| 51 |
20067614 | Smoothened as a new therapeutic target for human osteosarcoma. | 2010 Jan 12 |
2 |
| 52 |
20451654 | Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling. | 2010 Sep |
1 |
| 53 |
20840857 | Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia. | 2010 Dec |
1 |
| 54 |
21154121 | Agents targeting the Hedgehog pathway for pancreatic cancer treatment. | 2010 Dec |
2 |
| 55 |
18563554 | Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). | 2009 Jun |
2 |
| 56 |
19196978 | Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. | 2009 Feb 24 |
1 |
| 57 |
19232458 | Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer. | 2009 Oct 8 |
1 |
| 58 |
19365551 | Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium. | 2009 |
2 |
| 59 |
16867986 | Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells. | 2006 Sep 29 |
1 |
| 60 |
16136078 | Vertebrate Smoothened functions at the primary cilium. | 2005 Oct 13 |
1 |
| 61 |
15618519 | Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. | 2004 Dec 24 |
3 |
| 62 |
12679031 | The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. | 2003 Apr 4 |
4 |
| 63 |
11965540 | Introduction of wild-type patched gene suppresses the oncogenic potential of human squamous cell carcinoma cell lines including A431. | 2002 Apr 18 |
1 |
| 64 |
12391318 | Small molecule modulation of Smoothened activity. | 2002 Oct 29 |
2 |
| 65 |
12414725 | Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. | 2002 Nov 1 |
5 |
| 66 |
10984056 | Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. | 2000 Aug 31 |
2 |