| 1 |
34931827 | Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming. | 2022 Jan 13 |
1 |
| 2 |
35122182 | Long noncoding RNA RP11-241J12.3 targeting pyruvate carboxylase promotes hepatocellular carcinoma aggressiveness by disrupting pyruvate metabolism and the DNA mismatch repair system. | 2022 Feb 5 |
2 |
| 3 |
33880999 | Expression of pyruvate carboxylase in cultured human astrocytoma, glioblastoma and neuroblastoma cells. | 2021 Mar |
2 |
| 4 |
33931119 | Pyruvate carboxylase and cancer progression. | 2021 Apr 30 |
2 |
| 5 |
34057673 | Two Metabolic Fuels, Glucose and Lactate, Differentially Modulate Exocytotic Glutamate Release from Cultured Astrocytes. | 2021 Oct |
1 |
| 6 |
34136384 | Value of Pyruvate Carboxylase in Thyroid Fine-Needle Aspiration Wash-Out Fluid for Predicting Papillary Thyroid Cancer Lymph Node Metastasis. | 2021 |
1 |
| 7 |
34150393 | A Unique Case of Pyruvate Carboxylase Deficiency. | 2021 May 15 |
2 |
| 8 |
30949058 | The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans. | 2019 |
1 |
| 9 |
31180060 | Biosynthesis of some organic acids and lipids in industrially important microorganisms is promoted by pyruvate carboxylases. | 2019 Jun |
2 |
| 10 |
31697914 | MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells. | 2019 Nov 30 |
2 |
| 11 |
29643369 | Allosteric regulation alters carrier domain translocation in pyruvate carboxylase. | 2018 Apr 11 |
2 |
| 12 |
30005601 | Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer. | 2018 Jul 13 |
2 |
| 13 |
30045381 | Pyruvate Carboxylase Deficiency Type C: A Rare Cause of Acute Transient Flaccid Paralysis with Ketoacidosis. | 2018 Dec |
2 |
| 14 |
27068034 | Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis. | 2017 Jan |
1 |
| 15 |
27890529 | Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells. | 2017 Feb |
1 |
| 16 |
27254467 | Pyruvate Occupancy in the Carboxyl Transferase Domain of Pyruvate Carboxylase Facilitates Product Release from the Biotin Carboxylase Domain through an Intermolecular Mechanism. | 2016 Jun 21 |
1 |
| 17 |
27732858 | Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis. | 2016 Oct 11 |
3 |
| 18 |
27885626 | Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood. | 2016 |
1 |
| 19 |
25607840 | Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. | 2015 Feb |
2 |
| 20 |
26070193 | Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells. | 2015 |
2 |
| 21 |
28649521 | Pyruvate carboxylase deficiency: An underestimated cause of lactic acidosis. | 2015 Mar |
2 |
| 22 |
24363178 | Regulation of pyruvate metabolism and human disease. | 2014 Jul |
1 |
| 23 |
24476417 | Nearly 50 years in the making: defining the catalytic mechanism of the multifunctional enzyme, pyruvate carboxylase. | 2014 Mar |
1 |
| 24 |
25243911 | Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase. | 2014 |
1 |
| 25 |
23698000 | A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase. | 2013 Jul 5 |
2 |
| 26 |
23098296 | Localization of inhibitory antibodies to the biotin domain of human pyruvate carboxylase. | 2012 Oct |
1 |
| 27 |
21454710 | Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets. | 2011 May 27 |
1 |
| 28 |
21958016 | Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. | 2011 Nov 15 |
1 |
| 29 |
20598931 | Pyruvate carboxylase deficiency: mechanisms, mimics and anaplerosis. | 2010 Sep |
2 |
| 30 |
20807508 | Pyruvate carboxylase is expressed in human skeletal muscle. | 2010 Nov 12 |
2 |
| 31 |
18686030 | Expression of pyruvate carboxylase in cultured oligodendroglial, microglial and ependymal cells. | 2009 Mar |
1 |
| 32 |
18613815 | Structure, mechanism and regulation of pyruvate carboxylase. | 2008 Aug 1 |
1 |
| 33 |
16505973 | Anaplerotic roles of pyruvate carboxylase in mammalian tissues. | 2006 Apr |
2 |
| 34 |
16929648 | Dechlorination of polychlorinated biphenyl congeners by anaerobic microorganisms from river sediment. | 2006 Jul |
2 |
| 35 |
14660628 | Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate-pyruvate shuttle. | 2004 Feb 27 |
1 |
| 36 |
12437512 | Expression and characterization of a human pyruvate carboxylase variant by retroviral gene transfer. | 2003 Feb 15 |
1 |
| 37 |
10229653 | Structure, function and regulation of pyruvate carboxylase. | 1999 May 15 |
2 |
| 38 |
9585002 | Molecular characterization of pyruvate carboxylase deficiency in two consanguineous families. | 1998 May |
1 |
| 39 |
9467236 | Gluconeogenesis in patients with impaired liver function. | 1997 Dec |
3 |
| 40 |
8884571 | Disorders of gluconeogenesis. | 1996 |
1 |
| 41 |
1415529 | On the mechanism of stimulation of ureagenesis by gluconeogenic substrates: role of pyruvate carboxylase. | 1992 Sep |
1 |
| 42 |
1980584 | Synthesis of transmitter glutamate and the glial-neuron interrelationship. | 1990 Jan |
1 |
| 43 |
3091918 | Pyruvate carboxylase defect: metabolic studies on cultured skin fibroblasts. | 1986 |
1 |
| 44 |
3985180 | Determination of gluconeogenesis in vivo with 14C-labeled substrates. | 1985 Apr |
1 |
| 45 |
7362856 | Studies on the formation of phosphoenolpyruvate and citric acid cycle intermediates by neonatal piglet liver mitochondria. | 1980 |
2 |
| 46 |
8990 | Role of oxalacetate in lipoate effect on frog gastric mucosa. | 1976 Jul |
1 |
| 47 |
939224 | Apparent co-operative effect of hydrogen carbonate (HCO-3) on pigeon kidney pyruvate carboxylase. | 1976 |
1 |
| 48 |
1147984 | Pyruvate carboxylase: affinity labelling of the pyruvate binding site. | 1975 Jul 8 |
1 |
| 49 |
19396987 | Transfer of reducing equivalents across the mitochondrial membrane. I. Hydrogen transfer mechanisms involved in the reduction of pyruvate to lactate in isolated liver cells. | 1974 Jan 18 |
2 |
| 50 |
4348015 | Interaction of pyruvate with pyruvate carboxylase and pyruvate kinase as studied by paramagnetic effects on 13 C relaxation rates. | 1973 Feb |
1 |