| 1 |
35521940 | Expression of the hedgehog signalling pathway and the effect of inhibition at the level of smoothened in canine osteosarcoma cell lines. | 2022 May 6 |
2 |
| 2 |
34439999 | Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration. | 2021 Aug 12 |
2 |
| 3 |
34755677 | [G-protein coupled receptor Smo positively regulates proliferation and migration of adult neural stem cells in vitro]. | 2021 Oct 20 |
2 |
| 4 |
31707356 | A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine. | 2020 Jan |
3 |
| 5 |
32383186 | Oncogenic properties and signaling basis of the PAX8-GLIS3 fusion gene. | 2020 Oct 15 |
2 |
| 6 |
33080820 | Inhibition of Melanoma Cell Migration and Invasion Targeting the Hypoxic Tumor Associated CAXII. | 2020 Oct 17 |
2 |
| 7 |
30582981 | The long non-coding RNA LncHDAC2 drives the self-renewal of liver cancer stem cells via activation of Hedgehog signaling. | 2019 May |
1 |
| 8 |
30638689 | Promotion of osteogenesis by bioactive glass-ceramic coating: Possible involvement of the Hedgehog signaling pathway. | 2019 Jul |
3 |
| 9 |
30644322 | Targeting the cross-talk between the hedgehog and NF-κB signaling pathways in multiple myeloma. | 2019 Mar |
1 |
| 10 |
31018557 | Clobetasol Modulates Adult Neural Stem Cell Growth via Canonical Hedgehog Pathway Activation. | 2019 Apr 23 |
1 |
| 11 |
28849750 | Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein. | 2018 Aug |
1 |
| 12 |
29115520 | CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway. | 2018 Jan |
2 |
| 13 |
30568656 | Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway. | 2018 |
1 |
| 14 |
28112475 | Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis. | 2017 Feb |
1 |
| 15 |
28458545 | Role of Hedgehog-Gli1 signaling in the enhanced proliferation and differentiation of MG63 cells enabled by hierarchical micro-/nanotextured topography. | 2017 |
1 |
| 16 |
28591579 | Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation. | 2017 Jun 6 |
2 |
| 17 |
28957797 | Resveratrol Enhances Neurite Outgrowth and Synaptogenesis Via Sonic Hedgehog Signaling Following Oxygen-Glucose Deprivation/Reoxygenation Injury. | 2017 |
1 |
| 18 |
26902390 | Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis. | 2016 Feb 23 |
3 |
| 19 |
27639396 | Role of Sonic Hedgehog Signaling in Oligodendrocyte Differentiation. | 2016 Dec |
2 |
| 20 |
27678330 | Cross-talk between Human Papillomavirus Oncoproteins and Hedgehog Signaling Synergistically Promotes Stemness in Cervical Cancer Cells. | 2016 Sep 28 |
1 |
| 21 |
27736063 | Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists. | 2016 Dec 22 |
1 |
| 22 |
27752995 | Hedgehog/Gli1 signal pathway facilitates proliferation, invasion, and migration of cutaneous SCC through regulating VEGF. | 2016 Oct 17 |
1 |
| 23 |
25595187 | Modulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells. | 2015 Mar |
2 |
| 24 |
25716561 | Autophagy Accompanied with Bisdemethoxycurcumin-induced Apoptosis in Non-small Cell Lung Cancer Cells. | 2015 Feb |
1 |
| 25 |
25750281 | Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth. | 2015 Mar |
2 |
| 26 |
24291104 | Inhibition mechanism exploration of investigational drug TAK-441 as inhibitor against Vismodegib-resistant Smoothened mutant. | 2014 Jan 15 |
1 |
| 27 |
24394624 | Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. | 2014 Jun |
1 |
| 28 |
24741597 | Sonic hedgehog signaling drives proliferation of synoviocytes in rheumatoid arthritis: a possible novel therapeutic target. | 2014 |
2 |
| 29 |
23448715 | Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened. | 2013 May |
1 |
| 30 |
23483902 | Gli as a novel therapeutic target in malignant pleural mesothelioma. | 2013 |
1 |
| 31 |
23508962 | Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to Smoothened-targeting Hedgehog inhibition. | 2013 Apr 26 |
1 |
| 32 |
23786654 | Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner. | 2013 Jun 20 |
3 |
| 33 |
23954590 | Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. | 2013 Aug 26 |
1 |
| 34 |
24250231 | The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells. | 2013 |
1 |
| 35 |
22204396 | Pharmacological modulation of the Hedgehog pathway differentially affects dorsal/ventral patterning in mouse and human embryonic stem cell models of telencephalic development. | 2012 May 1 |
2 |
| 36 |
22409914 | Advances in Smoothened-targeting therapies for pancreatic cancer: implication for drug discovery from herbal medicines. | 2012 Mar |
2 |
| 37 |
22428030 | The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells. | 2012 |
1 |
| 38 |
22450749 | SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway. | 2012 Sep 28 |
2 |
| 39 |
22500124 | Hedgehog pathway as a drug target: Smoothened inhibitors in development. | 2012 |
1 |
| 40 |
22679015 | Targeting the sonic hedgehog pathway in keratocystic odontogenic tumor. | 2012 Aug 3 |
1 |
| 41 |
22730244 | Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells. | 2012 Sep |
2 |
| 42 |
22849868 | Integrated QSAR study for inhibitors of Hedgehog Signal Pathway against multiple cell lines:a collaborative filtering method. | 2012 Jul 31 |
1 |
| 43 |
23063129 | Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat. | 2012 Oct 12 |
1 |
| 44 |
21135115 | Hedgehog signaling drives cellular survival in human colon carcinoma cells. | 2011 Feb 1 |
1 |
| 45 |
21177415 | Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist. | 2011 Mar |
1 |
| 46 |
21630164 | Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines. | 2011 |
1 |
| 47 |
21674124 | Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth. | 2011 Oct |
1 |
| 48 |
21718593 | Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling. | 2011 Jul |
4 |
| 49 |
22038837 | Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells. | 2011 Dec |
2 |
| 50 |
20024066 | Small-molecule modulators of the Sonic Hedgehog signaling pathway. | 2010 Jan |
1 |