Oximes

peptidylglycine alpha-amidating monooxygenase ; Homo sapiens







18 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32175496 Molecular Modeling Study of Uncharged Oximes Compared to HI-6 and 2-PAM Inside Human AChE Sarin and VX Conjugates. 2020 Mar 10 3
2 32267631 A novel high-performance liquid chromatography with diode array detector method for the simultaneous quantification of the enzyme-reactivating oximes obidoxime, pralidoxime, and HI-6 in human plasma. 2020 Jul 1
3 31276662 Reactivation potency of two novel oximes (K456 and K733) against paraoxon-inhibited acetyl and butyrylcholinesterase: In silico and in vitro models. 2019 Sep 1 1
4 28446076 Behavior of uncharged oximes compared to HI6 and 2-PAM in the human AChE-tabun conjugate: a molecular modeling approach. 2018 May 1
5 29062551 In Vitro Cysteine Reactivates Organophosphate Insecticide Dichlorvos-Inhibited Human Cholinesterases. 2017 Aug 1
6 26368669 Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes. 2015 Dec 25 1
7 23314320 A physiologically based pharmacokinetic model for the oxime TMB-4: simulation of rodent and human data. 2013 Apr 1
8 22125290 Preparing for chemical terrorism: a study of the stability of expired pralidoxime (2-PAM). 2012 Mar 1
9 21524678 Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning. 2011 Jul 29 1
10 19465093 Effects of oximes on mitochondrial oxidase activity. 2009 Sep 10 1
11 19642642 Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime. 2009 Dec 10 1
12 17151865 Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro. 2007 Jun 2
13 17370870 Pralidoxime in carbaryl poisoning: an animal model. 2007 Feb 1
14 16266695 Estimation of oxime efficacy in nerve agent poisoning: a kinetic approach. 2005 Dec 15 1
15 14529460 Mechanism of organophosphates (nerve gases and pesticides) and antidotes: electron transfer and oxidative stress. 2003 Dec 1
16 2818204 Pharmacokinetics of pralidoxime chloride. A comparative study in healthy volunteers and in organophosphorus poisoning. 1989 1
17 2452874 Acetylcholinesterase reactivators modify the functional properties of the nicotinic acetylcholine receptor ion channel. 1988 May 2
18 14026286 Medical aspects of chemical warfare. 1962 Dec 1 1