Tolterodine Tartrate

histamine N-methyltransferase ; Homo sapiens







8 Article(s)
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Title
Pub. Year
#Total Relationships
1 30542809 Influence of CYP2D6 genetic polymorphism on pharmacokinetics of active moiety of tolterodine. 2019 Feb 1
2 29995258 Virtual Thorough QT (TQT) Trial-Extrapolation of In Vitro Cardiac Safety Data to In Vivo Situation Using Multi-Scale Physiologically Based Ventricular Cell-wall Model Exemplified with Tolterodine and Fesoterodine. 2018 Jul 11 1
3 29128914 Simultaneous determination of tolterodine and its two metabolites, 5-hydroxymethyltolterodine and N-dealkyltolterodine in human plasma using LC-MS/MS and its application to a pharmacokinetic study. 2017 Nov 1
4 23497983 Fesoterodine, its active metabolite, and tolterodine bind selectively to muscarinic receptors in human bladder mucosa and detrusor muscle. 2013 Apr 1
5 21352267 Comparison of pharmacokinetic variability of fesoterodine vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers. 2011 Aug 7
6 19145494 The pharmacokinetic profile of fesoterodine: similarities and differences to tolterodine. 2009 Mar 7 1
7 19835561 The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. 2009 2
8 19956551 Fesoterodine for the treatment of urinary incontinence and overactive bladder. 2009 2