| 1 |
34370644 | Design and Synthesis of Novel Ibuprofen Derivatives as Selective COX-2 Inhibitors and Potential Anti-Inflammatory Agents: Evaluation of PGE2, TNF-α, IL-6 and Histopathological Study. | 2022 |
2 |
| 2 |
35585779 | Lessons from 20 years with COX-2 inhibitors: importance of dose-response considerations and fair play in comparative trials. | 2022 May 18 |
1 |
| 3 |
33244799 | Design, synthesis, biological evaluation, and docking studies of some novel chalcones as selective COX-2 inhibitors. | 2021 Mar |
1 |
| 4 |
33820460 | Ibuprofen-based advanced therapeutics: breaking the inflammatory link in cancer, neurodegeneration, and diseases. | 2021 Feb |
1 |
| 5 |
34182020 | Recategorization of Non-Aspirin Nonsteroidal Anti-inflammatory Drugs According to Clinical Relevance: Abandoning the Traditional NSAID Terminology. | 2021 Nov |
1 |
| 6 |
34338135 | Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities. | 2021 Dec |
2 |
| 7 |
31016540 | Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials. | 2020 Jan |
1 |
| 8 |
32528119 | Ibuprofen mediates histone modification to diminish cancer cell stemness properties via a COX2-dependent manner. | 2020 Sep |
2 |
| 9 |
30737317 | A seven-step plan for becoming a moderately rich and famous biochemist. | 2019 Feb 8 |
1 |
| 10 |
30885661 | Spectrometric Smartphone-Based System for Ibuprofen Quantification in Commercial Dosage Tablets. | 2019 Aug |
1 |
| 11 |
30991684 | In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity. | 2019 Apr 15 |
1 |
| 12 |
28115830 | Pharmacokinetic and pharmacodynamic evaluation according to absorption differences in three formulations of ibuprofen. | 2017 |
2 |
| 13 |
28153724 | Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing. | 2017 Mar 18 |
1 |
| 14 |
27059979 | Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2. | 2016 Jun |
1 |
| 15 |
27601438 | Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis. | 2016 Dec |
3 |
| 16 |
25463020 | The structure of ibuprofen bound to cyclooxygenase-2. | 2015 Jan |
2 |
| 17 |
26004413 | Beyond COX-inhibition: 'side-effects' of ibuprofen on neoplastic development and progression. | 2015 |
1 |
| 18 |
24243443 | Synthesis and evaluation of 2-(2-arylmorpholino)ethyl esters of ibuprofen hydrochlorides as COX-2 and serotonin reuptake inhibitors. | 2014 Feb |
1 |
| 19 |
23163543 | Ibuprofen: from invention to an OTC therapeutic mainstay. | 2013 Jan |
1 |
| 20 |
23668350 | Structural modeling and simulation studies of human cyclooxygenase (COX) isozymes with selected terpenes: implications in drug designing and development. | 2013 Jul |
1 |
| 21 |
24089379 | Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment. | 2013 Dec |
1 |
| 22 |
22844609 | Vaginal use of Ibuprofen isobutanolammonium (ginenorm): efficacy, tolerability, and pharmacokinetic data: a review of available data. | 2012 |
1 |
| 23 |
23086696 | Characteristics and clinical implications of the pharmacokinetic profile of ibuprofen in patients with knee osteoarthritis. | 2012 Dec |
1 |
| 24 |
21696706 | Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia-ischemia in the immature rodent brain. | 2011 Jul 21 |
1 |
| 25 |
22091869 | Binding of ibuprofen, ketorolac, and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR. | 2011 Dec 22 |
3 |
| 26 |
19345936 | Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells. | 2009 |
1 |
| 27 |
19563267 | The search for new COX-2 inhibitors: a review of 2002 - 2008 patents. | 2009 Sep |
1 |
| 28 |
19949916 | Ibuprofen: pharmacology, efficacy and safety. | 2009 Dec |
1 |
| 29 |
18697608 | Antiatherosclerotic activity of ibuprofen, a non-selective COX inhibitor--an animal study. | 2008 Jun |
2 |
| 30 |
19075973 | Targeting inhibition of COX-2: a review of patents, 2002-2006. | 2007 Jun |
1 |
| 31 |
16519515 | Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. | 2006 Mar 14 |
2 |
| 32 |
16730702 | Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. | 2006 Jul 1 |
2 |
| 33 |
16934053 | The effect of the withdrawal of rofecoxib on prescribing patterns of COX-2 inhibitors in Scotland. | 2006 Sep |
1 |
| 34 |
15736048 | Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression. | 2005 Apr |
1 |
| 35 |
16083531 | Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray? | 2005 Aug |
1 |
| 36 |
14510637 | Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms. | 2004 Feb 1 |
2 |
| 37 |
15013005 | Synthesis and evaluation of S-4-(3-thienyl)phenyl-alpha-methylacetic acid. | 2004 Feb 23 |
1 |
| 38 |
15506544 | Ibuprofen and Alzheimer's disease. | 2004 |
1 |
| 39 |
15555544 | Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1). | 2004 Dec 24 |
2 |
| 40 |
12445672 | Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana. | 2003 Jan 10 |
1 |
| 41 |
12608645 | CD40 ligation triggers COX-2 expression in endothelial cells: evidence that CD40-mediated IL-6 synthesis is COX-2-dependent. | 2003 Jan |
1 |
| 42 |
12852704 | Valdecoxib: a review. | 2003 Mar |
1 |
| 43 |
14507922 | Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. | 2003 Dec 19 |
1 |
| 44 |
11874389 | Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use. | 2002 Mar |
1 |
| 45 |
11296547 | Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. | 2001 |
1 |
| 46 |
11433218 | A pleiotropic antiatherogenic action of ibuprofen. | 2001 Jul-Aug |
1 |
| 47 |
11742186 | Gastro-duodenal protection in an era of cyclo-oxygenase-2-selective nonsteroidal anti-inflammatory drugs. | 2001 Dec |
1 |
| 48 |
11771569 | Overview on clinical data of dexibuprofen. | 2001 Nov |
1 |
| 49 |
10877012 | Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. | 2000 May |
2 |
| 50 |
11009046 | A comparison of the effects of etodolac and ibuprofen on renal haemodynamics, tubular function, renin, vasopressin and urinary excretion of albumin and alpha-glutathione-S-transferase in healthy subjects: a placebo-controlled cross-over study. | 2000 Aug |
1 |