nimesulide

mitochondrially encoded cytochrome c oxidase II ; Homo sapiens







114 Article(s)
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1 33244799 Design, synthesis, biological evaluation, and docking studies of some novel chalcones as selective COX-2 inhibitors. 2021 Mar 1
2 34077833 New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects. 2021 Oct 5 2
3 34354940 Can Nimesulide Nanoparticles Be a Therapeutic Strategy for the Inhibition of the KRAS/PTEN Signaling Pathway in Pancreatic Cancer? 2021 1
4 34575442 Effects of Eye Drops Containing Hyaluronic Acid-Nimesulide Conjugates in a Benzalkonium Chloride-Induced Experimental Dry Eye Rabbit Model. 2021 Aug 30 1
5 29728874 Antineoplastic influence of nimesulide in chemically induced hepatocellular carcinoma by inhibition of DNA synthesis. 2019 Feb 1
6 30689999 The relatively selective cyclooxygenase-2 inhibitor nimesulide: What's going on? 2019 Apr 5 2
7 31095963 Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: Suggested role of prostaglandins. 2019 Sep 1
8 29896263 Nimesulide inhibits proliferation and induces apoptosis of pancreatic cancer cells by enhancing expression of PTEN. 2018 Jul 2
9 27007742 Comparative Evaluation of Nimesulide-Loaded Nanoparticles for Anticancer Activity Against Breast Cancer Cells. 2017 Feb 1
10 27177092 Effects of pro-inflammatory cytokines, lipopolysaccharide and COX-2 mediators on human colonic neuromuscular function and epithelial permeability. 2016 Jul 1
11 25483152 miR-26b is downregulated in human tongue squamous cell carcinoma and regulates cell proliferation and metastasis through a COX-2-dependent mechanism. 2015 Feb 1
12 25724470 Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway. 2015 Jun 3
13 24440378 N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism. 2014 Mar 3 1
14 23031659 Are drug provocation tests still necessary to test the safety of COX-2 inhibitors in patients with cross-reactive NSAID hypersensitivity? 2013 May-Jun 1
15 23645839 AML1-ETO mediates hematopoietic self-renewal and leukemogenesis through a COX/β-catenin signaling pathway. 2013 Jun 13 1
16 22451531 Quantification of nimesulide in human plasma by high-performance liquid chromatography with ultraviolet detector (HPLC-UV): application to pharmacokinetic studies in 28 healthy Korean subjects. 2012 May 1
17 22849544 Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092). 2012 Oct 1
18 21491446 Phase transformation in conformational polymorphs of nimesulide. 2011 Jun 1
19 21542630 Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase. 2011 May 26 2
20 21807508 Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76. 2011 Sep 15 2
21 21980345 Targeting KSHV/HHV-8 latency with COX-2 selective inhibitor nimesulide: a potential chemotherapeutic modality for primary effusion lymphoma. 2011 1
22 21030939 [Nimesulide: 25 years later]. 2010 Aug 3
23 21176579 [Nimesulide induced apoptosis and inhibited metastasis of hypopharyngeal carcinoma cells]. 2010 Oct 3
24 19046800 Nimesulide inhibits IFN-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells by COX-2 and PGE2 independent mechanisms. 2009 Apr 8 2
25 19360361 Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3. 2009 May 1
26 19791801 Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors. 2009 Oct 8 1
27 19854050 Lead optimization of COX-2 inhibitor nimesulide analogs to overcome aromatase inhibitor resistance in breast cancer cells. 2009 Dec 1 2
28 18090373 Effects of aspirin, nimesulide, and SC-560 on vasopressin-induced contraction of human gastroepiploic artery and saphenous vein. 2008 Jan 2
29 18271519 Novel sulfonanilide analogs decrease aromatase activity in breast cancer cells: synthesis, biological evaluation, and ligand-based pharmacophore identification. 2008 Mar 13 1
30 18329216 Spectrophotometric monitoring of nimesulide photodegradation by a combined hard-soft multivariate curve resolution-alternative least square method. 2008 Jul 15 1
31 18581209 Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line. 2008 Sep 1
32 17164136 Pharmacodynamic of cyclooxygenase inhibitors in humans. 2007 Jan 1
33 17226071 Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol. 2007 Feb 1
34 17380299 The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture. 2007 Mar 1
35 17431384 Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells. 2007 Mar 3
36 17485013 Aspirin and COX-2 inhibitor nimesulide potentiate adrenergic contractions of human gastroepiploic artery. 2007 May 4
37 17613921 Risk of upper gastrointestinal events with the use of various NSAIDs: a case-control study in a general population. 2007 Aug 1
38 17878525 Molecular analysis of xenograft models of human cancer cachexia--possibilities for therapeutic intervention. 2007 May-Jun 1
39 23392785 The impact of recent data on our understanding of the roles of COX-1 and COX-2 in gastrointestinal pathophysiology. 2007 Dec 1
40 23392786 Are there any differences among non-steroidal anti-inflammatory drugs? Focus on nimesulide. 2007 Dec 1
41 16331303 Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease. 2006 Feb 2
42 16376453 COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals. 2006 Mar 1
43 16391822 The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells. 2006 Feb 1
44 16469680 Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. 2006 Feb 1
45 16712451 The use of nimesulide and its analogues in cancer chemoprevention. 2006 May 1
46 16846549 Nimesulide -- a multifactorial approach to inflammation and pain: scientific and clinical consensus. 2006 Jun 2
47 17030482 Structure-based pharmacophore of COX-2 selective inhibitors and identification of original lead compounds from 3D database searching method. 2006 Dec 1
48 17154669 Use of nonsteroidal anti-inflammatory drugs in patients with aspirin hypersensitivity : safety of cyclo-oxygenase-2 inhibitors. 2006 1
49 15825163 COX-2 inhibitors suppress integrin alpha5 expression in human lung carcinoma cells through activation of Erk: involvement of Sp1 and AP-1 sites. 2005 Sep 10 1
50 15892673 The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. 2005 1