Kynurenic Acid

aminoadipate aminotransferase ; Homo sapiens







21 Article(s)
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1 35063739 Alterations in the kynurenine pathway and excitatory amino acid transporter-2 in depression with and without psychosis: Evidence of a potential astrocyte pathology. 2022 Mar 1
2 32153151 Kynurenine Aminotransferases I, II and III Are Present in Saliva. 2020 Mar 11 1
3 29537924 Fragment Screening of Human Kynurenine Aminotransferase-II. 2018 Jul 4
4 29689093 Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters. 2018 2
5 29242525 Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives. 2017 Dec 14 2
6 26874021 Development of a RapidFire mass spectrometry assay and a fluorescence assay for the discovery of kynurenine aminotransferase II inhibitors to treat central nervous system disorders. 2016 May 15 2
7 27023527 Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution. 2016 Mar 25 4
8 27072370 Polymorphism of Kynurenine Pathway-Related Genes, Kynurenic Acid, and Psychopathological Symptoms in HIV. 2016 Sep 2
9 27314340 Kynurenine Aminotransferase Isozyme Inhibitors: A Review. 2016 Jun 15 1
10 26454650 Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat. 2015 Dec 1
11 25231977 Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine. 2014 Nov 7 1
12 20684605 Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement. 2010 Aug 12 1
13 19226371 On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. 2009 Apr 4
14 19715778 Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: the round dance of kynurenine aminotransferase II. 2009 Dec 1
15 18056995 Crystal structure of human kynurenine aminotransferase II. 2008 Feb 8 4
16 18056996 Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia. 2008 Feb 8 1
17 18620547 Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. 2008 Aug 2
18 16511030 Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3. 2005 Mar 1 1
19 14559362 Determination of alpha-aminoadipic acid in brain, peripheral tissues, and body fluids using GC/MS with negative chemical ionization. 2003 Oct 21 1
20 10441733 Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease. 1999 Sep 1
21 8350986 Characterization of human brain kynurenine aminotransferases using [3H]kynurenine as a substrate. 1993 Jul 1