Citric Acid

solute carrier family 13 member 5 ; Homo sapiens







36 Article(s)
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1 35448460 L-Arginine and Cardioactive Arginine Derivatives as Substrates and Inhibitors of Human and Mouse NaCT/Nact. 2022 Mar 22 2
2 35448538 Untargeted Metabolomics of Slc13a5 Deficiency Reveal Critical Liver-Brain Axis for Lipid Homeostasis. 2022 Apr 14 1
3 33544126 Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood-brain barrier. 2021 Feb 12 4
4 33597751 Structure and inhibition mechanism of the human citrate transporter NaCT. 2021 Mar 4
5 34101804 A home run for human NaCT/SLC13A5/INDY: cryo-EM structure and homology model to predict transport mechanisms, inhibitor interactions and mutational defects. 2021 Jun 11 2
6 34323067 Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD. 2021 Aug 11 3
7 34525352 NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions. 2021 Sep 14 4
8 34677384 Drosophila INDY and Mammalian INDY: Major Differences in Transport Mechanism and Structural Features despite Mostly Similar Biological Functions. 2021 Sep 29 2
9 34677420 Molecular Mechanisms of the SLC13A5 Gene Transcription. 2021 Oct 15 2
10 34943889 Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes. 2021 Dec 1 2
11 32444674 The Hepatic Plasma Membrane Citrate Transporter NaCT (SLC13A5) as a Molecular Target for Metformin. 2020 May 22 1
12 32634519 Comparative proteomic analysis of SLC13A5 knockdown reveals elevated ketogenesis and enhanced cellular toxic response to chemotherapeutic agents in HepG2 cells. 2020 Sep 1 2
13 32692565 Cell Metabolomics Reveals Berberine-Inhibited Pancreatic Cancer Cell Viability and Metastasis by Regulating Citrate Metabolism. 2020 Sep 4 1
14 33079129 Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY). 2020 Nov 13 2
15 29410496 Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells. 2018 Feb 6 4
16 30054523 Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism. 2018 Jul 27 2
17 30478052 Citrate-based materials fuel human stem cells by metabonegenic regulation. 2018 Dec 11 2
18 28264506 Plasma Membrane Na⁺-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy. 2017 Feb 28 9
19 28655760 Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells. 2017 Aug 18 3
20 28673551 Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle. 2017 Aug 3
21 28821606 Flipping a citrate switch on liver cancer cells. 2017 Aug 18 1
22 26734723 Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family. 2016 Feb 11 1
23 27069776 Model-Based Assessment of Plasma Citrate Flux Into the Liver: Implications for NaCT as a Therapeutic Target. 2016 Mar 3
24 27683012 Molecular Basis for Inhibition of the Na+/Citrate Transporter NaCT (SLC13A5) by Dicarboxylate Inhibitors. 2016 Dec 2
25 27754898 State-Dependent Allosteric Inhibition of the Human SLC13A5 Citrate Transporter by Hydroxysuccinic Acids, PF-06649298 and PF-06761281. 2016 Dec 2
26 27818933 Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice. 2016 Nov 1
27 25617245 Species-specific influence of lithium on the activity of SLC13A5 (NaCT): lithium-induced activation is specific for the transporter in primates. 2015 Apr 1
28 25628225 SLC13A5 is a novel transcriptional target of the pregnane X receptor and sensitizes drug-induced steatosis in human liver. 2015 Apr 2
29 26303333 Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes. 2015 Nov 4 2
30 26324167 Electrophysiological characterization of human and mouse sodium-dependent citrate transporters (NaCT/SLC13A5) reveal species differences with respect to substrate sensitivity and cation dependence. 2015 Nov 4
31 26384929 Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia. 2015 Nov 1
32 26620127 Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5). 2015 Dec 1 4
33 24995870 Mutations in SLC13A5 cause autosomal-recessive epileptic encephalopathy with seizure onset in the first days of life. 2014 Jul 3 1
34 24688728 The Role of INDY in Metabolic Regulation. 2013 1
35 16973915 Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines. 2007 Jan 1
36 12826022 Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. 2003 Aug 15 2