| 1 |
28879062 | A modeling approach to evaluate the balance between bioactivation and detoxification of MeIQx in human hepatocytes. | 2017 |
2 |
| 2 |
20004212 | Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx). | 2010 Feb 3 |
2 |
| 3 |
20307560 | Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells. | 2010 Jun 1 |
1 |
| 4 |
12351158 | Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2. | 2002 Sep 30 |
1 |
| 5 |
11258970 | Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2. | 2001 Feb |
1 |
| 6 |
11453738 | Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2. | 2001 Jul |
1 |
| 7 |
10537291 | N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: excretion of the N2-glucuronide conjugate of 2-hydroxyamino-MeIQx in urine. | 1999 Oct 15 |
4 |
| 8 |
9202738 | Assessing human risk to heterocyclic amines. | 1997 May 12 |
1 |
| 9 |
9270013 | Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity. | 1997 Aug 15 |
3 |
| 10 |
8678801 | Chemical methods for assessing systemic exposure to dietary heterocyclic amines in man. | 1996 |
1 |
| 11 |
7586210 | Lower levels of urinary 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) in humans with higher CYP1A2 activity. | 1995 Nov |
6 |
| 12 |
8844810 | Systemic exposure to dietary heterocyclic amines in man. | 1995 |
1 |
| 13 |
8012961 | Stable expression of human CYP1A2 and N-acetyltransferases in Chinese hamster CHL cells: mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. | 1994 Jul 1 |
2 |
| 14 |
8261468 | CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. | 1994 Jan 1 |
1 |
| 15 |
8472319 | Human hepatic CYP1A1 and CYP1A2 content, determined with specific anti-peptide antibodies, correlates with the mutagenic activation of PhIP. | 1993 Apr |
2 |
| 16 |
1473228 | N-hydroxy-MeIQx is the major microsomal oxidation product of the dietary carcinogen MeIQx with human liver. | 1992 Dec |
2 |