Hyaluronic Acid

hyaluronidase 1 ; Homo sapiens







37 Article(s)
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1 35543351 Cell migration inducing hyaluronidase 1 promotes growth and metastasis of papillary thyroid carcinoma. 2022 May 1
2 32363767 Hyaluronic-Acid-Presenting Self-Assembled Nanoparticles Transform a Hyaluronidase HYAL1 Substrate into an Efficient and Selective Inhibitor. 2020 Aug 3 5
3 32441104 Noncovalently Caged Firefly Luciferins Enable Amplifiable Bioluminescence Sensing of Hyaluronidase-1 Activity in Vivo. 2020 Jun 26 4
4 29673760 Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. 2019 May 1
5 30705130 Serum levels of hyaluronic acid are associated with COPD severity and predict survival. 2019 Mar 1
6 30990018 Differentiation of Intracellular Hyaluronidase Isoform by Degradable Nanoassembly Coupled with RNA-Binding Fluorescence Amplification. 2019 May 21 4
7 29063508 Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. 2018 Jan 1
8 30176279 Isoflavonoids with inhibiting effects on human hyaluronidase-1 and norneolignan clitorienolactone B from Ononis spinosa L. root extract. 2018 Oct 2
9 27419371 Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer. 2017 Apr 11 2
10 28168629 Role of HYAL1 expression in primary breast cancer in the formation of brain metastases. 2017 Apr 2
11 28604766 The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function. 2017 Jun 12 1
12 28888002 Construction of multifunctional porous silica nanocarriers for pH/enzyme-responsive drug release. 2017 Dec 1 2
13 27764788 Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells. 2016 Nov 22 1
14 24668563 Elevated hyaluronan and hyaluronan-mediated motility receptor are associated with biochemical failure in patients with intermediate-grade prostate tumors. 2014 Jun 15 1
15 24820161 C-mannosylation of human hyaluronidase 1: possible roles for secretion and enzymatic activity. 2014 Jul 4
16 25009769 N-glycosylation is required for secretion and enzymatic activity of human hyaluronidase1. 2014 2
17 23377816 Presence of hyaluronidase isoforms in nasal polyps. 2013 Jan 1
18 21887686 Molecular characterization of kidney cancer: association of hyaluronic acid family with histological subtypes and metastasis. 2012 May 1 1
19 24970149 Hyaluronidases Have Strong Hydrolytic Activity toward Chondroitin 4-Sulfate Comparable to that for Hyaluronan. 2012 Nov 12 2
20 20960509 Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis. 2011 Mar 15 1
21 21555367 Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells. 2011 Jun 15 2
22 21743962 Fragmented hyaluronan is an autocrine chemokinetic motility factor supported by the HAS2-HYAL2/CD44 system on the plasma membrane. 2011 Nov 2
23 19889881 Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic linkage in the trisulfated tetrasaccharide sequence. 2010 Mar 3
24 20558613 Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration. 2010 Sep 23 2
25 20875124 Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma. 2010 Sep 27 3
26 19218337 Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing. 2009 Mar 1
27 19408825 Plasma hyaluronidase activity as an indicator of atherosclerosis in patients with coronary artery disease. 2009 1
28 19435493 Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content. 2009 May 12 2
29 19478093 Designed human serum hyaluronidase 1 variant, HYAL1DeltaL, exhibits activity up to pH 5.9. 2009 Jul 17 1
30 18718911 Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter. 2008 Oct 24 2
31 18768572 Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. 2008 Dec 2
32 17170110 CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2. 2007 Feb 23 1
33 17503783 Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis. 2007 Jun 12 1
34 17145867 HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 Dec 1 1
35 15781637 HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion. 2005 Mar 15 1
36 16104017 Structures of vertebrate hyaluronidases and their unique enzymatic mechanism of hydrolysis. 2005 Nov 1 1
37 11731267 The six hyaluronidase-like genes in the human and mouse genomes. 2001 Dec 2