Mephenytoin

cytochrome P450 family 1 subfamily A member 2 ; Homo sapiens







7 Article(s)
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1 33302490 A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug-Drug-Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine. 2020 Dec 8 1
2 29403890 An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes. 2014 Aug 1
3 17542019 In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography. 2007 Sep 1
4 16049126 Automated assessment of time-dependent inhibition of human cytochrome P450 enzymes using liquid chromatography-tandem mass spectrometry analysis. 2005 Nov 1
5 12900870 Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone. 2003 Aug 1
6 11851639 Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects. 2002 Feb 1
7 15618695 Application of microtiter plate assay to evaluate inhibitory effects of various compounds on nine cytochrome P450 isoforms and to estimate their inhibition patterns. 2002 1