Celecoxib

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







676 Article(s)
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1 34080112 New ursolic acid derivatives bearing 1,2,3-triazole moieties: design, synthesis and anti-inflammatory activity in vitro and in vivo. 2022 Apr 1
2 34376069 Gastrointestinal and cardiovascular adverse events associated with NSAIDs. 2022 Mar 1
3 34514981 The Role of Celecoxib as a Potential Inhibitor in the Treatment of Inflammatory Diseases - A Review. 2022 2
4 34631154 Continuous flow synthesis of Celecoxib from 2-bromo-3,3,3-trifluoropropene. 2022 1
5 34688374 Neoadjuvant PD-1 blockade with toripalimab, with or without celecoxib, in mismatch repair-deficient or microsatellite instability-high, locally advanced, colorectal cancer (PICC): a single-centre, parallel-group, non-comparative, randomised, phase 2 trial. 2022 Jan 1
6 34959176 Anti-inflammatory, ulcerogenic and platelet activation evaluation of novel 1,4-diaryl-1,2,3-triazole neolignan-celecoxib hybrids. 2022 Feb 2
7 35065465 Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity, ulcerogenic liability, ADME profiling and docking study. 2022 Mar 1
8 35105633 Celecoxib versus placebo as an adjunct to treatment-as-usual in children and youth with obsessive-compulsive disorder: protocol for a single-site randomised quadruple-blind phase II study. 2022 Jan 31 1
9 35136486 PACER lncRNA regulates COX-2 expression in lung cancer cells. 2022 1
10 35234840 Cardiorenal Risk of Celecoxib compared to Naproxen, or Ibuprofen in Arthritis Patients: Insights from the PRECISION trial. 2022 Mar 2 1
11 35373257 The Importance of Drug Concentration at the Site of Action: Celecoxib and Colon Polyp Prevention as a Case Study. 2022 Apr 1 1
12 35389917 Meloxicam versus Celecoxib for Postoperative Analgesia after Total Knee Arthroplasty: Safety, Efficacy and Cost. 2022 Apr 5 1
13 35453005 Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features. 2022 Jun 1
14 35585779 Lessons from 20 years with COX-2 inhibitors: importance of dose-response considerations and fair play in comparative trials. 2022 May 18 1
15 33040178 Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid. 2021 Feb 1
16 33244799 Design, synthesis, biological evaluation, and docking studies of some novel chalcones as selective COX-2 inhibitors. 2021 Mar 1
17 33400072 2,5-Dimethyl Celecoxib Inhibits Proliferation and Cell Cycle and Induces Apoptosis in Glioblastoma by Suppressing CIP2A/PP2A/Akt Signaling Axis. 2021 Aug 1
18 33489855 Celecoxib induces apoptosis through Akt inhibition in 5-fluorouracil-resistant gastric cancer cells. 2021 Jan 6
19 33618245 Aspirin and celecoxib may help to rectify a neurotransmission imbalance in bipolar disorder. 2021 Apr 3
20 33667839 Piperine and Celecoxib synergistically inhibit colon cancer cell proliferation via modulating Wnt/β-catenin signaling pathway. 2021 Apr 2
21 33813964 Non-ulcerogenic pyrazolyl 2-hydroxychalcones and pyrazolylpyrazolines derived from naturally existing furochromone (khellin): semi-synthesis, docking study and anti-inflammatory activity. 2021 Apr 5 2
22 33878358 Synthesis, characterization, anti-inflammatory and anti-Helicobacter pylori activities of novel benzophenone tetracarboxylimide benzoyl thiourea cross-linked chitosan hydrogels. 2021 Jun 30 1
23 34052736 Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies. 2021 Aug 2
24 34093801 MicroRNA-30a-3p acts as a tumor suppressor in MHCC-97H hepatocellular carcinoma cells by targeting COX-2. 2021 1
25 34110482 Production, structural and biochemical characterization relevant to antitumor property of acidic exopolysaccharide produced from Bacillus sp. NRC5. 2021 Sep 1
26 34122428 Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy. 2021 1
27 34168004 Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma. 2021 Jun 1
28 34216690 Intracellular AGR2 transduces PGE2 stimuli to promote epithelial-mesenchymal transition and metastasis of colorectal cancer. 2021 Oct 10 1
29 34262619 Efficacy and safety of celecoxib combined with JOINS in the treatment of degenerative knee osteoarthritis: study protocol of a randomized controlled trial. 2021 1
30 34264123 Celecoxib repurposing in cancer therapy: molecular mechanisms and nanomedicine-based delivery technologies. 2021 Aug 1
31 34280124 A positive COX-2/IL-1β loop promotes decidualization by upregulating CD82. 2021 Aug 11 1
32 34303896 Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes. 2021 Oct 1
33 34304363 Physiologically based pharmacokinetic (PBPK) modeling for prediction of celecoxib pharmacokinetics according to CYP2C9 genetic polymorphism. 2021 Jul 1
34 34338135 Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities. 2021 Dec 1
35 34428217 Physiologically relevant aspirin concentrations trigger immunostimulatory cytokine production by human leukocytes. 2021 1
36 34445685 A Combination of Celecoxib and Glucosamine Sulfate Has Anti-Inflammatory and Chondroprotective Effects: Results from an In Vitro Study on Human Osteoarthritic Chondrocytes. 2021 Aug 20 1
37 34447267 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Tolerability, and Safety of Celecoxib Oral Solution (ELYXYB) in Acute Treatment of Episodic Migraine with or without Aura. 2021 1
38 34721382 Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. 2021 1
39 34813026 Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease. 2021 Dec 1
40 31982653 Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors. 2020 Mar 1 3
41 32013633 Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study. 2020 Dec 1
42 32088417 Development of celecoxib-derived antifungals for crop protection. 2020 Apr 1
43 32127262 Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes. 2020 Apr 1 2
44 32208383 Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze. 2020 Apr 9 1
45 32251635 Structural investigation on the selective COX-2 inhibitors mediated cardiotoxicity: A review. 2020 Jun 15 1
46 32468468 Synthesis, Molecular Docking Studies and Biological Evaluation of N-Acylarylhydrazones as Anti-Inflammatory Agents. 2020 1
47 32546278 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway. 2020 Jun 16 1
48 32589073 Comparison of the efficacy and safety of CELBESTA® versus CELEBREX® in patients with rheumatoid arthritis: a 6-week, multicenter, double-blind, double-dummy, active-controlled, randomized, parallel-group, non-inferiority phase 4 clinical trial. 2020 Jun 1
49 32596281 Employment of Alginate Floating In Situ Gel for Controlled Delivery of Celecoxib: Solubilization and Formulation Studies. 2020 2
50 32618021 Anti-inflammatory and analgesic effect of LD-RT and some novel thiadiazole derivatives through COX-2 inhibition. 2020 Oct 1