Celecoxib

BCL2 apoptosis regulator ; Homo sapiens







49 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35176901 Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma. 2022 Jan-Dec 1
2 32792943 Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells. 2020 1
3 31141661 Core-Shell Distinct Nanodrug Showing On-Demand Sequential Drug Release To Act on Multiple Cell Types for Synergistic Anticancer Therapy. 2019 Jun 25 2
4 31518663 Cisplatin induces chemoresistance through the PTGS2-mediated anti-apoptosis in gastric cancer. 2019 Nov 1
5 29541237 Celecoxib enhances sensitivity to chemotherapy drugs of T-cell lymphoma. 2018 Apr 1
6 28386348 Inhibition of COX-2/PGE2 cascade ameliorates cisplatin-induced mesangial cell apoptosis. 2017 1
7 28804691 Combination of celecoxib (Celebrex®) and CD19 CAR-redirected CTL immunotherapy for the treatment of B-cell non-Hodgkin's lymphomas. 2017 2
8 28962106 Effects of celecoxib on cell apoptosis and Fas, FasL and Bcl-2 expression in a BGC-823 human gastric cancer cell line. 2017 Sep 3
9 27894402 HSP90 inhibitor enhances anti-proliferative and apoptotic effects of celecoxib on HT-29 colorectal cancer cells via increasing BAX/BCL-2 ratio. 2016 Oct 31 3
10 25964548 Combining CAL-101 with Celecoxib Enhances Apoptosis of EBV-transformed B-Cells Through MAPK-induced ER Stress. 2015 May 1
11 26407653 Celecoxib enhanced the cytotoxic effect of cisplatin in drug-resistant human gastric cancer cells by inhibition of cyclooxygenase-2. 2015 Dec 15 1
12 26586936 Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth. 2015 1
13 24855827 Anticancer effects of celecoxib through inhibiton of STAT3 phosphorylation and AKT phosphorylation in nasopharyngeal carcinoma cell lines. 2014 May 1
14 24998564 Antiproliferative effects of celecoxib in Hep-2 cells through telomerase inhibition and induction of apoptosis. 2014 1
15 25050836 Synergistic effect of celecoxib in tumor necrosis factor‑related apoptosis‑inducing ligand treatment in osteosarcoma cells. 2014 Oct 3
16 21345578 Targeting apoptosis pathways by Celecoxib in cancer. 2013 May 28 2
17 23991582 [Celecoxib enhances the chemotherapy sensitivity of KB/VCR cell lines to vincristine]. 2013 Aug 1
18 22225575 Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. 2012 Apr 1
19 22393942 Celecoxib and Bcl-2: emerging possibilities for anticancer drug design. 2012 Mar 3
20 22415852 Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway. 2012 Jul 1
21 22504904 Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. 2012 May 1
22 20836993 Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis. 2011 Jan 1 3
23 21397587 Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells. 2011 Apr 15 1
24 22088287 [Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines]. 2011 Jul 1
25 19665451 Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on celecoxib-induced apoptosis. 2010 Jan 1 4
26 19967402 Suppression of human lung cancer cell growth and migration by berbamine. 2010 Aug 1
27 20104024 Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells. 2010 Feb 1
28 20305374 Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells. 2010 Apr 1 1
29 18923901 Anticancer effect of celecoxib via COX-2 dependent and independent mechanisms in human gastric cancers cells. 2009 Jul 2
30 19447220 Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line. 2009 Jul 1 1
31 19673886 Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenografts. 2009 Nov 1
32 19796390 Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. 2009 Oct 1 2
33 18078766 Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt. 2008 May 4
34 18083230 Imatinib-resistant K562 cells are more sensitive to celecoxib, a selective COX-2 inhibitor: role of COX-2 and MDR-1. 2008 Jun 1
35 18084318 Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29). 2008 Mar 1
36 18778687 Importance of Bak for celecoxib-induced apoptosis. 2008 Oct 30 5
37 17342322 Failure of apoptosis and activation on NFkappaB by celecoxib and aspirin in lung cancer cell lines. 2007 Apr 1
38 17510421 P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines. 2007 May 15 1
39 17695552 Celecoxib increased expression of 14-3-3sigma and induced apoptosis of glioma cells. 2007 Jul-Aug 4
40 16391871 Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer. 2006 Feb 2
41 16458114 Bcl-2 switches the type of demise from apoptosis to necrosis via cyclooxygenase-2 upregulation in HeLa cell induced by hydrogen peroxide. 2006 Feb 8 1
42 16615003 Effects of cyclooxygenase-2 inhibition on serum and tumor gastrins and expression of apoptosis-related proteins in colorectal cancer. 2006 Apr 1
43 17121918 Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells. 2006 Nov 1
44 15454489 A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism. 2005 Mar 15 1
45 15911099 Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro. 2005 Jun 16 1
46 14961568 Preclinical evaluation of the nonsteroidal anti-inflammatory agent celecoxib on malignant mesothelioma chemoprevention. 2004 Apr 10 1
47 12824303 Celecoxib activates a novel mitochondrial apoptosis signaling pathway. 2003 Aug 1
48 12297835 Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. 2002 Oct 1
49 10753955 The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. 2000 Apr 14 2