| 1 |
23256458 | The role of human cytochrome P450 enzymes in metabolism of acrylamide in vitro. | 2013 Jun |
3 |
| 2 |
23577625 | The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism. | 2013 Jun 5 |
6 |
| 3 |
18950609 | Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1. | 2009 Apr 15 |
1 |
| 4 |
18418580 | Human CYP2E1 mediates the formation of glycidamide from acrylamide. | 2008 Oct |
2 |
| 5 |
17697034 | Is bupropion a more specific substrate for porcine CYP2E than chlorzoxazone and p-nitrophenol? | 2007 Sep |
1 |
| 6 |
15778271 | Minipig cytochrome P450 2E1: comparison with human enzyme. | 2005 Jun |
1 |
| 7 |
15878691 | Acetaminophen decreases intracellular glutathione levels and modulates cytokine production in human alveolar macrophages and type II pneumocytes in vitro. | 2005 Aug |
1 |
| 8 |
15997102 | Inhibition of human cytochrome P450 2E1 by halogenated anilines, phenols, and thiophenols. | 2005 Jul |
2 |
| 9 |
15122651 | Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1. | 2004 |
2 |
| 10 |
12803597 | Concordance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats. | 2003 Jul |
1 |
| 11 |
10803680 | Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes. | 2000 Apr |
1 |
| 12 |
10821163 | Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450. | 2000 Apr |
1 |
| 13 |
11501186 | In vitro proguanil activation to cycloguanil is mediated by CYP2C19 and CYP3A4 in adult Chinese liver microsomes. | 2000 Aug |
1 |
| 14 |
10207612 | Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression. | 1999 Feb |
1 |
| 15 |
10215755 | Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism. | 1999 Mar |
1 |
| 16 |
10348802 | Lack of single-dose disulfiram effects on cytochrome P-450 2C9, 2C19, 2D6, and 3A4 activities: evidence for specificity toward P-450 2E1. | 1999 Jun |
2 |
| 17 |
10418968 | Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential. | 1999 Jun 1 |
1 |
| 18 |
10421611 | Involvement of CYP2E1 as A low-affinity enzyme in phenacetin O-deethylation in human liver microsomes. | 1999 Aug |
1 |
| 19 |
10471070 | Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans. | 1999 Jun |
2 |
| 20 |
9695717 | Single-dose disulfiram does not inhibit CYP2A6 activity. | 1998 Jul |
2 |
| 21 |
9705891 | Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts. | 1998 Jul |
2 |
| 22 |
9113344 | Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species. | 1997 Apr |
2 |
| 23 |
9113345 | Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1. | 1997 Apr |
2 |
| 24 |
9394024 | Cytochrome P450 isozymes involved in lisofylline metabolism to pentoxifylline in human liver microsomes. | 1997 Dec |
1 |
| 25 |
8558417 | Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene. | 1996 Jan |
1 |
| 26 |
8819299 | Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. | 1996 Jul |
2 |
| 27 |
8870687 | Inter-individual variability in the oxidation of 1,2-dibromoethane: use of heterologously expressed human cytochrome P450 and human liver microsomes. | 1996 Sep 6 |
2 |
| 28 |
7550365 | Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1. | 1995 Jun |
1 |
| 29 |
7720520 | Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes. | 1995 Jan |
1 |
| 30 |
8203907 | Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450. | 1994 Jun |
4 |
| 31 |
8204093 | Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms. | 1994 May 18 |
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| 32 |
8267647 | Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques. | 1993 Dec 3 |
2 |
| 33 |
8513656 | Single-dose disulfiram inhibition of chlorzoxazone metabolism: a clinical probe for P450 2E1. | 1993 Jun |
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