| 1 |
32060993 | Inhibition of human CYP1 enzymes by a classical inhibitor α-naphthoflavone and a novel inhibitor N-(3, 5-dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study. | 2020 May |
1 |
| 2 |
30865484 | Cytotoxicity of safrole in HepaRG cells: studies on the role of CYP1A2-mediated ortho-quinone metabolic activation. | 2019 Dec |
3 |
| 3 |
28475969 | Investigation of substrate recognition for cytochrome P450 1A2 mediated by water molecules using docking and molecular dynamics simulations. | 2017 Jun |
1 |
| 4 |
26126958 | Metabolism of (-)-cis- and (-)-trans-rose oxide by cytochrome P450 enzymes in human liver microsomes. | 2015 Dec |
1 |
| 5 |
26614990 | In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes. | 2015 Nov |
1 |
| 6 |
20388857 | Differential roles of phase I and phase II enzymes in 3,4-methylendioxymethamphetamine-induced cytotoxicity. | 2010 Jul |
1 |
| 7 |
20435083 | Cytochromes P4501 (CYP1): catalytic activities and inducibility by diesel exhaust particle extract and benzo[a]pyrene in intact human lung ex vivo. | 2010 Jun 29 |
1 |
| 8 |
20806393 | Differential mechanisms for the inhibition of human cytochrome P450 1A2 by apigenin and genistein. | 2010 Jul-Aug |
1 |
| 9 |
19702529 | Insights into the structure, function, and regulation of human cytochrome P450 1A2. | 2009 Sep |
1 |
| 10 |
19754423 | Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. | 2009 |
1 |
| 11 |
17962373 | Identification of cytochrome P450 enzymes involved in the metabolism of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone. | 2008 Jan |
1 |
| 12 |
18322074 | Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z)-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68). | 2008 Jun |
1 |
| 13 |
17620218 | Involvement of human cytochrome P450 2B6 in the omega- and 4-hydroxylation of the anesthetic agent propofol. | 2007 Jul |
1 |
| 14 |
16631089 | Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine. | 2006 Apr |
1 |
| 15 |
15766918 | Molecular cloning and functional analysis of cytochrome P450 1A2 from Japanese monkey liver: comparison with marmoset cytochrome P450 1A2. | 2005 Feb 28 |
1 |
| 16 |
15056479 | The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes. | 2004 May |
1 |
| 17 |
15276085 | Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes. | 2004 Aug 15 |
1 |
| 18 |
12758162 | Tight-binding inhibition by alpha-naphthoflavone of human cytochrome P450 1A2. | 2003 May 30 |
1 |
| 19 |
11744615 | CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation. | 2002 Jan |
1 |
| 20 |
11782366 | Comparative aflatoxin B(1) activation and cytotoxicity in human bronchial cells expressing cytochromes P450 1A2 and 3A4. | 2002 Jan 1 |
1 |
| 21 |
12147246 | Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone. | 2002 Aug 9 |
1 |
| 22 |
11231111 | High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. V. Validation of a direct injection/on-line guard cartridge extraction--tandem mass spectrometry method for CYP1A2 inhibition assessment. | 2001 Feb |
1 |
| 23 |
11295446 | Influence of ligand binding to human cytochrome P-450 1A2: conformational activation and stabilization by alpha-naphthoflavone. | 2001 Apr 7 |
1 |
| 24 |
10901285 | Identification of human cytochrome P450 isoforms involved in the 7-hydroxylation of chlorpromazine by human liver microsomes. | 2000 |
1 |
| 25 |
11315102 | Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1. | 2000 Oct |
1 |
| 26 |
10473105 | Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1. | 1999 Aug |
2 |
| 27 |
9435160 | Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. | 1998 Jan |
1 |
| 28 |
9549641 | Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4. | 1998 Feb |
1 |
| 29 |
9643585 | Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens. | 1998 May |
1 |
| 30 |
9763414 | Human biotransformation of bropirimine. Characterization of the major bropirimine oxidative metabolites formed in vitro. | 1998 Oct |
1 |
| 31 |
9105404 | Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole. | 1997 Feb 21 |
1 |
| 32 |
9316860 | Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro. | 1997 Sep |
1 |
| 33 |
9351903 | Formation of guanoxabenz from guanabenz in human liver. A new metabolic marker for CYP1A2. | 1997 Nov |
2 |
| 34 |
8786569 | Theophylline metabolism in human liver microsomes: inhibition studies. | 1996 Mar |
1 |
| 35 |
7833826 | Modulation of cytochrome P450 activities by 7,8-benzoflavone and its metabolites. | 1994 Oct |
1 |
| 36 |
7895609 | Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase. | 1994 Nov-Dec |
1 |
| 37 |
8155716 | Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids. | 1994 Apr 13 |
1 |
| 38 |
8474022 | Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2. | 1993 Apr |
2 |
| 39 |
1306118 | Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. | 1992 Aug |
1 |
| 40 |
3413034 | Inhibitor panel studies of human hepatic and placental cytochrome P-450-associated monooxygenase activities. | 1988 May |
1 |
| 41 |
3984427 | [Metabolism of foreign substances in human skin and hair follicles]. | 1985 Jan |
2 |
| 42 |
4077222 | Presence of cytochrome P-450-dependent monooxygenase in intimal cells of the hog aorta. | 1985 Nov-Dec |
1 |