Arsenic Trioxide

BCL2 apoptosis regulator ; Homo sapiens







93 Article(s)
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51 20723295 [Levels of P27Kip1 expression and apoptosis in HL-60 cells after treatment with TGF-ß1 and/or arsenic trioxide]. 2010 Aug 1
52 21061466 Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway. 2010 1
53 19489279 [Effects of arsenic trioxide on human coronary smooth muscle cells: experiment in vitro]. 2009 Jan 13 1
54 19664237 Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction. 2009 Aug 8 1
55 18357729 In vitro arsenic trioxide induces apoptosis in T cells of asthmatic patients by a Bcl-2 related mechanism. 2008 Jan 3
56 18412143 The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. 2008 Oct 6
57 18599993 [Arsenic trioxide induced apoptosis in retinoblastoma cells in vitro and its possible mechanism]. 2008 Jun 1
58 18695917 Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. 2008 Sep 1
59 17203211 Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. 2007 Feb 1
60 17390014 Comparison of diarsenic oxide and tetraarsenic oxide on anticancer effects: relation to the apoptosis molecular pathway. 2007 May 1
61 17956674 [Mechanisms underlying the effect of arsenic trioxide on proliferation inhibition and apoptosis induction in myeloma cell line u266]. 2007 Oct 1
62 16904648 Arsenic trioxide induces gallbladder carcinoma cell apoptosis via downregulation of Bcl-2. 2006 Sep 29 7
63 17168655 Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug. 2006 Dec 1
64 15665116 Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells. 2005 May 15 1
65 15735709 Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells. 2005 May 5 1
66 16007134 Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway. 2005 Oct 27 2
67 16010437 Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia. 2005 Aug 1
68 14647451 Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. 2004 Feb 12 1
69 14726646 Arsenic trioxide and paclitaxel induce apoptosis by different mechanisms. 2004 Mar 1
70 15178684 Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis. 2004 Aug 6 1
71 15291359 Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway. 2004 May 1
72 15844663 Effect of arsenic trioxide (ATO) on human lung carcinoma PG cell line: ATO induced apoptosis of PG cells and decreased expression of Bcl-2, Pgp. 2004 Dec 4
73 12939460 Arsenic trioxide induces apoptosis in peripheral blood T lymphocyte subsets by inducing oxidative stress: a role of Bcl-2. 2003 Aug 1
74 14642526 Bcl-2 antisense oligodeoxynucleotide increases the sensitivity of leukemic cells to arsenic trioxide. 2003 5
75 12063550 Arsenic trioxide induces apoptosis through a reactive oxygen species-dependent pathway and loss of mitochondrial membrane potential in HeLa cells. 2002 Jul 1
76 12168106 Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt. 2002 Sep 1
77 12490120 [Arsenic trioxide induced apoptosis and expression of p53 and bcl-2 genes in human small cell lung cancer cells]. 2002 Nov 1
78 11468182 Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. 2001 Aug 1 2
79 11520058 Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells. 2001 Aug 31 1
80 11739184 Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage. 2001 Dec 15 1
81 11780464 Apoptosis inducing effects of arsenic trioxide on human bladder cancer cell line BIU-87. 2001 Apr 1
82 21106154 [A study on apoptosis induced by As₂O₃ for small cell lung cancer]. 2001 Dec 20 1
83 10811458 The effects of arsenic trioxide (As2O3) on human megakaryocytic leukemia cell lines. With a comparison of its effects on other cell lineages. 2000 Jun 2
84 11135700 [An experimental study on arsenic trioxide-selectively induced human hepatocarcinoma cell lines apoptosis and its related genes]. 2000 Dec 1
85 11775218 Overexpression of Bcl-2 partly inhibits apoptosis of human cervical cancer SiHa cells induced by arsenic trioxide. 2000 Jan 4
86 11819674 Effect of arsenic trioxide on human hepatoma cell line BEL-7402 cultured in vitro. 2000 Oct 4
87 11877007 [Regulation of telomerase activity in HL-60 and NB4 cells by arsenic trioxide]. 2000 Jul 1
88 12578669 [Effect of Arsenic Trioxide on Myelomonocytic Progenitor Cells in Patients with Myelodysplastic Syndrome in Vitro] 2000 Dec 2
89 18726487 Mechanisms of arsenic trioxide induced apoptosis of human cervical cancer HeLa cells and protection by Bcl-2. 1999 Dec 1
90 9737686 The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms. 1998 Sep 1
91 9129041 Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. 1997 May 1 1
92 15622746 [Preliminary study on the arsenic trioxide-induced NB4 cell apoptosis and its molecular mechanisms]. 1997 Jan 1
93 8704214 In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. 1996 Aug 1 4