Arachidonic Acid

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







183 Article(s)
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1 34893997 Development of methylated cobalt-alkyne complexes with selective cytotoxicity against COX-positive cancer cell lines. 2022 Feb 1
2 35175765 Synthesis, Biological Evaluation, and Molecular Docking Study of 3-Amino and 3-Hydroxy-seco A Derivatives of α-Amyrin and 3-Epilupeol as Inhibitors of COX-2 Activity and NF-kB Activation. 2022 Apr 22 1
3 32942970 Natural COX-2 Inhibitors as Promising Anti-inflammatory Agents: An Update. 2021 1
4 33773784 Trans triacylglycerols from dairy products and industrial hydrogenated oil exhibit different effects on the function of human umbilical vein endothelial cells via modulating phospholipase A2/arachidonic acid metabolism pathways. 2021 Jun 2
5 34310861 Kidney damage from nonsteroidal anti-inflammatory drugs-Myth or truth? Review of selected literature. 2021 Aug 1
6 31302749 Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration. 2020 Mar 1
7 32599361 The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen. 2020 Aug 1
8 33033709 15-Deoxy-Δ12,14-prostaglandin J2 Induces Epithelial-to-mesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation. 2020 Sep 30 1
9 30096040 Residual cyclooxygenase activity of aspirin-acetylated COX-2 forms 15 R-prostaglandins that inhibit platelet aggregation. 2019 Jan 3
10 30384258 Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA. 2019 Jan 1
11 30971474 Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2. 2019 Jul 1 2
12 31562623 Aspects of Prostaglandin Glycerol Ester Biology. 2019 1
13 29308820 Kinetic basis for the activation of human cyclooxygenase-2 rather than cyclooxygenase-1 by nitric oxide. 2018 Jan 31 2
14 29408043 Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease. 2018 Apr 1
15 29928483 miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells. 2018 Jun 1 1
16 30151381 Chemical Constituents, Antioxidant, Cyclooxygenase Inhibitor, and Cytotoxic Activities of Teucrium pruinosum Boiss. Essential Oil. 2018 1
17 30314310 Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature. 2018 Oct 11 1
18 30315753 Two-pronged approach to anti-inflammatory therapy through the modulation of the arachidonic acid cascade. 2018 Dec 1
19 30374304 Analgesic Activity, Chemical Profiling and Computational Study on Chrysopogon aciculatus. 2018 1
20 28586004 COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway. 2017 Aug 1
21 28781793 Activation of the arachidonic acid metabolic pathway and induction of sleep disturbance by sacral osteoblastoma: A case report. 2017 Aug 1
22 26632201 Possible effects of repeated exposure to ibuprofen and acetaminophen on the intestinal immune response in young infants. 2016 Feb 2
23 26928048 Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase. 2016 Mar 1
24 27059979 Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2. 2016 Jun 1
25 27111555 COX-1 Inhibitors: Beyond Structure Toward Therapy. 2016 Jul 1
26 27177970 Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. 2016 Aug 1 1
27 27245906 Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. 2016 1
28 27368132 Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs. 2016 Aug 1
29 27768866 Adding Lyso-Lipids to Arachidonate Metabolism Sets the Stage for New Biology. 2016 Oct 20 1
30 27794413 Prostaglandin E Receptor EP4 expression, survival and pattern of recurrence in locally advanced NSCLC. 2016 Nov 1
31 25654274 Candida parapsilosis produces prostaglandins from exogenous arachidonic acid and OLE2 is not required for their synthesis. 2015 1
32 25676325 Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles. 2015 1
33 25734181 Drug repositioning for gynecologic tumors: a new therapeutic strategy for cancer. 2015 1
34 25980490 The role of cyclooxygenase-2 and prostaglandin E2 in the pathogenesis of cutaneous lichen planus. 2015 Dec 1
35 24337484 Butein induces cell apoptosis and inhibition of cyclooxygenase‑2 expression in A549 lung cancer cells. 2014 Feb 1
36 24503478 Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs. 2014 Mar 15 1
37 25047043 Regulation of COX-2 expression by miR-146a in lung cancer cells. 2014 Sep 1
38 23321929 Cyclooxygenase-2 generates the endogenous mutagen trans-4-hydroxy-2-nonenal in Enterococcus faecalis-infected macrophages. 2013 Mar 2
39 23505121 COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons. 2013 Jun 1
40 23682075 Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. 2013 Jul 2
41 24101387 The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid. 2013 Aug 1
42 21655952 Functional polymorphism of cyclooxygenase-2 gene (G-765C) in chronic obstructive pulmonary disease patients. 2012 Mar 1
43 22068350 COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes. 2012 Jan 2
44 22263894 Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. 2012 Mar 8 1
45 22822059 Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets. 2012 Sep 14 1
46 22934333 [Expressions of EOS and COX-2 in nasal polyps in patients with aspirin triad syndrome and its significance]. 2012 Jun 1
47 20817448 Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. 2011 Jan 5 1
48 20868723 Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications. 2011 Jan 1
49 21181286 COX-2 inhibition and inhibition of cytosolic phospholipase A2 increase CD36 expression and foam cell formation in THP-1 cells. 2011 Feb 1
50 21214962 COX-2 expression in papillary thyroid carcinoma (PTC) in cytological material obtained by fine needle aspiration biopsy (FNAB). 2011 Jan 10 1