Arsenic Trioxide

BCL2 associated X, apoptosis regulator ; Homo sapiens







52 Article(s)
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1 35487055 Human prostate cancer cell epithelial-to-mesenchymal transition as a novel target of arsenic trioxide and curcumin therapeutic approach. 2022 Jun 1
2 34659521 Metformin and arsenic trioxide synergize to trigger Parkin/pink1-dependent mitophagic cell death in human cervical cancer HeLa cells. 2021 1
3 32642412 Arsenic trioxide induces regulatory functions of plasmacytoid dendritic cells through interferon- α inhibition. 2020 Jun 1
4 30668372 Evaluation of phyto-medicinal efficacy of thymoquinone against Arsenic induced mitochondrial dysfunction and cytotoxicity in SH-SY5Y cells. 2019 Feb 15 1
5 31079498 Study of As2O3 regulating proliferation and apoptosis of Tca8113 cells by inhibiting the expression of Id-1. 2019 Dec 1
6 29959200 Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells. 2018 Sep 1
7 30600718 The effect of simultaneous administration of arsenic trioxide and microvesicles derived from human bone marrow mesenchymal stem cells on cell proliferation and apoptosis of acute myeloid leukemia cell line. 2018 1
8 28239804 Arsenic trioxide regulates gastric cancer cell apoptosis by mediating cAMP. 2017 Feb 1
9 28823259 [Synergistic Killing Effects of Arsenic Trioxide Combined with Itraconazole on KG1a Cells]. 2017 Aug 1
10 28966729 Arsenic Trioxide Induces Apoptosis via Specific Signaling Pathways in HT-29 Colon Cancer Cells. 2017 Jan 1
11 29164574 Mechanism of As2O3 induces apoptosis of glioma U87 cells. 2017 Nov 1
12 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 1
13 26883975 Biocompatible arsenic trioxide nanoparticles induce cell cycle arrest by p21(WAF1/CIP1) expression via epigenetic remodeling in LNCaP and PC3 cell lines. 2016 Mar 1 1
14 27039805 Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-κB-Mediated Mechanism. 2016 1
15 27812249 The Synergistic Effects of Decitabine Combined with Arsenic Trioxide (ATO) in the Human Myelodysplastic Syndrome Cell Line SKM-1. 2016 Dec 1
16 24993472 Arsenic trioxide inhibits DNA methyltransferase and restores TMS1 gene expression in K562 cells. 2015 1
17 25416439 Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activation. 2015 Apr 1
18 26117010 [Effects of As2O3 on the Proliferation, Differentiation and Apoptosis of HL-60 Cells and Its Related Mechanisms]. 2015 Jun 1
19 24466103 Arsenic trioxide induces apoptosis in human platelets via C-Jun NH2-terminal kinase activation. 2014 1
20 24666483 [Effects of arsenic trioxide on the methylation of TMS1 gene in K562 cells]. 2014 Mar 1
21 24738333 Antitumor efficacy of DMSA modified Fe3O4 magnetic nanoparticles combined with arsenic trioxide and adriamycin in Raji cells. 2014 Feb 1
22 24944602 Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1. 2014 Jul 2
23 25128771 Arsenic trioxide exerts a double effect on osteoblast growth in vitro. 2014 Sep 1
24 25130820 [Apoptosis-inducing effect of valproic acid combined with arsenic trioxide on RPMI 8226 cells and its mechanism]. 2014 Aug 1
25 25174355 E2F1 downregulation by arsenic trioxide in lung adenocarcinoma. 2014 Nov 1
26 25338570 [Synergistic killing effect of arsenic trioxide combined with curcumin on KG1a cells]. 2014 Oct 1
27 24356076 MicroRNAs contribute to promyelocyte apoptosis in As2O3-treated APL cells. 2013 1
28 22922982 Radiosensitizing effects of arsenic trioxide on MCF-7 human breast cancer cells exposed to 89 strontium chloride. 2012 Nov 2
29 23041229 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways. 2012 Dec 15 1
30 20164150 The expression of p38, ERK1 and Bax proteins has increased during the treatment of newly diagnosed acute promyelocytic leukemia with arsenic trioxide. 2010 Sep 1
31 20403207 The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. 2010 Apr 20 4
32 20605902 Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. 2010 Oct 1
33 21061466 Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway. 2010 1
34 19489279 [Effects of arsenic trioxide on human coronary smooth muscle cells: experiment in vitro]. 2009 Jan 13 1
35 19664237 Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction. 2009 Aug 8 1
36 18359480 Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines. 2008 May 15 1
37 18412143 The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. 2008 Oct 6
38 18599993 [Arsenic trioxide induced apoptosis in retinoblastoma cells in vitro and its possible mechanism]. 2008 Jun 1
39 18695917 Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. 2008 Sep 1
40 16882451 Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. 2007 Mar 3
41 17203211 Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. 2007 Feb 2
42 17237268 Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. 2007 Jan 2
43 17390014 Comparison of diarsenic oxide and tetraarsenic oxide on anticancer effects: relation to the apoptosis molecular pathway. 2007 May 1
44 17404572 Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax. 2007 Sep 13 3
45 17673311 Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. 2007 Nov 1
46 15665116 Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells. 2005 May 15 1
47 15735709 Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells. 2005 May 5 3
48 16010437 Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia. 2005 Aug 1
49 15131059 Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53. 2004 May 1 1
50 11135700 [An experimental study on arsenic trioxide-selectively induced human hepatocarcinoma cell lines apoptosis and its related genes]. 2000 Dec 1