| 1 |
33801950 | Bioinformatic Analysis of the Nicotinamide Binding Site in Poly(ADP-Ribose) Polymerase Family Proteins. | 2021 Mar 10 |
1 |
| 2 |
34587882 | Poly(ADP-Ribose) Polymerase-1 Inhibitors Drug Discovery, Design, and Development as Anticancer Agents from Past to Present: A Mini-Review. | 2021 Sep 29 |
2 |
| 3 |
34845199 | Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells. | 2021 Nov 29 |
1 |
| 4 |
32788029 | [Progress of nicotinamide in preventing infection and sepsis]. | 2020 Jul |
2 |
| 5 |
32903806 | Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease. | 2020 |
7 |
| 6 |
30912451 | Advances in the use of PARP inhibitors for BRCA1/2-associated breast cancer: talazoparib. | 2019 May |
3 |
| 7 |
31257855 | Quartz Crystal Microbalance Detection of Poly(ADP-ribose) Polymerase-1 Based on Gold Nanorods Signal Amplification. | 2019 Sep 3 |
1 |
| 8 |
31308445 | Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation. | 2019 Jul 15 |
3 |
| 9 |
29968072 | Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders. | 2018 Dec |
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| 10 |
27990620 | Role of Peroxynitrite-Induced Activation of Poly(ADP-Ribose) Polymerase (PARP) in Circulatory Shock and Related Pathological Conditions. | 2017 Oct |
2 |
| 11 |
28695516 | Strategies Employed for the Development of PARP Inhibitors. | 2017 |
2 |
| 12 |
26518726 | Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres. | 2016 Mar |
4 |
| 13 |
26709902 | Alternative mechanisms of inhibiting activity of poly (ADP-ribose) polymerase-1. | 2016 Jan 1 |
2 |
| 14 |
27193581 | Latonduine Analogs Restore F508del-Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity. | 2016 Aug |
1 |
| 15 |
25504347 | Nicotinamide sensitizes human breast cancer cells to the cytotoxic effects of radiation and cisplatin. | 2015 Feb |
1 |
| 16 |
26387143 | Negative prognostic value of high levels of intracellular poly(ADP-ribose) in non-small cell lung cancer. | 2015 Dec |
2 |
| 17 |
26788021 | Pathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP). | 2015 Oct |
2 |
| 18 |
24635573 | Nicotinamide and the skin. | 2014 Aug |
2 |
| 19 |
24641686 | Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets. | 2014 Apr 9 |
1 |
| 20 |
24993939 | Niacinamide - mechanisms of action and its topical use in dermatology. | 2014 |
2 |
| 21 |
23290998 | Poly(ADP-ribose): PARadigms and PARadoxes. | 2013 Dec |
1 |
| 22 |
23454167 | NAD(+) influx through connexin hemichannels prevents poly(ADP-ribose) polymerase-mediated astrocyte death. | 2013 Apr 19 |
1 |
| 23 |
23879431 | Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases. | 2013 Sep 12 |
1 |
| 24 |
22204321 | NAD+ metabolism and NAD(+)-dependent enzymes: promising therapeutic targets for neurological diseases. | 2012 Feb |
1 |
| 25 |
22233320 | Structural basis of selective inhibition of human tankyrases. | 2012 Feb 9 |
1 |
| 26 |
22293058 | Intrinsic radiation resistance of mesenchymal cancer stem cells and implications for treatment response in a murine sarcoma model. | 2012 Feb |
1 |
| 27 |
22297980 | Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939. | 2012 Feb 1 |
1 |
| 28 |
22365563 | Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors. | 2012 Apr |
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| 29 |
22465780 | Nicotinamide treatment reduces the levels of histone H3K4 trimethylation in the promoter of the mper1 circadian clock gene and blocks the ability of dexamethasone to induce the acute response. | 2012 Aug |
1 |
| 30 |
22476980 | Natural inhibitors of poly(ADP-ribose) polymerase-1. | 2012 Aug |
1 |
| 31 |
21825006 | Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft. | 2011 Oct |
1 |
| 32 |
21870251 | Approaches to detect PARP-1 activation in vivo, in situ, and in vitro. | 2011 |
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| 33 |
21870278 | Strategies employed for the development of PARP inhibitors. | 2011 |
2 |
| 34 |
20005237 | Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy. | 2010 Mar |
1 |
| 35 |
20633699 | Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications. | 2010 Sep-Oct |
1 |
| 36 |
20725615 | Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. | 2010 Jul 25 |
2 |
| 37 |
20804590 | Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide. | 2010 Aug 24 |
1 |
| 38 |
19127080 | Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. | 2009 |
1 |
| 39 |
18199640 | Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: involvement of host cellular factors. | 2008 Mar |
1 |
| 40 |
18230337 | p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells. | 2008 Apr 4 |
2 |
| 41 |
18600553 | Cytoprotective effects of nicotinamide derivatives in endothelial cells. | 2008 Jun |
2 |
| 42 |
17504138 | Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation. | 2007 |
1 |
| 43 |
17520094 | Poly(ADP-ribose) polymerase as a drug target for cardiovascular disease and cancer: an update. | 2007 Apr |
2 |
| 44 |
16505238 | MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells. | 2006 Mar |
1 |
| 45 |
16604373 | Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. | 2006 Jun |
3 |
| 46 |
16611073 | Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide. | 2006 |
1 |
| 47 |
16631419 | Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes. | 2006 May |
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| 48 |
17384246 | Molecular determinants involved in the increase of damage-induced apoptosis and delay of secondary necrosis due to inhibition of mono(ADP-ribosyl)ation. | 2006 Dec |
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| 49 |
20021043 | Nicotinamide prevents apoptosis in human cortical neuronal cells. | 2006 |
2 |
| 50 |
15857303 | Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma. | 2005 Apr |
2 |