| 1 |
35165396 | Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit. | 2022 Mar |
2 |
| 2 |
32941796 | Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila. | 2021 Apr |
2 |
| 3 |
32242231 | Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease. | 2020 May 28 |
2 |
| 4 |
32978366 | pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model. | 2020 Sep 25 |
1 |
| 5 |
31088970 | IKKβ slows Huntington's disease progression in R6/1 mice. | 2019 May 28 |
2 |
| 6 |
27466181 | Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization. | 2016 Sep 15 |
1 |
| 7 |
27525439 | Serine 421 regulates mutant huntingtin toxicity and clearance in mice. | 2016 Sep 1 |
3 |
| 8 |
24301680 | FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease. | 2014 May 1 |
1 |
| 9 |
24951540 | Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α. | 2014 Nov 15 |
2 |
| 10 |
25038828 | Huntington's disease is a four-repeat tauopathy with tau nuclear rods. | 2014 Aug |
1 |
| 11 |
25057205 | Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex. | 2014 Jul 23 |
1 |
| 12 |
23409115 | Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease. | 2013 |
1 |
| 13 |
23678106 | Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. | 2013 May 15 |
1 |
| 14 |
22623107 | Mass spectrometric identification of novel posttranslational modification sites in Huntingtin. | 2012 Jun |
1 |
| 15 |
22999956 | Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties. | 2012 Nov 23 |
2 |
| 16 |
21245084 | Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation. | 2011 Apr 1 |
1 |
| 17 |
21623356 | Kinase inhibitors modulate huntingtin cell localization and toxicity. | 2011 May 29 |
2 |
| 18 |
20064390 | Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. | 2009 Dec 24 |
3 |
| 19 |
17352936 | Selective degeneration in YAC mouse models of Huntington disease. | 2007 Apr 30 |
2 |
| 20 |
15843398 | Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo. | 2005 Jun 1 |
3 |
| 21 |
14522959 | Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells. | 2003 Dec 12 |
1 |