| 1 |
34321365 | Natural Compound Shikonin Induces Apoptosis and Attenuates Epithelial to Mesenchymal Transition in Radiation-Resistant Human Colon Cancer Cells. | 2022 Mar 1 |
1 |
| 2 |
34504572 | Shikonin attenuates H2O2-induced oxidative injury in HT29 cells via antioxidant activities and the inhibition of mitochondrial pathway-mediated apoptosis. | 2021 Oct |
1 |
| 3 |
34646528 | Shikonin protects against lipopolysaccharide-induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor-kappa B pathway. | 2021 Oct |
1 |
| 4 |
32536866 | Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin. | 2020 |
1 |
| 5 |
29925224 | Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways. | 2019 Jan 1 |
2 |
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31452796 | Shikonin potentiates paclitaxel antitumor efficacy in esophageal cancer cells via the apoptotic pathway. | 2019 Sep |
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| 7 |
29449346 | Shikonin suppresses proliferation and induces apoptosis in endometrioid endometrial cancer cells via modulating miR-106b/PTEN/AKT/mTOR signaling pathway. | 2018 Apr 27 |
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| 8 |
30594131 | Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways. | 2018 Dec 29 |
1 |
| 9 |
25591861 | Functional and mechanistic investigation of Shikonin in scarring. | 2015 Feb 25 |
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| 10 |
25669168 | Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells. | 2015 Jul |
2 |
| 11 |
25720435 | Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-κB signalling pathway in human epidermoid carcinoma A431 cells. | 2015 Apr 28 |
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| 12 |
25879420 | Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway. | 2015 Apr 1 |
1 |
| 13 |
26235879 | Shikonin causes apoptosis by up-regulating p73 and down-regulating ICBP90 in human cancer cells. | 2015 Sep 11 |
1 |
| 14 |
24962386 | Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway. | 2014 Jun 11 |
1 |
| 15 |
22446899 | Novel multiple apoptotic mechanism of shikonin in human glioma cells. | 2012 Sep |
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| 16 |
20460760 | Shikonin induces apoptosis through reactive oxygen species/extracellular signal-regulated kinase pathway in osteosarcoma cells. | 2010 |
2 |
| 17 |
19027226 | Naturally-occurring shikonin analogues--a class of necroptotic inducers that circumvent cancer drug resistance. | 2009 Feb 18 |
1 |
| 18 |
15453709 | Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. | 2004 Oct 6 |
2 |