tBID

BCL2 associated X, apoptosis regulator ; Homo sapiens







72 Article(s)
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Pub. Year
#Total Relationships
1 34931711 BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. 2022 Dec 17 4
2 33843148 Evaluating the inhibitory priority of Bcl-xL to Bad, tBid and Bax by using live-cell imaging assay. 2021 Nov 3
3 34263972 An Autophagy-Disrupting Small Molecule Promotes Cancer Cell Death via Caspase Activation. 2021 Dec 10 1
4 34361006 Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane. 2021 Jul 31 3
5 31492967 Stoichiometry and regulation network of Bcl-2 family complexes quantified by live-cell FRET assay. 2020 Jun 1
6 32126227 Lipid asymmetry of a model mitochondrial outer membrane affects Bax-dependent permeabilization. 2020 Aug 1 1
7 33614474 ClC-5 Downregulation Induces Osteosarcoma Cell Apoptosis by Promoting Bax and tBid Complex Formation. 2020 1
8 30536001 Liposomal Permeabilization Assay to Study the Functional Interactions of the BCL-2 Family. 2019 1
9 29022237 Dysfunction of Membrane Trafficking Leads to Ischemia-Reperfusion Injury After Transient Cerebral Ischemia. 2018 Jun 2
10 29265109 Humanin decreases mitochondrial membrane permeability by inhibiting the membrane association and oligomerization of Bax and Bid proteins. 2018 Jun 3
11 29567940 Bax retrotranslocation potentiates Bcl-xL's antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance. 2018 Apr 1 4
12 29706657 Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors. 2018 Jul 2
13 26794447 Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis. 2016 Jul 2
14 25633293 DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. 2015 Jan 29 1
15 25714678 Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax. 2015 May 1 1
16 26231047 Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim. 2015 Aug 1 2
17 24269536 Structural insights into proapoptotic signaling mediated by MTCH2, VDAC2, TOM40 and TOM22. 2014 Feb 6
18 24333953 Involvement of cardiolipin in tBID-induced activation of BAX during apoptosis. 2014 Apr 2
19 24464226 A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage. 2014 May 1
20 24901048 Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid. 2014 Jun 5 5
21 25077544 JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1. 2014 Jul 31 1
22 25288797 Integration and oligomerization of Bax protein in lipid bilayers characterized by single molecule fluorescence study. 2014 Nov 14 1
23 23744079 tBid undergoes multiple conformational changes at the membrane required for Bax activation. 2013 Jul 26 4
24 24158446 Structural insights of tBid, the caspase-8-activated Bid, and its BH3 domain. 2013 Dec 13 3
25 22513214 The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells. 2012 Aug 1 1
26 22761256 Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis. 2012 Oct 1
27 21130780 The Bcl-2-associated death promoter (BAD) lowers the threshold at which the Bcl-2-interacting domain death agonist (BID) triggers mitochondria disintegration. 2011 Feb 21 2
28 21525171 Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis. 2011 Jun 15 1
29 22036586 A unified model of mammalian BCL-2 protein family interactions at the mitochondria. 2011 Nov 18 1
30 19640637 Bid integrates intrinsic and extrinsic signaling in apoptosis induced by alpha-tocopheryl succinate in human gastric carcinoma cells. 2010 Feb 1 1
31 20083086 MAC and Bcl-2 family proteins conspire in a deadly plot. 2010 Jun-Jul 2
32 20404718 HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. 2010 May 15 1
33 20655869 BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation. 2010 Nov 5
34 20850011 Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization. 2010 Sep 17 1
35 19228717 Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. 2009 Feb 15 1
36 19450542 Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis. 2009 Oct 1
37 19466402 Activation of Bax by joint action of tBid and mitochondrial outer membrane: Monte Carlo simulations. 2009 Sep 11
38 19557009 Bax activation by Bim? 2009 Sep 1
39 19670908 Mapping the interaction of pro-apoptotic tBID with pro-survival BCL-XL. 2009 Sep 15 1
40 17724464 Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. 2008 Feb 28 1
41 18084240 Bax activation and stress-induced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes. 2008 Mar 2
42 18191430 Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A. 2008 Mar 15 1
43 18195012 BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes. 2008 Mar 21 4
44 18252800 Evaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c release. 2008 Mar 1 1
45 18547146 Bcl-XL inhibits membrane permeabilization by competing with Bax. 2008 Jun 10 6
46 19062087 Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. 2008 Dec 12 6
47 19070569 Bcl-2 proteins and apoptosis: choose your partner. 2008 Dec 12 1
48 17440103 Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells. 2007 Apr 15 1
49 17520191 Real-time monitoring full length bid interacting with Bax during TNF-alpha-induced apoptosis. 2007 Sep 2
50 17825286 In vitro analysis of Bcl-2 proteins in mitochondria and endoplasmic reticulum: similarities in anti-apoptotic functions and differences in regulation. 2007 Oct 15 2