Urea

argininosuccinate lyase ; Homo sapiens







39 Article(s)
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1 32949613 Multi-omics analysis reveals that co-exposure to phthalates and metals disturbs urea cycle and choline metabolism. 2021 Jan 1
2 34861885 ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism. 2021 Dec 3 3
3 32410394 Clinical and genetic analysis of five Chinese patients with urea cycle disorders. 2020 Jul 2
4 30613774 Improving the metabolic fidelity of cancer models with a physiological cell culture medium. 2019 Jan 1
5 30901224 Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. 2019 May 3 1
6 32042869 Down-regulation of argininosuccinate lyase induces hepatoma cell apoptosis through activating Bax signaling pathway. 2019 Sep 2
7 30158522 Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer. 2018 Aug 29 2
8 30176945 Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours. 2018 Sep 3 1
9 31037164 [Vomiting associated with weight stagnation and convulsions: urea cycle disorder should be suspected]. 2018 1
10 26731266 Lys-315 at the Interfaces of Diagonal Subunits of δ-Crystallin Plays a Critical Role in the Reversibility of Folding and Subunit Assembly. 2016 1
11 26745957 Effect of Cysteamine on Mutant ASL Proteins with Cysteine for Arginine Substitutions. 2016 Apr 2
12 25634685 Effect of high-fat diet on hepatic proteomics of hamsters. 2015 Feb 18 2
13 25778938 Unstable argininosuccinate lyase in variant forms of the urea cycle disorder argininosuccinic aciduria. 2015 Sep 3
14 24166829 Mutations and polymorphisms in the human argininosuccinate lyase (ASL) gene. 2014 Jan 3
15 21963434 α-Crystallin protects human arginosuccinate lyase activity under freeze-thaw conditions. 2012 Feb 1
16 22531684 Reduced expression of argininosuccinate lyase is closely associated with postresectional survival in hepatocellular carcinoma: an immunohistochemistry study of 61 cases. 2012 Dec 2
17 20167786 Regulation of cellular metabolism by protein lysine acetylation. 2010 Feb 19 1
18 18666241 Genetic variation in the urea cycle: a model resource for investigating key candidate genes for common diseases. 2009 Jan 2
19 19217439 Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects. 2009 Mar 2
20 19703900 Functional complementation in yeast allows molecular characterization of missense argininosuccinate lyase mutations. 2009 Oct 16 1
21 16808909 Argininosuccinate lyase deficiency (ASL) and carbohydrate-deficient transferrin (CDT): experience with four independent CDT analysis methods--misleading results given by the %CDT TIA assay. 2006 Nov 1
22 15320872 Structural studies of duck delta2 crystallin mutants provide insight into the role of Thr161 and the 280s loop in catalysis. 2004 Dec 1 2
23 11698398 Mutational analysis of duck delta 2 crystallin and the structure of an inactive mutant with bound substrate provide insight into the enzymatic mechanism of argininosuccinate lyase. 2002 Feb 8 1
24 11747432 Three-dimensional structure of the argininosuccinate lyase frequently complementing allele Q286R. 2001 Dec 25 2
25 10709858 The preferred source of arginine for high-output nitric oxide synthesis in blood vessels. 2000 Feb 2
26 11092456 Intragenic complementation and the structure and function of argininosuccinate lyase. 2000 Oct 1
27 10091655 Domain exchange experiments in duck delta-crystallins: functional and evolutionary implications. 1999 Mar 2
28 8867809 Argininosuccinate synthetase and argininosuccinate lyase are localized around mitochondria: an immunocytochemical study. 1996 Mar 1 1
29 7511585 Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis. 1994 Apr 1 1
30 20301396 Urea Cycle Disorders Overview 1993 1
31 21290785 Argininosuccinate Lyase Deficiency 1993 1
32 2235124 Development of ornithine metabolism in the mouse intestine. 1990 Sep 1
33 2259230 Elevated argininosuccinate synthetase activity in adult T leukemia cell lines. 1990 1
34 2834354 Amino acid sequence of rat argininosuccinate lyase deduced from cDNA. 1988 Jan 2
35 7329991 Urea cycle and protein content in leucocytes from normal persons and uraemics. 1981 1
36 282632 Argininosuccinic aciduria: assignment of the argininosuccinate lyase gene to the pter to q22 region of human chromosome 7 by bioautography. 1978 Dec 1
37 337792 Urea biosynthesis I. The urea cycle and relationships to the citric acid cycle. 1977 Dec 1
38 885138 Urea as a selective inhibitor of argininosuccinate lyase. 1977 May 16 2
39 893492 Immobilization of urea cycle enzymes. II. Characterization of immobilized argininosuccinate synthetase. 1977 Sep 1