lysophosphatidic acid

ectonucleotide pyrophosphatase/phosphodiesterase 2 ; Mus musculus







113 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 27516465 Pharmacological Characterization of a Potent Inhibitor of Autotaxin in Animal Models of Inflammatory Bowel Disease and Multiple Sclerosis. 2016 Oct 2
52 25596343 Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis. 2015 May 3
53 25646365 Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis. 2015 Apr 1
54 25669348 Carbamoylphosphonates inhibit autotaxin and metastasis formation in vivo. 2015 1
55 25769037 Decreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1. 2015 1
56 25992708 Autotaxin overexpression causes embryonic lethality and vascular defects. 2015 5
57 26196781 Autotaxin and Endotoxin-Induced Acute Lung Injury. 2015 6
58 26224810 Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve. 2015 Aug 25 2
59 26345369 LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells. 2015 Nov 1 4
60 26569406 The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life. 2015 3
61 23639740 Involvement of autotaxin/lysophosphatidic acid signaling in obesity and impaired glucose homeostasis. 2014 Jan 5
62 24120919 Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence. 2014 Jan 2
63 24504738 Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. 2014 Apr 1
64 24641902 Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. 2014 May 1
65 25053164 Autotaxin downregulates LPS-induced microglia activation and pro-inflammatory cytokines production. 2014 Dec 4
66 23022664 Autotaxin in embryonic development. 2013 Jan 4
67 23063960 Decrease in circulating autotaxin by oral administration of prednisolone. 2013 Jan 16 8
68 23793291 Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface. 2013 Sep 4
69 23948545 Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. 2013 Oct 2
70 24050723 Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. 2013 Oct 15 6
71 24175745 Development of lysophosphatidic acid pathway modulators as therapies for fibrosis. 2013 Oct 2
72 24278115 Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate. 2013 5
73 22015657 Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. 2012 Jan 2
74 22155714 Autotaxin protects microglial cells against oxidative stress. 2012 Jan 15 4
75 22474126 Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. 2012 May 2
76 22744859 Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis. 2012 Nov 3
77 22962684 Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. 2012 Oct 15 6
78 21240269 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators. 2011 Feb 6
79 21421848 Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid. 2011 Jun 6
80 21465666 Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity. 2011 May 2 2
81 21531341 Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium. 2011 May 4 2
82 21542849 Pre-emptive morphine treatment abolishes nerve injury-induced lysophospholipid synthesis in mass spectrometrical analysis. 2011 Jul 3
83 21569544 Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain. 2011 May 14 1
84 21696367 Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways. 2011 Oct 1 6
85 20079728 ATX expression and LPA signalling are vital for the development of the nervous system. 2010 Mar 15 2
86 20123931 Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain. 2010 May 10
87 20231358 Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression. 2010 May 4
88 20305819 Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts. 2010 Mar 17 7
89 20360563 Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. 2010 Apr 20 6
90 20417246 Biological roles of lysophosphatidic acid signaling through its production by autotaxin. 2010 Jun 5
91 20692235 Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway. 2010 Sep 10 4
92 19139100 Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. 2009 Mar 13 14
93 19184538 Lysophosphatidic acid and autotaxin: emerging roles in innate and adaptive immunity. 2009 Dec 2
94 19416959 Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood. 2009 Aug 2
95 19477432 Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. 2009 Jun 2 1
96 19482419 Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells. 2009 Nov 1 1
97 19509223 Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo. 2009 Jul 1 1
98 19808661 Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac. 2009 Nov 27 4
99 19912636 Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain. 2009 Nov 13 5
100 18261210 Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain. 2008 Feb 8 5