Tretinoin

BCL2 apoptosis regulator ; Homo sapiens







98 Article(s)
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51 12186376 Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells. 2002 Jul 2
52 12431242 Retinoid-induced apoptosis in B-cell chronic lymphocytic leukaemia cells is mediated through caspase-3 activation and is independent of p53, the retinoic acid receptor, and differentiation. 2002 Oct 1
53 12513735 [Study on telomerase activity and expression of hTERT, c-myc and bcl-2 during terminal differentiation of HL-60 cells induced by retinoic acid]. 2002 Oct 2
54 11181829 Antisense inhibition of BCL-2 expression induces retinoic acid-mediated cell death during differentiation of human NT2N neurons. 2001 Feb 8
55 11384110 Modulation of docetaxel-induced apoptosis and cell cycle arrest by all- trans retinoic acid in prostate cancer cells. 2001 Jun 1 2
56 11429697 Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathway in breast cancer cells. 2001 Jun 14 2
57 11561905 Differentiation-associated apoptosis of neural stem cells is effected by Bcl-2 overexpression: impact on cell lineage determination. 2001 Aug 1
58 11683923 Caspase-3 activity and expression of Bcl-2 family in human neutrophils by Helicobacter pylori water-soluble proteins. 2001 Sep 1
59 10623473 Retinoic acid differentiation of HL-60 cells promotes cytoskeletal polarization. 2000 Jan 10 1
60 10648421 Regulation of drug sensitivity by ribosomal protein S3a. 2000 Feb 1 2
61 10713328 All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor. 2000 Apr 4
62 10766196 1,25-Dihydroxyvitamin D3 and all-trans-retinoic acid sensitize breast cancer cells to chemotherapy-induced cell death. 2000 Apr 1 1
63 10816444 Bcl-2 accelerates retinoic acid-induced growth arrest and recovery in human gastric cancer cells. 2000 Jun 1 7
64 10940651 p53 pathway in apoptosis induced by all-trans-retinoic acid in acute myeloblastic leukaemia cells. 2000 1
65 11059564 Inhibition of the cytochrome P-450 modulates all-trans-retinoic acid-induced differentiation and apoptosis of HL-60 cells. 2000 1
66 11426618 Lovastatin induces a pronounced differentiation response in acute myeloid leukemias. 2000 Dec 1
67 10194425 Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome. 1999 Apr 15 2
68 10233386 An association between mitochondrial function and all-trans retinoic acid-induced apoptosis in acute myeloblastic leukaemia cells. 1999 Apr 2
69 10428509 Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39. 1999 Aug 1
70 10456672 Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bcl-2 in human myeloid leukaemia CD34 positive cells. 1999 Aug 5
71 10518116 Differential effects of staurosporine and retinoic acid on the vulnerability of the SH-SY5Y neuroblastoma cells: involvement of bcl-2 and p53 proteins. 1999 Nov 1 3
72 10557066 Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid. 1999 Nov 3
73 9558392 Constitutive expression of the promyelocytic leukemia-associated oncogene PML-RARalpha in TF1 cells: isoform-specific and retinoic acid-dependent effects on growth, bcl-2 expression, and apoptosis. 1998 May 1 2
74 9620283 All-trans retinoic acid modulates Fas antigen expression and affects cell proliferation and apoptosis in combination with anti-Fas monoclonal antibody in the human myeloma cell line, U266B1. 1998 Jun 2
75 9642262 Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells. 1998 Jul 3 1
76 9649124 A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells. 1998 Jun 1
77 9671760 Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. 1998 Jul 21 4
78 9716607 Phosphorylation of BCL-2 after exposure of human leukemic cells to retinoic acid. 1998 Sep 1 13
79 9779827 Evidence of a direct role for Bcl-2 in the regulation of articular chondrocyte apoptosis under the conditions of serum withdrawal and retinoic acid treatment. 1998 Nov 1 3
80 9225073 Modulation of p53, WAF1/p21 and BCL-2 expression during retinoic acid-induced differentiation of NB4 promyelocytic cells. 1997 May 1
81 9402847 In vitro down-regulation of bcl-2 expression by all-trans retinoic acid in AML blasts. 1997 Oct 6
82 9815594 all-trans retinoic acid enhances cisplatin-induced apoptosis in human ovarian adenocarcinoma and in squamous head and neck cancer cells. 1997 Nov 1
83 10743138 [Differentiation-inducing effect of stepholidine and retinoic acid on human head and neck carcinoma]. 1997 Apr 1
84 15624332 [9-cis retinoic acid induces apoptosis in HL-60 cells]. 1997 Jul 2
85 8603522 Retinoic acid modulates the in vivo and in vitro growth of IL-6 autocrine human myeloma cell lines via induction of apoptosis. 1996 Apr 1
86 8642855 Post-transcriptional regulation of bcl-2 in acute myeloblastic leukemia: significance for response to chemotherapy. 1996 Mar 1
87 8666983 Regulation of Bcl-2 protein expression in human neuroblastoma SH-SY5Y cells: positive and negative effects of protein kinases C and A, respectively. 1996 Jul 1
88 8713132 Differential effects of retinoic acid (RA) and N-(4-hydroxyphenyl) retinamide (4-HPR) on cell growth, induction of differentiation, and changes in p34cdc2, Bcl-2, and actin expression in the human promyelocytic HL-60 leukemic cells. 1996 Jul 25 2
89 8790944 Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3. 1996 Apr 2
90 8826891 Down-regulation of bcl-2 in AML blasts by all-trans retinoic acid and its relationship to CD34 antigen expression. 1996 Sep 11
91 8830674 Co-ordinated downregulation of bcl-2 and bax expression during granulocytic and macrophage-like differentiation of the HL60 promyelocytic leukaemia cell line. 1996 Oct 7 2
92 7553653 Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance. 1995 Oct 15 1
93 7564507 Direct evidence for the participation of bcl-2 in the regulation by retinoic acid of the Ara-C sensitivity of leukemic stem cells. 1995 Oct 4
94 7630193 Distinct apoptotic responses in maturation sensitive and resistant t(15;17) acute promyelocytic leukemia NB4 cells. 9-cis retinoic acid induces apoptosis independent of maturation and Bcl-2 expression. 1995 Jul 1
95 7769841 Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals. 1995 May 7
96 8609716 In vitro treatment with retinoids or the topoisomerase inhibitor, VP-16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells. 1995 Dec 1
97 8161792 Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells. 1994 Apr 15 2
98 8402688 Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells. 1993 Oct 15 1