| 301 |
18625162 | Direct renin inhibition: an analysis of possible benefits. | 2008 Aug |
2 |
| 302 |
18662494 | Effect of aliskiren, an oral direct renin inhibitor, on the pharmacokinetics and pharmacodynamics of a single dose of acenocoumarol in healthy volunteers. | 2008 Sep |
1 |
| 303 |
18687166 | Direct renin inhibition: an evaluation of the safety and tolerability of aliskiren. | 2008 Sep |
2 |
| 304 |
18695203 | Aliskiren. | 2008 Aug 12 |
1 |
| 305 |
18695389 | Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients? | 2008 Sep |
1 |
| 306 |
18698213 | Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren. | 2008 Sep |
2 |
| 307 |
18704745 | Inhibition of the renin-angiotensin system and chronic kidney disease. | 2008 |
1 |
| 308 |
18764720 | The development of the direct renin inhibitor aliskiren: treating hypertension and beyond. | 2008 Sep |
3 |
| 309 |
18765089 | Now that we have a direct renin inhibitor, what should we do with it? | 2008 Jun |
1 |
| 310 |
18784280 | Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren. | 2008 Nov |
2 |
| 311 |
18786303 | A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects. | 2008 Aug |
2 |
| 312 |
18802783 | First renin inhibitor, aliskiren, for the treatment of hypertension. | 2008 Dec |
2 |
| 313 |
18843743 | Blood pressure lowering efficacy of renin inhibitors for primary hypertension. | 2008 Oct 8 |
1 |
| 314 |
18929229 | Renin inhibitors: novel agents for renoprotection or a better angiotensin receptor blocker for blood pressure lowering? | 2008 Nov |
1 |
| 315 |
18957387 | Effects of the direct renin inhibitor aliskiren and atenolol alone or in combination in patients with hypertension. | 2008 Sep |
2 |
| 316 |
18981317 | Aliskiren accumulates in Renin secretory granules and binds plasma prorenin. | 2008 Dec |
8 |
| 317 |
19035874 | Pharmacokinetic interaction of the direct renin inhibitor aliskiren with furosemide and extended-release isosorbide-5-mononitrate in healthy subjects. | 2008 Winter |
1 |
| 318 |
19051513 | [Aliskiren (Rasilez), direct renin inhibitor]. | 2008 Sep |
2 |
| 319 |
19066408 | Pharmacokinetics and pharmacodynamics of aliskiren, an oral direct renin inhibitor. | 2008 Sep-Oct |
3 |
| 320 |
19183745 | The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction. | 2008 |
1 |
| 321 |
19203020 | Efficacy of aliskiren/hydrochlorothiazide single-pill combinations in aliskiren non-responders. | 2008 Dec |
1 |
| 322 |
19212031 | Aliskiren: a novel renin inhibitor for hypertension. | 2008 Jan-Feb |
2 |
| 323 |
19337534 | Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy. | 2008 |
3 |
| 324 |
19808266 | Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure. | 2008 May |
1 |
| 325 |
23355128 | Cardiovascular risk in hypertension - can we ask for more? : focus on aliskiren. | 2008 Oct |
2 |
| 326 |
17143194 | Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. | 2007 Jan |
3 |
| 327 |
17159081 | Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. | 2007 Feb |
3 |
| 328 |
17198906 | Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan. | 2007 Jan |
2 |
| 329 |
17244770 | Pharmacokinetics, safety, and tolerability of the oral Renin inhibitor aliskiren in patients with hepatic impairment. | 2007 Feb |
2 |
| 330 |
17341529 | Aliskiren for renin inhibition: a new class of antihypertensives. | 2007 Mar |
2 |
| 331 |
17352858 | [Global treatment of cardiovascular risk in the hypertensive patient]. | 2007 Feb |
1 |
| 332 |
17353513 | Direct Renin inhibition with aliskiren in obese patients with arterial hypertension. | 2007 May |
1 |
| 333 |
17376010 | Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution? | 2007 Apr |
2 |
| 334 |
17389554 | Pharmacokinetics, safety, and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects. | 2007 Apr |
1 |
| 335 |
17401311 | Expanding the opportunities for blocking the renin-angiotensin system: introduction to a special supplement. | 2007 |
1 |
| 336 |
17401313 | The efficacy of aliskiren, a direct renin inhibitor, in the treatment of hypertension. | 2007 |
2 |
| 337 |
17485026 | Aliskiren, the first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness. | 2007 May |
6 |
| 338 |
17510248 | Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers. | 2007 Aug |
2 |
| 339 |
17541390 | A comparison of the tolerability of the direct renin inhibitor aliskiren and lisinopril in patients with severe hypertension. | 2007 Oct |
1 |
| 340 |
17578167 | [Does the rennin inhibitor aliskiren offer promising novel opportunities in the treatment of cardiovascular diseases?]. | 2007 Apr |
2 |
| 341 |
17590217 | Plasma renin and the antihypertensive effect of the orally active renin inhibitor aliskiren in clinical hypertension. | 2007 Sep |
2 |
| 342 |
17655373 | Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment. | 2007 |
2 |
| 343 |
17658393 | Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial. | 2007 Jul 21 |
1 |
| 344 |
17673883 | Direct renin inhibitors: a new approach to antihypertensive drug treatment. | 2007 Aug |
1 |
| 345 |
17686379 | Renin inhibition: a new modality for hypertension management. | 2007 Aug |
1 |
| 346 |
17700383 | Direct inhibition of renin as a cardiovascular pharmacotherapy: focus on aliskiren. | 2007 Sep-Oct |
3 |
| 347 |
17702736 | Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals. | 2007 Sep |
3 |
| 348 |
17703126 | Novel drugs targeting hypertension: renin inhibitors. | 2007 Aug |
1 |
| 349 |
17824680 | Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets. | 2007 Oct 4 |
1 |
| 350 |
17867914 | Aliskiren, the future of renin-angiotensin system blockade? | 2007 Sep |
3 |