| 1 |
34938609 | Allele-specific targeting of mutant ataxin-3 by antisense oligonucleotides in SCA3-iPSC-derived neurons. | 2022 Mar 8 |
3 |
| 2 |
35386195 | Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model. | 2022 |
2 |
| 3 |
35488942 | Altered glucose metabolism and its association with carbonic anhydrase 8 in Machado-Joseph Disease. | 2022 Apr 30 |
2 |
| 4 |
35587620 | Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood. | 2022 May |
1 |
| 5 |
35587632 | Reply to: "Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood". | 2022 May |
1 |
| 6 |
33065068 | Capturing the Conformational Ensemble of the Mixed Folded Polyglutamine Protein Ataxin-3. | 2021 Jan 7 |
1 |
| 7 |
33106888 | PolyQ-expanded ataxin-3 protein levels in peripheral blood mononuclear cells correlate with clinical parameters in SCA3: a pilot study. | 2021 Apr |
5 |
| 8 |
33542212 | A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3. | 2021 Feb 2 |
5 |
| 9 |
33629274 | Mutant Ataxin-3-Containing Aggregates (MATAGGs) in Spinocerebellar Ataxia Type 3: Dynamics of the Disorder. | 2021 Jul |
3 |
| 10 |
33741019 | Neurodegenerative phosphoprotein signaling landscape in models of SCA3. | 2021 Mar 19 |
2 |
| 11 |
33837238 | PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates. | 2021 Apr 9 |
1 |
| 12 |
34199295 | n-Butylidenephthalide Modulates Autophagy to Ameliorate Neuropathological Progress of Spinocerebellar Ataxia Type 3 through mTOR Pathway. | 2021 Jun 13 |
6 |
| 13 |
34303201 | Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3. | 2021 Aug |
13 |
| 14 |
34345727 | Clinical and genetic profile in index patients with spinocerebellar ataxia type 3 in Indonesia: case report. | 2021 Jul |
1 |
| 15 |
34397117 | Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood. | 2021 Nov |
4 |
| 16 |
34416891 | Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo. | 2021 Aug 20 |
1 |
| 17 |
34535635 | CRISPR/Cas9 mediated gene correction ameliorates abnormal phenotypes in spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cells. | 2021 Sep 17 |
2 |
| 18 |
34685571 | A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3. | 2021 Sep 29 |
6 |
| 19 |
35111747 | MicroRNA-409-3p Targeting at ATXN3 Reduces the Apoptosis of Dopamine Neurons Based on the Profile of miRNAs in the Cerebrospinal Fluid of Early Parkinson's Disease. | 2021 |
1 |
| 20 |
31625269 | The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy. | 2020 Jan |
2 |
| 21 |
31669734 | Pathogenesis of SCA3 and implications for other polyglutamine diseases. | 2020 Feb |
1 |
| 22 |
31767406 | Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteins. | 2020 Jan 1 |
1 |
| 23 |
31783119 | Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein. | 2020 Apr |
5 |
| 24 |
31927329 | Universal RNAi Triggers for the Specific Inhibition of Mutant Huntingtin, Atrophin-1, Ataxin-3, and Ataxin-7 Expression. | 2020 Mar 6 |
2 |
| 25 |
31970864 | The Machado-Joseph disease-associated form of ataxin-3 impacts dynamics of clathrin-coated pits. | 2020 May |
4 |
| 26 |
32274760 | Machado-Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides. | 2020 |
6 |
| 27 |
32361312 | Generation of human iPS cell line IBCHi002-A from spinocerebellar ataxia type 3/Machado-Joseph disease patient's fibroblasts. | 2020 May |
3 |
| 28 |
32643791 | Degron capability of the hydrophobic C-terminus of the polyglutamine disease protein, ataxin-3. | 2020 Oct |
2 |
| 29 |
33087504 | Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. | 2020 Oct 21 |
10 |
| 30 |
33425926 | Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond. | 2020 |
4 |
| 31 |
30147021 | Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients. | 2019 |
7 |
| 32 |
30455355 | Physiological and pathophysiological characteristics of ataxin-3 isoforms. | 2019 Jan 11 |
2 |
| 33 |
30707359 | EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases. | 2019 Mar |
2 |
| 34 |
31188927 | State biomarkers for Machado Joseph disease: Validation, feasibility and responsiveness to change. | 2019 |
2 |
| 35 |
31310802 | Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3. | 2019 Dec |
2 |
| 36 |
31374463 | Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line. | 2019 Aug |
1 |
| 37 |
31378764 | Disulfiram facilitates ataxin-3 nuclear translocation and potentiates the cytotoxicity in a cell model of SCA3. | 2019 |
2 |
| 38 |
31683630 | Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing. | 2019 Oct 31 |
6 |
| 39 |
31687087 | Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons. | 2019 |
2 |
| 40 |
31691128 | From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation. | 2019 Oct |
3 |
| 41 |
31828177 | Development of an AAV-Based MicroRNA Gene Therapy to Treat Machado-Joseph Disease. | 2019 Dec 13 |
1 |
| 42 |
29111377 | Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function. | 2018 Jan |
8 |
| 43 |
29229556 | Experimental and Clinical Strategies for Treating Spinocerebellar Ataxia Type 3. | 2018 Feb 10 |
3 |
| 44 |
29334808 | Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. | 2018 Feb |
6 |
| 45 |
29427106 | The Neuropathology of Spinocerebellar Ataxia Type 3/Machado-Joseph Disease. | 2018 |
2 |
| 46 |
29427109 | Polyglutamine-Independent Features in Ataxin-3 Aggregation and Pathogenesis of Machado-Joseph Disease. | 2018 |
1 |
| 47 |
29661116 | CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells. | 2018 Jun 1 |
9 |
| 48 |
29972812 | The Structural Properties in Solution of the Intrinsically Mixed Folded Protein Ataxin-3. | 2018 Jul 3 |
1 |
| 49 |
30036587 | The Machado-Joseph disease-associated expanded form of ataxin-3: Overexpression, purification, and preliminary biophysical and structural characterization. | 2018 Dec |
2 |
| 50 |
30042316 | Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol. | 2018 Jul 24 |
1 |