protein, lipid, and glycogen induced by a subtoxic dose of CCl4 in chlordecone, mirex, and phenobarbital pretreated rats. 1987 Feb 1
30 3007463 The formation of a novel free radical metabolite from CCl4 in the perfused rat liver and in vivo. 1986 Apr 5 1
31 3095627 Evidence for increased membrane permeability of plasmalemmal vesicles from livers of phenobarbital-induced CCl4-intoxicated rats. 1986 Nov 2
32 3707616 Changes in cytochrome P450 molecular species in rat liver in chloroform intoxication. 1986 May 1 1
33 3775859 [Detection of cells resistant to the cytotoxic action of CCl4 in rat hepatocyte populations following a single exposure to diethylnitrosamine and subsequent injections of phenobarbital]. 1986 Aug 1
34 3942013 Effect of pretreatment with cimetidine or phenobarbital on lipoperoxidation in carbon tetrachloride- and trichloroethylene-dosed rats. 1986 Jan 2
35 3947068 Carbon tetrachloride and 2-isopropyl-4-pentenamide-induced inactivation of cytochrome P-450 leads to heme-derived protein adducts. 1986 Jan 1
36 2864416 Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone. 1985 Aug 3
37 3937306 [Detection of cells resistant to the cytotoxic action of CCl4 in the hepatocyte populations of rats following a single exposure to 4-dimethylaminoazobenzene combined with subsequent injections of the tumor promoter phenobarbital]. 1985 Nov 1
38 6099695 Carbon tetrachloride activation by highly purified liver mitochondrial preparations. 1984 Dec 1
39 6101050 [Effect of phenobarbital on the morphologic, histochemical and ultrastructural picture of the rat liver after chronic administration of CCl4]. 1984 1
40 6206609 CCl4-hepatotoxicity in the Mongolian gerbil: influence of monooxygenase system induction. 1984 Aug 2
41 6209127 Perturbation of calcium homeostasis by CCl4 in rats pretreated with chlordecone and phenobarbital. 1984 Aug 3
42 6700577 Reductive-oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P-450. 1984 Mar 1
43 6193935 Hepatic microsomal metabolism of CCL4 after pretreatment with chlordecone, mirex, or phenobarbital in male rats. 1983 Jul-Aug 1
44 6196592 Destruction of hepatic mixed-function oxygenase parameters by CCl4 in rats following acute treatment with chlordecone, Mirex, and phenobarbital. 1983 Dec 5 2
45 6114833 The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride. 1981 Jul-Aug 2
46 7294161 Dependence of the carbon-tetrachloride--induced death of cultured hepatocytes on the extracellular calcium concentration. 1981 Nov 1
47 18792759 Effect of phenobarbital on hepatic injury induced by chronic carbon tetrachloride treatment. 1981 Oct 3
48 6259312 Comparative studies on the hepatotoxic actions of chloroform and related halogenomethanes in normal and phenobarbital-pretreated animals. 1980 Jan 1
49 6767337 Differences in the response of hepatic and intestinal drug metabolizing enzymes in rats following carbon tetrachloride and/or phenobarbital treatment. 1980 Jan 1
50 695749 Effect of phenobarbitone and propionyl-promazine on serum enzymes in carbon-tetrachloride hepatotoxicity. 1978 Sep 3