| 1 |
30663092 | Access to 18 F-labelled isoxazoles by ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18 F]fluoro-N-hydroxybenzimidoyl chloride with alkynes. | 2019 Jun 30 |
1 |
| 2 |
29502024 | Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy. | 2018 Apr |
1 |
| 3 |
30108944 | Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity. | 2018 Mar 1 |
1 |
| 4 |
30288211 | Correction: Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity. | 2018 Mar 1 |
1 |
| 5 |
26982261 | Deciphering the mechanism behind the varied binding activities of COXIBs through Molecular Dynamic Simulations, MM-PBSA binding energy calculations and per-residue energy decomposition studies. | 2017 Mar |
1 |
| 6 |
27354402 | Valdecoxib Recovers the Lipid Composition, Order and Dynamics in Colon Cancer Cell Lines Independent of COX-2 Expression: An ATR-FTIR Spectroscopy Study. | 2017 Jan |
2 |
| 7 |
27537326 | Hepatotoxicity induced by coxibs: how concerned should we be? | 2016 Nov |
1 |
| 8 |
25770423 | Activating PTEN by COX-2 inhibitors antagonizes radiation-induced AKT activation contributing to radiosensitization. | 2015 May 1 |
1 |
| 9 |
25946000 | Drug repositioning for diabetes based on 'omics' data mining. | 2015 |
1 |
| 10 |
26130144 | Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury. | 2015 Jul 1 |
1 |
| 11 |
26183281 | A standardized and reproducible protocol for serum-free monolayer culturing of primary paediatric brain tumours to be utilized for therapeutic assays. | 2015 Jul 17 |
1 |
| 12 |
23984829 | Drug analogs of COX-2 selective inhibitors lumiracoxib and valdecoxib derived from in silico search and optimization. | 2014 Mar |
2 |
| 13 |
24365321 | Nonsteroidal anti-inflammatory drugs exposure and the central nervous system. | 2014 |
2 |
| 14 |
24431307 | The effect of valdecoxib on the production of growth factors evoked by hypoxia and bacterial lipopolysaccharide in HMEC-1 cells. | 2013 Nov-Dec |
1 |
| 15 |
24570829 | Synthesis, Anti-Inflammatory and Anti- Nociceptive Activities and Cytotoxic Effect of Novel Thiazolidin-4-ones Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors. | 2013 Dec |
1 |
| 16 |
22130459 | Pharmacokinetics of intravenous and intramuscular parecoxib in healthy Beagles. | 2012 Jul |
1 |
| 17 |
20699408 | Reduction of N-hydroxy-sulfonamides, including N-hydroxy-valdecoxib, by the molybdenum-containing enzyme mARC. | 2010 Nov |
3 |
| 18 |
19563267 | The search for new COX-2 inhibitors: a review of 2002 - 2008 patents. | 2009 Sep |
1 |
| 19 |
19578771 | The regulatory effect of the p38 signaling pathway on valdecoxib-induced apoptosis of the Eca109 cell line. | 2009 Aug |
1 |
| 20 |
18171312 | Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs. | 2008 Jan |
2 |
| 21 |
18353655 | Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib. | 2008 May 1 |
1 |
| 22 |
18802217 | A postgenomic integrated view of prostaglandins in reproduction: implications for other body systems. | 2008 Aug |
1 |
| 23 |
17305573 | Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers. | 2007 |
1 |
| 24 |
17397743 | Successful treatment of cystoid macular edema with valdecoxib. | 2007 Apr |
3 |
| 25 |
17504133 | Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. | 2007 |
1 |
| 26 |
17525166 | Utility and sensitivity of the sore throat pain model: results of a randomized controlled trial on the COX-2 selective inhibitor valdecoxib. | 2007 Jul |
1 |
| 27 |
17661262 | [Cardiovascular toxicity of selective COX-2-inhibitors and classical NSAIDs]. | 2007 Jul |
2 |
| 28 |
19075973 | Targeting inhibition of COX-2: a review of patents, 2002-2006. | 2007 Jun |
1 |
| 29 |
16476920 | The COX-2 specific inhibitor Valdecoxib versus tramadol in acute ankle sprain: a multicenter randomized, controlled trial. | 2006 Jun |
1 |
| 30 |
16519515 | Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. | 2006 Mar 14 |
2 |
| 31 |
16529650 | Effect of valdecoxib pretreatment on pain and secondary hyperalgesia: a randomized controlled trial in healthy volunteers [ISRCTN05282752, NCT00260325]. | 2006 Mar 10 |
1 |
| 32 |
16599270 | Determination of valdecoxib in serum using a HPLC-diode array detector and its application in a pharmacokinetic study. | 2006 Mar |
1 |
| 33 |
16618816 | Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction. | 2006 Apr 25 |
1 |
| 34 |
15494548 | Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity. | 2005 Mar |
8 |
| 35 |
15713945 | Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. | 2005 Mar 17 |
1 |
| 36 |
15887009 | The effect of mild and moderate hepatic impairment on the pharmacokinetics of valdecoxib, a selective COX-2 inhibitor. | 2005 Jun |
1 |
| 37 |
15974940 | Impact of COX-2 inhibitors in common clinical practice a gastroenterologist's perspective. | 2005 |
1 |
| 38 |
16083531 | Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray? | 2005 Aug |
1 |
| 39 |
16178945 | Valdecoxib for treatment of a single, acute, moderate to severe migraine headache. | 2005 Oct |
1 |
| 40 |
16180941 | Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors. | 2005 |
2 |
| 41 |
16311613 | Increased risk of cardiovascular events with parecoxib/valdecoxib: a systematic review and meta-analysis. | 2005 Nov 25 |
1 |
| 42 |
14698154 | Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. | 2004 Jan 19 |
1 |
| 43 |
14965322 | Clinical pharmacology of novel selective COX-2 inhibitors. | 2004 |
1 |
| 44 |
15039937 | Collision-induced dissociation of valdecoxib metabolites: a novel rearrangement involving an isoxazole ring. | 2004 Mar |
1 |
| 45 |
15050982 | Cyclooxygenase-2 specific inhibitors in the treatment of dysmenorrhea. | 2004 Apr |
2 |
| 46 |
15117884 | Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. | 2004 May |
1 |
| 47 |
15124935 | Selective cyclooxygenase-2 inhibitors: similarities and differences. | 2004 |
2 |
| 48 |
15161329 | Valdecoxib: a review of its use in the management of osteoarthritis, rheumatoid arthritis, dysmenorrhoea and acute pain. | 2004 |
2 |
| 49 |
15182039 | [Valdecoxib (Bextra)]. | 2004 Apr |
2 |
| 50 |
15266215 | Effects of the cyclooxygenase-2 specific inhibitor valdecoxib versus nonsteroidal antiinflammatory agents and placebo on cardiovascular thrombotic events in patients with arthritis. | 2004 Jul-Aug |
1 |