Diclofenac

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







56 Article(s)
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1 35159907 Biomimetic Citrate-Coated Luminescent Apatite Nanoplatforms for Diclofenac Delivery in Inflammatory Environments. 2022 Feb 6 3
2 35585779 Lessons from 20 years with COX-2 inhibitors: importance of dose-response considerations and fair play in comparative trials. 2022 May 18 1
3 33813964 Non-ulcerogenic pyrazolyl 2-hydroxychalcones and pyrazolylpyrazolines derived from naturally existing furochromone (khellin): semi-synthesis, docking study and anti-inflammatory activity. 2021 Apr 5 1
4 33964802 New nitric oxide-releasing indomethacin derivatives with 1,3-thiazolidine-4-one scaffold: Design, synthesis, in silico and in vitro studies. 2021 Jul 2
5 34182020 Recategorization of Non-Aspirin Nonsteroidal Anti-inflammatory Drugs According to Clinical Relevance: Abandoning the Traditional NSAID Terminology. 2021 Nov 1
6 34568119 Safe and appropriate use of diclofenac in chronic kidney disease: An Indian perspective. 2021 Jul 1
7 31878864 Pro- and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-Methanones as a Novel Inflammation Medication. 2020 1
8 31916080 Coronary Risks Associated with Diclofenac and Other NSAIDs: An Update. 2020 Apr 1
9 31985369 Inhibition of Cyclooxygenase Enzyme by Bioflavonoids in Horsegram Seeds Alleviates Pain and Inflammation. 2020 1
10 28179185 The use of diclofenac sodium in urological practice: A structural and neurochemical based review. 2018 Jan 4
11 28870762 Peripheral nerve and diclofenac sodium: Molecular and clinical approaches. 2018 Jan 2
12 29235601 Ruthenium(ii) arene NSAID complexes: inhibition of cyclooxygenase and antiproliferative activity against cancer cell lines. 2018 Jan 2 2
13 29238904 Anti-inflammatory activity of anti-hyperlipidemic drug, fenofibrate, and its phase-I metabolite fenofibric acid: in silico, in vitro, and in vivo studies. 2018 Aug 1
14 30083389 Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations. 2018 1
15 26823679 Repurposing Drugs in Oncology (ReDO)-diclofenac as an anti-cancer agent. 2016 1
16 27014880 Spinal antinflammatory action of Diclofenac. 2016 Jun 1
17 27548780 Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac. 2016 1
18 27687548 NSAIDs diclofenac, indomethacin, and meloxicam highly upregulate expression of ICAM-1 and COX-2 induced by X-irradiation in human endothelial cells. 2016 Oct 28 3
19 27831630 Safety and efficacy of low doses of diclofenac on acute pain in the emergency setting. 2016 Oct 2
20 24796327 Pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs in retinochoroidal tissues in rabbits. 2014 1
21 25378670 Preadmission use of nonaspirin nonsteroidal anti-inflammatory drugs and 30-day stroke mortality. 2014 Nov 25 2
22 23289871 Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model. 2013 Jan 5 7
23 20817448 Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. 2011 Jan 5 1
24 21830840 Randomized controlled trials of COX-2 inhibitors: an analysis of doses used and trends over time to investigate implications for comparative safety. 2011 Sep 1 1
25 22091869 Binding of ibuprofen, ketorolac, and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR. 2011 Dec 22 3
26 19841157 Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. 2010 Jan 2
27 20092437 A Review on the risk of myocardial infarction associated with the NSAID diclofenac. 2010 Mar 3
28 20237495 Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP. 2010 Aug 1
29 20470236 Diclofenac: an update on its mechanism of action and safety profile. 2010 Jul 1
30 20631416 Vane's discovery of the mechanism of action of aspirin changed our understanding of its clinical pharmacology. 2010 May-Jun 1
31 20648923 In vitro anti-proliferative effects of the willow bark extract STW 33-I. 2010 1
32 21056807 Platelet function following administration of a novel formulation of intravenous diclofenac sodium versus active comparators: a randomized, single dose, crossover study in healthy male volunteers. 2010 Nov 1
33 19602986 Variability in the response to cyclooxygenase inhibitors: toward the individualization of nonsteroidal anti-inflammatory drug therapy. 2009 Aug 1
34 20096163 Field treatment of actinic keratoses - focus on COX-2-inhibitors. 2009 Dec 1
35 18434566 Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. 2008 Jun 1
36 18674517 Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo. 2008 Sep 15 1
37 17164136 Pharmacodynamic of cyclooxygenase inhibitors in humans. 2007 Jan 3
38 17965743 Antagonism of thromboxane receptors by diclofenac and lumiracoxib. 2007 Dec 1
39 18605234 Comparison of antinociceptive efficacy and gastroprotection between celecoxib and diclofenac plus misoprostol in rats. 2007 1
40 16934053 The effect of the withdrawal of rofecoxib on prescribing patterns of COX-2 inhibitors in Scotland. 2006 Sep 1
41 15133778 Drug switching patterns among patients with rheumatoid arthritis and osteoarthritis using COX-2 specific inhibitors and non-specific NSAIDs. 2004 May 1
42 15555544 Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1). 2004 Dec 24 1
43 12534640 Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. 2003 Jan 1
44 12852704 Valdecoxib: a review. 2003 Mar 1
45 12966366 Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac. 2003 Sep 3
46 14655004 [Clinical pharmacology of the selective COX-2 inhibitors]. 2003 Dec 1
47 11874389 Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use. 2002 Mar 3
48 11556519 In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators. 2001 Aug 1
49 11742186 Gastro-duodenal protection in an era of cyclo-oxygenase-2-selective nonsteroidal anti-inflammatory drugs. 2001 Dec 1
50 11028250 Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. 2000 Oct 1