Olanzapine

cytochrome P450 family 1 subfamily A member 2 ; Homo sapiens







44 Article(s)
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1 34335273 Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone. 2021 3
2 34442334 Functional Characterization of 21 Rare Allelic CYP1A2 Variants Identified in a Population of 4773 Japanese Individuals by Assessing Phenacetin O-Deethylation. 2021 Jul 22 2
3 34528455 The pharmacogenetics of treatment with olanzapine. 2021 Sep 1
4 32070304 The association of genetic polymorphisms in CYP1A2, UGT1A4, and ABCB1 with autonomic nervous system dysfunction in schizophrenia patients treated with olanzapine. 2020 Feb 18 1
5 32250470 The effects of aripiprazole and olanzapine on pupillary light reflex and its relationship with pharmacogenetics in a randomized multiple-dose trial. 2020 Oct 1
6 32992097 Association of the genetic polymorphisms of metabolizing enzymes, transporters, target receptors and their interactions with treatment response to olanzapine in chinese han schizophrenia patients. 2020 Nov 1
7 30888624 A Phase I Open-Label Study to Evaluate the Effects of Rifampin on the Pharmacokinetics of Olanzapine and Samidorphan Administered in Combination in Healthy Human Subjects. 2019 May 1
8 26856397 Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3. 2016 Mar 3
9 25090458 CYP1A2*1D and *1F polymorphisms have a significant impact on olanzapine serum concentrations. 2015 Apr 4
10 24929949 Effect of fosamprenavir/ritonavir on the pharmacokinetics of single-dose olanzapine in healthy volunteers. 2014 Aug 1
11 23492908 Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure. 2013 May 5
12 23641727 Considering CYP1A2 phenotype and genotype for optimizing the dose of olanzapine in the management of schizophrenia. 2013 Sep 3
13 23930678 Pharmacogenetics of olanzapine metabolism. 2013 Aug 2
14 22554278 Measurement of CYP1A2 activity: a focus on caffeine as a probe. 2012 Jun 1 1
15 21395655 The effect of ethinylestradiol-containing contraceptives on the serum concentration of olanzapine and N-desmethyl olanzapine. 2011 Apr 1
16 19636338 Pharmacogenetics and olanzapine treatment: CYP1A2*1F and serotonergic polymorphisms influence therapeutic outcome. 2010 Feb 4
17 20143052 Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients. 2010 May 1
18 19490292 A review of smoking cessation: potentially risky effects on prescribed medications. 2009 Jun 1
19 19794359 Smoking and schizophrenia. 2009 Sep 1
20 18537577 Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions. 2008 Jun 1
21 16969362 Genetic susceptibility to Tardive Dyskinesia in chronic schizophrenia subjects: V. Association of CYP1A2 1545 C>T polymorphism. 2007 Oct 1
22 17214606 Metabolic drug interactions with newer antipsychotics: a comparative review. 2007 Jan 1
23 17823102 Drug interactions with smoking. 2007 Sep 15 1
24 16805946 Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents. 2006 Jul 2
25 17089108 The effect of variable cigarette consumption on the interaction with clozapine and olanzapine. 2006 Dec 2
26 15738749 Low-dose fluvoxamine as an adjunct to reduce olanzapine therapeutic dose requirements: a prospective dose-adjusted drug interaction strategy. 2005 Apr 3
27 15883149 The dosing of atypical antipsychotics. 2005 May-Jun 2
28 15323601 Variables associated with high olanzapine dosing in a state hospital. 2004 Aug 2
29 15545309 Dose-dependent alternations in the pharmacokinetics of olanzapine during coadministration of fluvoxamine in patients with schizophrenia. 2004 Dec 4
30 26984311 Olanzapine metabolism by CYP1A2/CYP2D6 and hyperglycaemia. 2004 Aug 2
31 12640212 Role of the smoking-induced cytochrome P450 (CYP)1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine. 2003 Apr 5
32 12644842 Correlation of cytochrome P450 (CYP) 1A2 activity using caffeine phenotyping and olanzapine disposition in healthy volunteers. 2003 May 3
33 12665390 Fatalities associated with therapeutic use and overdose of atypical antipsychotics. 2003 2
34 12670127 Interactions between the cytochrome P450 system and the second-generation antipsychotics. 2003 Mar 1
35 11981356 Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapine. 2002 May 2
36 12172335 Influence of ritonavir on olanzapine pharmacokinetics in healthy volunteers. 2002 Aug 1
37 12186270 New antipsychotic agents for schizophrenia: pharmacokinetics and metabolism update. 2002 Jul 1
38 12352274 Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects. 2002 Oct 1
39 11477325 Fluvoxamine but not sertraline inhibits the metabolism of olanzapine: evidence from a therapeutic drug monitoring service. 2001 Aug 1
40 11699614 Olanzapine disposition in humans is unrelated to CYP1A2 and CYP2D6 phenotypes. 2001 Sep 1
41 10422890 Drug metabolism and atypical antipsychotics. 1999 Jun 1
42 10511917 Olanzapine. Pharmacokinetic and pharmacodynamic profile. 1999 Sep 1
43 9855322 Lack of effect of olanzapine on the pharmacokinetics of a single aminophylline dose in healthy men. 1998 Nov-Dec 1
44 9860152 A pharmacokinetic interaction between carbamazepine and olanzapine: observations on possible mechanism. 1998 Oct 4