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34514971 | Interaction of the renin inhibitor aliskiren with the SARS-CoV-2 main protease: a molecular docking study. | 2021 Sep 13 |
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26421414 | Elucidation of the binding mechanism of renin using a wide array of computational techniques and biological assays. | 2015 Nov |
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8613199 | Human renin-dependent hypertension in rats transgenic for human angiotensinogen. | 1996 Mar |
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8730924 | Pharmacokinetics of remikiren, a potent orally active inhibitor of human renin, in rat, dog and primates. | 1996 Mar |
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8783774 | Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system. | 1996 Jun |
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7586899 | Clinical pharmacokinetics and efficacy of renin inhibitors. | 1995 Jul |
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7769797 | Responses to an orally active renin inhibitor, remikiren (Ro 42-5892), after controlled salt depletion in humans. | 1995 Mar |
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7795817 | Determination of the renin inhibitor Ro 42-5892 in human plasma by automated pre-column derivatization, reversed-phase high-performance liquid chromatographic separation and electrochemical detection after post-column irradiation. | 1995 Mar 24 |
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8207739 | Time dependency of the antihypertensive efficacy of the new renin inhibitor Ro 42-5892. | 1994 Feb |
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7678159 | Renin inhibitors as an example of presumptive irrelevant positive findings in the Salmonella/mammalian microsome assay (Ames test). | 1993 Feb |
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8222499 | Efficacy and tolerability of the renin inhibitor Ro 42-5892 in patients with hypertension. | 1993 Nov |
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8228207 | Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension. | 1993 Aug |
2 |
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8512659 | Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension. | 1993 May |
2 |
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12959271 | Multiple dose pharmacokinetics and concentration effect relationship of the orally active renin inhibitor remikiren (Ro 42-5892) in hypertensive patients. | 1993 Dec |
2 |
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1282588 | Neurohormonal and blood pressure responses to low-dose infusion of an orally active renin inhibitor, Ro 42-5892, in salt-replete men. | 1992 Dec |
1 |
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1502199 | Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. | 1992 Aug 15 |
1 |
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1728438 | Blood pressure control by the renin-angiotensin system in normotensive subjects. Assessment by angiotensin converting enzyme and renin inhibition. | 1992 Jan |
1 |
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1720828 | Effect of the renin response during renin inhibition: oral Ro 42-5892 in normal humans. | 1991 Sep |
1 |
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1830563 | Ro 42-5892 is a potent orally active renin inhibitor in primates. | 1991 Jul |
4 |
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1873015 | Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact. | 1991 Jul |
1 |
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1889841 | Renin release regulation during acute renin inhibition in normal volunteers. | 1991 Sep |
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2203486 | Prolonged blood pressure reduction by orally active renin inhibitor RO 42-5892 in essential hypertension. | 1990 Jul 28 |
1 |