Bicarbonates

solute carrier family 4 member 4 ; Homo sapiens







49 Article(s)
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1 35305629 SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway. 2022 Mar 19 2
2 35635440 Inhibition of the sodium-dependent HCO3- transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype. 2022 May 30 4
3 32776463 Duodenal mucosal secretory disturbances in functional dyspepsia. 2021 Jan 1
4 34584093 Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. 2021 Sep 28 1
5 32969493 Carbonic anhydrases enhance activity of endogenous Na-H exchangers and not the electrogenic Na/HCO3 cotransporter NBCe1-A, expressed in Xenopus oocytes. 2020 Dec 7
6 33033238 Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle. 2020 Oct 8 1
7 27338124 A novel mutant Na+ /HCO3- cotransporter NBCe1 in a case of compound-heterozygous inheritance of proximal renal tubular acidosis. 2016 Nov 1 1
8 25612232 The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells. 2015 Aug 2
9 24982885 Roles of renal proximal tubule transport in acid/base balance and blood pressure regulation. 2014 1
10 23324180 Substrate specificity of the electrogenic sodium/bicarbonate cotransporter NBCe1-A (SLC4A4, variant A) from humans and rabbits. 2013 Apr 1 3
11 23362273 Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation. 2013 Mar 15 1
12 23636456 Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. 2013 Aug 15 1
13 23832211 X-ray diffraction studies on merohedrally twinned Δ1-62NtNBCe1-A crystals of the sodium/bicarbonate cotransporter. 2013 Jul 1
14 24101904 Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO3 (-) cotransporter NBCe1. 2013 Oct 1 2
15 24391589 Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties. 2013 Dec 19 1
16 22316307 pH-sensitive self-associations of the N-terminal domain of NBCe1-A suggest a compact conformation under acidic intracellular conditions. 2012 Oct 2
17 21224233 Role of an extracellular loop in determining the stoichiometry of Na+-HCO₃⁻ cotransporters. 2011 Feb 15 1
18 20197274 Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. 2010 Apr 30 1
19 21242704 Primers on molecular pathways: bicarbonate transport by the pancreas. 2010 2
20 18614622 G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. 2008 Sep 1
21 17192275 Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. 2007 Mar 23 1
22 17652713 Identification and characterization of a novel mutation in the carbonic anhydrase IV gene that causes retinitis pigmentosa. 2007 Aug 2
23 16622177 Role of NH(2) and COOH termini in targeting, stability, and activity of sodium bicarbonate cotransporter 1. 2006 Sep 1
24 16785749 Localization of NBC1 variants in rat kidney. 2006 1
25 17071329 The sodium bicarbonate cotransporter: structure, function, and regulation. 2006 Sep 1
26 15563508 Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration. 2005 Jan 15 2
27 15218065 Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. 2004 Aug 15 1
28 15273250 Identification of a carboxyl-terminal motif essential for the targeting of Na+-HCO-3 cotransporter NBC1 to the basolateral membrane. 2004 Oct 8 1
29 15283764 Sodium coupled bicarbonate transporters in the kidney, an update. 2004 Aug 2
30 15366422 Regulation of renal Na+/HCO3- cotransporter stimulation by CO2: role of phosphorylation, exocytosis and protein synthesis. 2004 May 1 1
31 15471865 A novel missense mutation in the sodium bicarbonate cotransporter (NBCe1/SLC4A4) causes proximal tubular acidosis and glaucoma through ion transport defects. 2004 Dec 10 1
32 15499994 The bicarbonate transport metabolon. 2004 Jun 1
33 12847417 Functional and molecular properties of Na+:HCO-3 cotransporters (NBC). 2003 Jun 2
34 14559244 Localization of NBC-1 variants in human kidney and renal cell carcinoma. 2003 Oct 31 4
35 14729154 Integrated responses of Na+/HCO3- cotransporters and V-type H+-ATPases in the fish gill and kidney during respiratory acidosis. 2003 Dec 30 5
36 12027220 Na+:HCO3- cotransporters (NBC): expression and regulation in the kidney. 2002 Mar-Apr 2
37 12372762 Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry. 2002 Nov 2
38 12411514 Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding. 2002 Nov 1 4
39 11435462 Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. 2001 Jul 4
40 11562789 Na+:HCO(3-) cotransporters (NBC): cloning and characterization. 2001 Sep 15 3
41 11592950 Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye. 2001 Nov 2
42 11875265 Impaired pancreatic ductal bicarbonate secretion in cystic fibrosis. 2001 Jul 1
43 10652014 Physiologic and molecular aspects of the Na+:HCO3- cotransporter in health and disease processes. 2000 Feb 1
44 11087115 Two C-terminal variants of NBC4, a new member of the sodium bicarbonate cotransporter family: cloning, characterization, and localization. 2000 Jul 1
45 11131345 Genetic and long-term data on a patient with permanent isolated proximal renal tubular acidosis. 2000 Dec 1
46 11193561 Expression and function of Na+HCO3- cotransporters in the gastrointestinal tract. 2000 1
47 10519138 Functional and molecular evidence for Na(+)-HCO3- cotransporter in human corneal endothelial cells. 1999 Sep 1
48 8599028 The renal cortical Na-HCO3 cotransporter: V. expression in Xenopus oocytes. 1996 Feb 1
49 1314505 Regulation of the renal Na-HCO3 cotransporter by cAMP and Ca-dependent protein kinases. 1992 Apr 1