| 51 |
18834363 | The effect of transcatheter arterial chemoembolization on CYP1A2 activity in patients with hepatocellular carcinoma. | 2008 Oct |
1 |
| 52 |
17542019 | In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography. | 2007 Sep |
1 |
| 53 |
17618427 | Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation. | 2007 Sep |
1 |
| 54 |
16857327 | Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028. | 2006 Oct 10 |
1 |
| 55 |
23045133 | Measurement of human cytochrome P4501A2 (CYP1A2) activity in vitro. | 2006 |
2 |
| 56 |
15766918 | Molecular cloning and functional analysis of cytochrome P450 1A2 from Japanese monkey liver: comparison with marmoset cytochrome P450 1A2. | 2005 Feb 28 |
2 |
| 57 |
16049126 | Automated assessment of time-dependent inhibition of human cytochrome P450 enzymes using liquid chromatography-tandem mass spectrometry analysis. | 2005 Nov |
1 |
| 58 |
15043991 | Inhibition of cytochrome P450 activities by oleanolic acid and ursolic acid in human liver microsomes. | 2004 Apr 16 |
1 |
| 59 |
15231049 | Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats. | 2004 Jun |
1 |
| 60 |
15742976 | Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison. | 2004 Sep |
1 |
| 61 |
15801540 | Use of a cocktail of probe substrates for drug-metabolizing enzymes for the assessment of the metabolic capacity of hepatocyte preparations. | 2004 Nov-Dec |
1 |
| 62 |
12814974 | Cytochrome P450 inhibition using recombinant proteins and mass spectrometry/multiple reaction monitoring technology in a cassette incubation. | 2003 Jul |
1 |
| 63 |
11948533 | Evaluation of approach to predict the contribution of multiple cytochrome P450s in drug metabolism using relative activity factor: effects of the differences in expression levels of NADPH-cytochrome P450 reductase and cytochrome b(5) in the expression system and the differences in the marker activities. | 2002 Apr |
1 |
| 64 |
15618695 | Application of microtiter plate assay to evaluate inhibitory effects of various compounds on nine cytochrome P450 isoforms and to estimate their inhibition patterns. | 2002 |
1 |
| 65 |
11599655 | Detailed characterization of experimentally derived human hepatic CYP1A1 activity and expression using differential inhibition of ethoxyresorufin O-deethylation by fluvoxamine. | 2001 Aug |
1 |
| 66 |
11765139 | Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine. | 2001 Nov |
1 |
| 67 |
10985777 | Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants. | 2000 Sep 19 |
1 |
| 68 |
11303964 | A population approach to enzyme characterization and identification: application to phenacetin O-deethylation. | 2000 Dec |
1 |
| 69 |
10421611 | Involvement of CYP2E1 as A low-affinity enzyme in phenacetin O-deethylation in human liver microsomes. | 1999 Aug |
1 |
| 70 |
10460810 | Effect of antipsychotic drugs on human liver cytochrome P-450 (CYP) isoforms in vitro: preferential inhibition of CYP2D6. | 1999 Sep |
1 |
| 71 |
9491822 | Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes. | 1998 Feb |
1 |
| 72 |
9578183 | Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2. | 1998 Apr |
3 |
| 73 |
9712458 | Effect of active and passive cigarette smoking on CYP1A2-mediated phenacetin disposition in Chinese subjects. | 1998 Aug |
2 |
| 74 |
9825829 | Inhibitory monoclonal antibodies to human cytochrome P450 1A2: analysis of phenacetin O-deethylation in human liver. | 1998 Oct |
1 |
| 75 |
10189256 | Human cytochromes P450 mediating phenacetin O-deethylation in vitro: validation of the high affinity component as an index of CYP1A2 activity. | 1998 Dec |
2 |
| 76 |
9351907 | Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2. | 1997 Nov |
2 |
| 77 |
8885124 | The influence of ethnic factors and gender on CYP1A2-mediated drug disposition: a comparative study in Caucasian and Chinese subjects using phenacetin as a marker substrate. | 1996 Oct |
2 |
| 78 |
8986010 | Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine. | 1996 Dec |
1 |
| 79 |
7617560 | Kinetics and inhibition by fluvoxamine of phenacetin O-deethylation in V79 cells expressing human CYP1A2. | 1995 Apr |
2 |
| 80 |
7720520 | Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes. | 1995 Jan |
1 |
| 81 |
8261468 | CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. | 1994 Jan 1 |
1 |
| 82 |
8095225 | Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae. | 1993 Jan-Feb |
1 |
| 83 |
8466541 | Fluvoxamine is a potent inhibitor of cytochrome P4501A2. | 1993 Mar 24 |
2 |
| 84 |
8474022 | Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2. | 1993 Apr |
6 |
| 85 |
1306118 | Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. | 1992 Aug |
1 |