rofecoxib

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







262 Article(s)
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1 31534549 Prostaglandin E2 induces DNA hypermethylation in gastric cancer in vitro and in vivo. 2019 1
2 29732985 Treatment of Chronic Articular Pain in Adult People with Hemophilia. 2018 1
3 29928230 Can Electronic Health Records Databases Complement Spontaneous Reporting System Databases? A Historical-Reconstruction of the Association of Rofecoxib and Acute Myocardial Infarction. 2018 1
4 30195234 Computer-aided identification of natural lead compounds as cyclooxygenase-2 inhibitors using virtual screening and molecular dynamic simulation. 2018 Dec 1
5 26982261 Deciphering the mechanism behind the varied binding activities of COXIBs through Molecular Dynamic Simulations, MM-PBSA binding energy calculations and per-residue energy decomposition studies. 2017 Mar 1
6 27388291 Causal Inference for Meta-Analysis and Multi-Level Data Structures, with Application to Randomized Studies of Vioxx. 2017 Jun 1
7 28105626 [Effect of polyunsaturated fatty acids ω-3 and ω-6 on angiogenesis formation in human gastric cancer]. 2017 Jan 25 2
8 28375409 Hot Topics in Primary Care: The Cardiovascular Safety of Nonsteroidal Anti-Inflammatory Drugs: Putting the Evidence in Perspective. 2017 Apr 2
9 27324742 Rational Design and Synthesis of Biologically Active Disubstituted 2(3H) Furanones and Pyrrolone Derivatives as Potent and Safer Non Steroidal Anti-inflammatory Agents. 2016 1
10 27537326 Hepatotoxicity induced by coxibs: how concerned should we be? 2016 Nov 1
11 25806762 [Cardiovascular safety of non-steroidal anti-inflammatory drugs]. 2015 Mar 24 1
12 24365321 Nonsteroidal anti-inflammatory drugs exposure and the central nervous system. 2014 2
13 25408841 Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors. 2014 Nov 13 1
14 25559449 Ultrahigh-performance liquid chromatography/tandem mass spectrometry method for evaluating enzyme activity and screening inhibitors of cyclooxygenase-2. 2014 Aug 30 1
15 23031659 Are drug provocation tests still necessary to test the safety of COX-2 inhibitors in patients with cross-reactive NSAID hypersensitivity? 2013 May-Jun 1
16 23441769 How safe is Celecoxib for Asian-Indian patients with rheumatic diseases? 2013 Feb 1
17 23454135 Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes. 2013 May 13 1
18 23580446 Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells. 2013 Jul 1
19 21507199 IL-10 production in non-small cell lung carcinoma patients is regulated by ERK, P38 and COX-2. 2012 Mar 1
20 22002318 A novel nitro-oxy substituted analogue of rofecoxib reduces human colon cancer cell growth. 2012 Feb 2
21 22819703 Phospholipase A₂ activities in skin physiology and pathology. 2012 Sep 15 1
22 21548865 Lipoxins, the novel mediators of gastroprotection and gastric adaptation to ulcerogenic action of aspirin. 2011 2
23 21600026 Using clinical trial data and linked administrative health data to reduce the risk of adverse events associated with the uptake of newly released drugs by older Australians: a model process. 2011 May 21 1
24 21752640 Bioactive sulfoximines: syntheses and properties of Vioxx analogs. 2011 Aug 15 1
25 21830840 Randomized controlled trials of COX-2 inhibitors: an analysis of doses used and trends over time to investigate implications for comparative safety. 2011 Sep 1 1
26 22114865 An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect? 2011 Nov 24 4
27 24250402 Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships. 2011 Fall 1
28 20166930 Progress in COX-2 inhibitors: a journey so far. 2010 1
29 20569079 Cardiovascular safety of non-steroidal anti-inflammatory drugs among healthy individuals. 2010 Nov 1
30 20692174 Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors. 2010 Sep 1 3
31 21373319 Etoricoxib-induced life-threatening hyperkalemia and acute kidney dysfunction against the background of telmisartan and a low sodium diet. 2010 Aug 20 1
32 24825998 Rofecoxib prevents ctdsDNA against damage induced by copper sulfate and ultraviolet B radiation in vitro study. 2010 Dec 2
33 19374865 PPAR activators and COX inhibitors selectively block cytokine-induced COX-2 expression and activity in human aortic smooth muscle cells. 2009 Mar 15 1
34 19530988 Prostaglandin E(2) synthase inhibition as a therapeutic target. 2009 Jul 1
35 17963198 Large-scale stopping and switching treatment with COX-2 inhibitors after the rofecoxib withdrawal. 2008 Jan 1
36 18163459 Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G. 2008 Jul 1
37 18507001 Combination therapy of S-1 with selective cyclooxygenase-2 inhibitor for liver metastasis of colorectal carcinoma. 2008 Mar-Apr 1
38 18541831 Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs and risk of stroke. 2008 Jun 9 1
39 18606461 Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology. 2008 Aug 1
40 18690976 Risk-benefit perspectives in COX-2 blockade. 2008 Jan 2
41 18802217 A postgenomic integrated view of prostaglandins in reproduction: implications for other body systems. 2008 Aug 1
42 19075637 Cyclooxygenase inhibitors: instrumental drugs to understand cardiovascular homeostasis and arterial thrombosis. 2008 Dec 2
43 20046772 A Study on Improvement of Solubility of Rofecoxib and its effect on Permeation of Drug from Topical Formulations. 2008 Jul-Aug 1
44 16645868 [Transient global amnesia (TGA) during an oral provocation test]. 2007 Feb 2
45 17222987 A pathogenetic mechanism for COX-2 inhibitor-induced cardiovascular events proposed to be useful in structuring medical testimony in rofecoxib trials. 2007 1
46 17305573 Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers. 2007 1
47 17316360 Exploring the potential chemopreventative effect of aspirin and rofecoxib on hereditary nonpolyposis colorectal cancer-like endometrial cancer cells in vitro through mechanisms involving apoptosis, the cell cycle, and mismatch repair gene expression. 2007 Mar-Apr 1
48 17387473 Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition. 2007 Oct 1
49 17453399 Selective COX-2 inhibitor versus indomethacin for the prevention of heterotopic ossification after hip replacement: a double-blind randomized trial of 100 patients with 1-year follow-up. 2007 Feb 2
50 17504133 Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. 2007 2