Diclofenac

cytochrome P450 family 1 subfamily A member 2 ; Homo sapiens







10 Article(s)
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Pub. Year
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1 29027194 Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children. 2018 Jul 1
2 25936586 In vitro inhibition of human cytochrome P450 by cudratricusxanthone A. 2015 Jul 1
3 23777257 Drug interactions of diclofenac and its oxidative metabolite with human liver microsomal cytochrome P450 1A2-dependent drug oxidation. 2014 Jan 2
4 24695277 Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism. 2014 1
5 23153057 Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy. 2013 Apr 1
6 20877236 Effects of eupatilin and jaceosidin on cytochrome p450 enzyme activities in human liver microsomes. 2010 Sep 16 1
7 17542019 In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography. 2007 Sep 1
8 16049126 Automated assessment of time-dependent inhibition of human cytochrome P450 enzymes using liquid chromatography-tandem mass spectrometry analysis. 2005 Nov 1
9 12781337 Preclinical factors affecting the interindividual variability in the clearance of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. 2003 Jun 1 1
10 15618695 Application of microtiter plate assay to evaluate inhibitory effects of various compounds on nine cytochrome P450 isoforms and to estimate their inhibition patterns. 2002 1