Calcitriol

cytochrome P450 family 24 subfamily A member 1 ; Homo sapiens







128 Article(s)
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1 34003583 The ERRα-VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR-CYP24A1-ERRα overexpression correlates with poor prognosis in patients with basal-like breast cancer. 2022 Feb 1
2 35179903 Codelivery of 1α,25-Dihydroxyvitamin D3 and CYP24A1 Inhibitor VID400 by Nanofiber Dressings Promotes Endogenous Antimicrobial Peptide LL-37 Induction. 2022 Mar 7 1
3 35482362 Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule. 2022 Apr 28 4
4 33791222 Micro1278 Leads to Tumor Growth Arrest, Enhanced Sensitivity to Oxaliplatin and Vitamin D and Inhibits Metastasis via KIF5B, CYP24A1, and BTG2, Respectively. 2021 1
5 33895119 Inhibition of calcitriol inactivating enzyme CYP24A1 gene expression by flavonoids in hepatocellular carcinoma cells under normoxia and hypoxia. 2021 Jun 15 4
6 34093587 Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets. 2021 1
7 34307984 High Prevalence of Kidney Cysts in Patients With CYP24A1 Deficiency. 2021 Jul 1
8 34337279 24-Hydroxylase Deficiency Due to CYP24A1 Sequence Variants: Comparison With Other Vitamin D-mediated Hypercalcemia Disorders. 2021 Sep 1 2
9 34389675 Drivers and suppressors of triple-negative breast cancer. 2021 Aug 17 1
10 34593422 Inhibition of CYP27B1 and CYP24 Increases the Anti-proliferative Effects of 25-Hydroxyvitamin D3 in LNCaP Cells. 2021 Oct 2
11 34662328 Hypercalcemia and CYP24A1 Gene Mutation Diagnosed in the 2nd Trimester of a Twin Pregnancy: A Case Report. 2021 Oct 18 2
12 34980721 Transcriptional Regulation of 25-Hydroxyvitamin D-24-Hydroxylase (CYP24A1) by Calcemic Factors in Keratinocytes. 2021 1
13 31704333 Synthesis and biological evaluation of calcioic acid. 2020 Feb 1
14 31789978 Inherited conditions resulting in nephrolithiasis. 2020 Apr 1
15 32259445 Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1. 2020 Apr 21 2
16 33329593 Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis. 2020 1
17 30729229 Three Sisters With Heterozygous Gene Variants of CYP24A1: Maternal Hypercalcemia, New-Onset Hypertension, and Neonatal Hypoglycemia. 2019 Feb 1 1
18 31471674 The Effect of Caffeine on Calcitriol-Inducible Vitamin D Receptor-Controlled Gene Expression in Intestinal and Osteoblastic Cells. 2019 Dec 1
19 31638226 Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line. 2019 Dec 4
20 29489902 Effects of human interleukins in the transgenic gene reporter cell lines IZ-VDRE and IZ-CYP24 designed to assess the transcriptional activity of vitamin D receptor. 2018 1
21 30052060 CYP24A1 Inhibition Facilitates the Antiproliferative Effect of 1,25(OH)2D3 Through Downregulation of the WNT/β-Catenin Pathway and Methylation-Mediated Regulation of CYP24A1 in Colorectal Cancer Cells. 2018 Sep 6
22 30326825 Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production. 2018 Oct 16 1
23 28218743 Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management. 2017 Jun 1
24 28242615 Cyp24a1 Attenuation Limits Progression of BrafV600E -Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720. 2017 Apr 15 1
25 28324001 CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations. 2017 May 1 1
26 28578001 1α,25-Dihydroxyvitamin D3 enhances TRPV6 transcription through p38 MAPK activation and GADD45 expression. 2017 Sep 1
27 28601511 Synthesis, molecular modelling and CYP24A1 inhibitory activity of novel of (E)-N-(2-(1H-imidazol-1-yl)-2-(phenylethyl)-3/4-styrylbenzamides. 2017 Aug 1 1
28 29080636 Genetic Diseases of Vitamin D Metabolizing Enzymes. 2017 Dec 1
29 29127362 Functional Analysis of VDR Gene Mutation R343H in A Child with Vitamin D-Resistant Rickets with Alopecia. 2017 Nov 10 1
30 26047794 Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia. 2016 Feb 1
31 26729468 Loss of miR-125b contributes to upregulation of CYP24 in uraemic rats. 2016 Dec 2
32 26794222 1,25-dihydroxyvitamin D3 inhibits corneal wound healing in an ex-vivo mouse model. 2016 Apr 1
33 26827951 25-Hydroxyvitamin D₃ 24-Hydroxylase: A Key Regulator of 1,25(OH)₂D₃ Catabolism and Calcium Homeostasis. 2016 1
34 26827958 Vitamin D in Prostate Cancer. 2016 1
35 27195054 TNF-α increases the expression and activity of vitamin D receptor in keratinocytes: role of c-Jun N-terminal kinase. 2016 Jan-Dec 1
36 27210415 Evidence of sexual dimorphism in placental vitamin D metabolism: Testosterone inhibits calcitriol-dependent cathelicidin expression. 2016 Oct 1
37 27530414 Vitamin D machinery and metabolism in porcine adipose-derived mesenchymal stem cells. 2016 Aug 17 1
38 27769055 Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1. 2016 Nov 22 7
39 27889974 [Vitamin D metabolism and signaling in human hepatocellular carcinoma and surrounding non-tumorous liver]. 2016 Nov 2
40 25584965 Regulation of calcitriol biosynthesis and activity: focus on gestational vitamin D deficiency and adverse pregnancy outcomes. 2015 Jan 9 1
41 25639477 Vitamin D₃ metabolites enhance the NLRP3-dependent secretion of IL-1β from human THP-1 monocytic cells. 2015 May 1
42 25716812 [Current Topics on Vitamin D. Protein interaction and biological action of active vitamin D compounds]. 2015 Mar 1
43 25727742 Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1. 2015 May 1
44 25866638 TSLP is differentially regulated by vitamin D3 and cytokines in human skin. 2015 Mar 1
45 26097993 Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. 2015 Aug 1
46 24120915 Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells. 2014 Oct 1
47 24235083 Chronic hypercalcaemia from inactivating mutations of vitamin D 24-hydroxylase (CYP24A1): implications for mineral metabolism changes in chronic renal failure. 2014 Mar 1
48 24361583 Regulation of CYP27B1 and CYP24A1 gene expression by recombinant pro-inflammatory cytokines in cultured human trophoblasts. 2014 Oct 2
49 24572979 Importance of dietary calcium and vitamin D in the treatment of hypercalcaemia in Williams-Beuren syndrome. 2014 Jul 1
50 24736069 Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma. 2014 Apr 2