| 1 |
33749884 | Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models. | 2021 Apr |
1 |
| 2 |
34818331 | Antinociceptive and anti-inflammatory effects of hydrazone derivatives and their possible mechanism of action in mice. | 2021 |
1 |
| 3 |
32595743 | Guizhi Fuling Capsule Exhibits Antidysmenorrhea Activity by Inhibition of Cyclooxygenase Activity. | 2020 |
1 |
| 4 |
31469551 | Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex. | 2019 Sep 24 |
1 |
| 5 |
28819782 | The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line. | 2018 Apr |
1 |
| 6 |
29326169 | Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. | 2018 Mar 2 |
1 |
| 7 |
30059558 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. | 2018 |
1 |
| 8 |
27012456 | Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1. | 2016 Apr |
1 |
| 9 |
27875294 | Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 (STIMULATORY PROTEIN-1). | 2016 Dec 30 |
1 |
| 10 |
25825493 | Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2. | 2015 May 15 |
1 |
| 11 |
26305786 | Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection. | 2015 |
1 |
| 12 |
26406890 | Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. | 2015 |
1 |
| 13 |
24480038 | PGE2 production is suppressed by chemically-synthesized Δ7-eicosatrienoic acid in macrophages through the competitive inhibition of COX-2. | 2014 Apr |
1 |
| 14 |
22225576 | Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide. | 2013 Feb |
1 |
| 15 |
24015204 | 2-hydroxy arachidonic acid: a new non-steroidal anti-inflammatory drug. | 2013 |
2 |
| 16 |
21856425 | Neuromodulatory role of endogenous interleukin-1β in acute seizures: possible contribution of cyclooxygenase-2. | 2012 Jan |
1 |
| 17 |
22227329 | In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation. | 2012 Mar 5 |
1 |
| 18 |
22412193 | Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation. | 2012 Apr 15 |
1 |
| 19 |
22551156 | Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase. | 2012 Oct |
3 |
| 20 |
22637474 | Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove. | 2012 Jul 13 |
1 |
| 21 |
23008450 | COX-2 expression is upregulated by DNA hypomethylation after hematopoietic stem cell transplantation. | 2012 Nov 1 |
1 |
| 22 |
21489986 | The structural basis of endocannabinoid oxygenation by cyclooxygenase-2. | 2011 Jun 10 |
1 |
| 23 |
21843643 | The structure of NS-398 bound to cyclooxygenase-2. | 2011 Nov |
1 |
| 24 |
19710084 | Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors. | 2010 Feb 1 |
1 |
| 25 |
19752399 | Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2. | 2010 Mar |
1 |
| 26 |
19996299 | Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung. | 2010 Mar |
1 |
| 27 |
20463020 | Structural basis of fatty acid substrate binding to cyclooxygenase-2. | 2010 Jul 16 |
1 |
| 28 |
21030497 | Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice. | 2010 Dec 1 |
1 |
| 29 |
19114118 | Up-regulation of microsomal prostaglandin E synthase-1 in COX-1 and COX-2 knock-out mouse fibroblast cell lines. | 2009 Apr |
1 |
| 30 |
18597804 | UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes. | 2008 Oct 1 |
1 |
| 31 |
17199550 | Cyclooxygenase-2-dependent prostaglandin E(2) upregulates interleukin (IL)-1alpha-induced IL-6 generation in mouse cementoblasts. | 2007 Jan |
1 |
| 32 |
17202128 | Altered brain lipid composition in cyclooxygenase-2 knockout mouse. | 2007 Apr |
1 |
| 33 |
17204299 | Role of cyclooxygenases in oedema-forming activity of bothropic venoms. | 2007 Apr |
1 |
| 34 |
17241427 | Arachidonic acid inhibits osteoblast differentiation through cytosolic phospholipase A2-dependent pathway. | 2007 Jan |
3 |
| 35 |
17266762 | Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain. | 2007 |
1 |
| 36 |
17303115 | Effect of NC-1900, an active fragment analog of arginine vasopressin, and inhibitors of arachidonic acid metabolism on performance of a passive avoidance task in mice. | 2007 Mar 29 |
1 |
| 37 |
16405503 | Resting and arecoline-stimulated brain metabolism and signaling involving arachidonic acid are altered in the cyclooxygenase-2 knockout mouse. | 2006 Feb |
1 |
| 38 |
16510568 | Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer. | 2006 Mar 1 |
1 |
| 39 |
16762422 | Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. | 2006 Jul 15 |
1 |
| 40 |
15637091 | Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke. | 2005 Apr |
2 |
| 41 |
15863457 | Vasoactive prostanoids are generated from arachidonic acid by COX-1 and COX-2 in the mouse. | 2005 Oct |
1 |
| 42 |
16128405 | Cyclooxygenases and prostaglandin E synthases in preimplantation mouse embryos. | 2005 May |
1 |
| 43 |
16198098 | Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells. | 2005 Dec |
1 |
| 44 |
16254252 | Cardiovascular complications of non-steroidal anti-inflammatory drugs. | 2005 Autumn |
1 |
| 45 |
14769824 | Cyclooxygenase 2 is a key enzyme for inflammatory cytokine-induced angiogenesis. | 2004 Feb |
1 |
| 46 |
15223810 | Endotoxin-induced uveitis in cyclooxygenase-2-deficient mice. | 2004 Jul |
1 |
| 47 |
15584915 | Prostaglandin E2 and microsomal prostaglandin E synthase-2 expression are decreased in the cyclooxygenase-2-deficient mouse brain despite compensatory induction of cyclooxygenase-1 and Ca2+-dependent phospholipase A2. | 2004 Dec |
1 |
| 48 |
12709576 | Regulation of heme oxygenase expression by cyclopentenone prostaglandins. | 2003 May |
1 |
| 49 |
12902868 | Celecoxib reduces skin damage after radiation: selective reduction of chemokine and receptor mRNA expression in irradiated skin but not in irradiated mammary tumor. | 2003 Aug |
1 |
| 50 |
12126310 | Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches. | 2002 Jul |
1 |