rasagiline

BCL2 apoptosis regulator ; Homo sapiens







16 Article(s)
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1 31993732 Rasagiline and selegiline modulate mitochondrial homeostasis, intervene apoptosis system and mitigate α-synuclein cytotoxicity in disease-modifying therapy for Parkinson's disease. 2020 Feb 1
2 29279995 Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons. 2018 Nov 1
3 28577058 Type B and A monoamine oxidase and their inhibitors regulate the gene expression of Bcl-2 and neurotrophic factors in human glioblastoma U118MG cells: different signal pathways for neuroprotection by selegiline and rasagiline. 2017 Sep 2
4 25832828 A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement. 2015 1
5 22892822 ''70th Birthday Professor Riederer'' induction of glial cell line-derived and brain-derived neurotrophic factors by rasagiline and (-)deprenyl: a way to a disease-modifying therapy? 2013 Jan 1
6 22968599 Rasagiline and selegiline, inhibitors of type B monoamine oxidase, induce type A monoamine oxidase in human SH-SY5Y cells. 2013 Mar 2
7 23739004 Revelation in the neuroprotective functions of rasagiline and selegiline: the induction of distinct genes by different mechanisms. 2013 Jun 1
8 22065207 Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase. 2012 Apr 6
9 19763773 Mitochondria in neurodegenerative disorders: regulation of the redox state and death signaling leading to neuronal death and survival. 2009 Nov 1
10 17982885 Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers. 2007 1
11 17447417 Involvement of type A monoamine oxidase in neurodegeneration: regulation of mitochondrial signaling leading to cell death or neuroprotection. 2006 1
12 15850677 Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. 2005 Apr 1
13 16148027 Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine. 2005 Nov 1
14 14555244 The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline. 2003 Oct 15 3
15 12057839 An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells. 2002 Jun 28 4
16 12200198 Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes. 2002 Sep-Oct 1