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34709101 | Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. | 2022 Apr |
1 |
| 2 |
34785186 | Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning: A scoping review. | 2022 Feb 1 |
1 |
| 3 |
34978586 | Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. | 2022 Feb |
1 |
| 4 |
32762579 | Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review. | 2020 Dec |
3 |
| 5 |
33157119 | 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. | 2020 Dec 15 |
4 |
| 6 |
28300663 | 1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism. | 2017 Apr 15 |
2 |
| 7 |
24287576 | Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1. | 2014 Mar |
1 |
| 8 |
23352969 | Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure. | 2013 Mar 14 |
2 |
| 9 |
23707663 | Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells. | 2013 Oct |
1 |
| 10 |
22807108 | CYP2E1 metabolism of styrene involves allostery. | 2012 Oct |
1 |
| 11 |
18473182 | Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR). | 2009 Jun |
1 |
| 12 |
19004845 | Fomepizole: a critical assessment of current dosing recommendations. | 2009 Feb |
1 |
| 13 |
18056994 | CYP2E1 substrate inhibition. Mechanistic interpretation through an effector site for monocyclic compounds. | 2008 Feb 8 |
1 |
| 14 |
18818195 | Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. | 2008 Nov 28 |
1 |
| 15 |
16337880 | Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1. | 2006 Jan 1 |
1 |
| 16 |
16814747 | Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity. | 2006 Aug 28 |
1 |
| 17 |
14695664 | Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. | 2004 Feb |
1 |
| 18 |
15242817 | Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1. | 2004 Aug 1 |
1 |
| 19 |
12584152 | Metabolism of chloroform in the human liver and identification of the competent P450s. | 2003 Mar |
2 |
| 20 |
12386121 | Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites. | 2002 Nov |
1 |
| 21 |
12420748 | Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging ability of isoniazid. | 2002 Aug |
1 |
| 22 |
11397396 | The metabolism of beta-chloroprene: preliminary in-vitro studies using liver microsomes. | 2001 Jun 1 |
1 |
| 23 |
10029205 | Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1. | 1999 Jan |
2 |
| 24 |
10510285 | NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species. | 1999 Oct 15 |
2 |
| 25 |
9884161 | Respective roles of human cytochrome P-4502E1, 1A2, and 3A4 in the hepatic microsomal ethanol oxidizing system. | 1998 Dec |
1 |
| 26 |
9143349 | Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. | 1997 May 1 |
2 |
| 27 |
9438519 | Cytochrome P-4502E1-dependent formation of trifluoroacetyl adducts from halothane by transduced HepG2 cells. | 1997 Dec |
1 |
| 28 |
8831679 | Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells. | 1996 Sep 24 |
2 |
| 29 |
8971135 | Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations. | 1996 Dec |
1 |
| 30 |
7589226 | Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells. | 1995 Jul 1 |
1 |
| 31 |
8531136 | Inactivation and degradation of human cytochrome P4502E1 by CCl4 in a transfected HepG2 cell line. | 1995 Dec |
1 |
| 32 |
1627587 | Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole. | 1992 Jul 21 |
1 |