Aspirin

T cell leukemia homeobox 2 ; Homo sapiens







34 Article(s)
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1 20065114 NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes. 2010 Feb 15 1
2 20299485 Hyperglycemia-induced platelet activation in type 2 diabetes is resistant to aspirin but not to a nitric oxide-donating agent. 2010 Jun 2
3 20608787 Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia. 2010 1
4 19341823 Comparative effects of aspirin and NO-releasing aspirins on differentiation, maturation and function of human monocyte-derived dendritic cells in vitro. 2009 Jul 6
5 18196976 NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts. 2008 Jan 1 2
6 18302761 NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols. 2008 Feb 26 1
7 18472019 NCX 4040, an NO-donating acetylsalicylic acid derivative: efficacy and mechanisms of action in cancer cells. 2008 Sep 2
8 18485921 Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality. 2008 Sep 2
9 18492771 The nitric oxide-donating derivative of acetylsalicylic acid, NCX 4016, stimulates glucose transport and glucose transporters translocation in 3T3-L1 adipocytes. 2008 Jul 2
10 17334512 Prevention by NCX 4016, a nitric oxide-donating aspirin, but not by aspirin, of the acute endothelial dysfunction induced by exercise in patients with intermittent claudication. 2007 Mar 1
11 17760507 Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells. 2007 Nov 1
12 17903525 Nitric oxide-donating aspirin (NCX 4016) inhibits neointimal thickening in a pig model of saphenous vein-carotid artery interposition grafting: a comparison with aspirin and morpholinosydnonimine (SIN-1). 2007 Oct 4
13 17971198 Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines. 2007 Oct 30 2
14 16497833 Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin. 2006 Mar 7 2
15 16961726 Pharmacologic profile and therapeutic potential of NCX 4016, a nitric oxide-releasing aspirin, for cardiovascular disorders. 2006 Summer 3
16 16144976 Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016). 2005 Dec 5
17 14563672 Antioxidant activity of nitro derivative of aspirin against ischemia-reperfusion in hamster cheek pouch microcirculation. 2004 Mar 2
18 14762100 Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence. 2004 Jun 5
19 14762891 Polymorphism of NCX4016, an NO-releasing derivative of acetylsalicylic acid. 2004 Mar 1
20 15240674 Nitric oxide regulates immune cell bioenergetic: a mechanism to understand immunomodulatory functions of nitric oxide-releasing anti-inflammatory drugs. 2004 Jul 15 4
21 15358033 Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. 2004 Aug 4 3
22 12612897 Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. 2003 Mar 2
23 12738997 NCX 4016, a nitric oxide-releasing aspirin derivative, exhibits a significant antiproliferative effect and alters cell cycle progression in human colon adenocarcinoma cell lines. 2003 Jun 3
24 12846439 NO-aspirin: mechanism of action and gastrointestinal safety. 2003 May 5
25 12960371 Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa. 2003 Sep 16 2
26 14582459 NCX-4016 NicOx. 2003 Sep 1
27 12207011 NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function. 2002 Oct 1
28 11447266 NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. 2001 Jul 17 1
29 10968413 The effect of aspirin and two nitric oxide donors on the infarcted heart in situ. 2000 Jul 7 1
30 11046058 IL-1 beta converting enzyme is a target for nitric oxide-releasing aspirin: new insights in the antiinflammatory mechanism of nitric oxide-releasing nonsteroidal antiinflammatory drugs. 2000 Nov 1 1
31 10065898 In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016. 1999 Jan 1 1
32 9435549 Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils. 1997 Dec 1
33 8735820 In vitro study of the anti-aggregating activity of two nitroderivatives of acetylsalicylic acid. 1996 Mar 3
34 8950792 The antiplatelet effects of a new nitroderivative of acetylsalicylic acid--an in vitro study of inhibition on the early phase of platelet activation and on TXA2 production. 1996 Nov 1