Phosphatidylinositol 4,5-Diphosphate

prolactin induced protein ; Homo sapiens







82 Article(s)
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1 23530136 Two structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides. 2013 Apr 3
2 21876211 The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. 2012 Jan 2
3 22403073 PIP kinases from the cell membrane to the nucleus. 2012 1
4 22475207 Synergistic effect of Pb(2+) and phosphatidylinositol 4,5-bisphosphate on C2 domain-membrane interactions. 2012 Apr 24 1
5 22595022 Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix. 2012 Jul 1
6 22609963 Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphate. 2012 Sep 1
7 22613714 The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site. 2012 Jul 13 1
8 22891352 PIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker. 2012 Sep 4 1
9 22950482 Phosphatidylinositol 4,5-biphosphate (PIP(2)) lipids regulate the phosphorylation of syntaxin N-terminus by modulating both its position and local structure. 2012 Oct 2 1
10 23055973 Dual Regulation of Voltage-Sensitive Ion Channels by PIP(2). 2012 1
11 21051544 Combined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels. 2011 Jan 7 1
12 21097841 The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells. 2011 Jan 21 1
13 21107857 Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. 2011 Mar 1
14 21156029 Ion channel activity of brain abundant protein BASP1 in planar lipid bilayers. 2011 Feb 1
15 21158426 A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes. 2011 Mar 18 1
16 21281576 Dual-mode phospholipid regulation of human inward rectifying potassium channels. 2011 Feb 2 1
17 21576493 KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity. 2011 May 31 1
18 21654216 ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. 2011 Jul-Aug 1
19 21795401 Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. 2011 Sep 2
20 21826776 Effect of PIP2 on bilayer structure and phase behavior of DOPC: an X-ray scattering study. 2011 Oct 4 1
21 21874019 Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2. 2011 Aug 28 1
22 19934648 PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions. 2010 Jan-Feb 1
23 19948740 AIP1 functions as Arf6-GAP to negatively regulate TLR4 signaling. 2010 Feb 5 1
24 20338845 A molecular dynamics investigation of lipid bilayer perturbation by PIP2. 2010 Jan 20 1
25 20472831 Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells. 2010 Aug 26 1
26 20472984 Tamoxifen inhibits cardiac ATP-sensitive and acetylcholine-activated K+ currents in part by interfering with phosphatidylinositol 4,5-bisphosphate-channel interaction. 2010 1
27 20670831 Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate. 2010 Jul 29 1
28 20729206 m-Calpain activation is regulated by its membrane localization and by its binding to phosphatidylinositol 4,5-bisphosphate. 2010 Oct 22 1
29 21219032 Characterization of supported lipid bilayers incorporating the phosphoinositides phosphatidylinositol 4,5-biphosphate and phosphoinositol-3,4,5-triphosphate by complementary techniques. 2010 Dec 1
30 19036880 Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin. 2009 Apr 1
31 19172411 Abnormal bradykinin signalling in fibroblasts deficient in the PIP(2) 5-phosphatase, ocrl1. 2009 Apr 1
32 19332618 Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels. 2009 Apr 1
33 19509404 Finding partners for PI3Kgamma: when 84 is better than 101. 2009 Jun 9 1
34 19639958 High affinity binding to profilin by a covalently constrained, soluble mimic of phosphatidylinositol-4,5-bisphosphate micelles. 2009 Sep 18 1
35 19729450 Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate. 2009 Oct 23 1
36 19808673 Differential effects of lysophosphatidic acid and phosphatidylinositol 4,5-bisphosphate on actin dynamics by direct association with the actin-binding protein villin. 2009 Dec 18 1
37 18341295 Interactions of the pleckstrin homology domain with phosphatidylinositol phosphate and membranes: characterization via molecular dynamics simulations. 2008 Apr 8 1
38 18562499 Direct regulation of BK channels by phosphatidylinositol 4,5-bisphosphate as a novel signaling pathway. 2008 Jul 1
39 18572937 Combined electrostatics and hydrogen bonding determine intermolecular interactions between polyphosphoinositides. 2008 Jul 16 1
40 18610985 Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. 2008 Aug 12 1
41 18758068 Involvement of phosphatidylinositol 4,5-bisphosphate in the desensitization of canonical transient receptor potential 5. 2008 Sep 1
42 18923421 EFC/F-BAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization. 2008 Nov 5 1
43 19956793 Spatial Segregation of Phosphatidylinositol 4,5-Bisphosphate (PIP(2)) Signaling in Immune Cell Functions. 2008 Dec 1 2
44 17031667 Regulation of TRP channels by PIP(2). 2007 Mar 1
45 17074062 Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate. 2007 Jan 1
46 17182619 Structure/function analysis of the interaction of phosphatidylinositol 4,5-bisphosphate with actin-capping protein: implications for how capping protein binds the actin filament. 2007 Feb 23 1
47 17233611 TRPC1: a core component of store-operated calcium channels. 2007 Feb 1
48 17395626 Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. 2007 Aug 1 3
49 17412762 Target-specific PIP(2) signalling: how might it work? 2007 Aug 1 1
50 17520274 Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases. 2007 Oct 1