| 1 |
35143966 | Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice. | 2022 May |
2 |
| 2 |
34918046 | Therapeutic reversal of Huntington's disease by in vivo self-assembled siRNAs. | 2021 Dec 16 |
4 |
| 3 |
31648394 | Mesenchymal stem cells alleviate AQP-4-dependent glymphatic dysfunction and improve brain distribution of antisense oligonucleotides in BACHD mice. | 2020 Feb |
1 |
| 4 |
30282695 | Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease. | 2018 Oct 3 |
1 |
| 5 |
28182673 | The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain. | 2017 |
2 |
| 6 |
28453524 | Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. | 2017 |
2 |
| 7 |
27033979 | Enhanced immune response to MMP3 stimulation in microglia expressing mutant huntingtin. | 2016 Jun 14 |
1 |
| 8 |
27721240 | Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels. | 2016 Nov 1 |
2 |
| 9 |
24347167 | Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin. | 2014 Feb 7 |
1 |
| 10 |
24380395 | Preventing formation of toxic N-terminal huntingtin fragments through antisense oligonucleotide-mediated protein modification. | 2014 Feb |
4 |
| 11 |
25035419 | Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity. | 2014 Dec 1 |
2 |
| 12 |
25101598 | In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides. | 2014 Dec |
1 |
| 13 |
25155142 | Targets for future clinical trials in Huntington's disease: what's in the pipeline? | 2014 Sep 15 |
1 |
| 14 |
25063516 | Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease. | 2013 |
1 |
| 15 |
22726826 | "Huntingtin holiday": progress toward an antisense therapy for Huntington's disease. | 2012 Jun 21 |
1 |
| 16 |
22726834 | Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. | 2012 Jun 21 |
2 |
| 17 |
12165556 | Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. | 2002 Aug 15 |
1 |