| 1 |
33386627 | Selective inhibitory effects of HYIpro-3-1 on CYP1A2 in human liver microsomes. | 2021 Jan |
1 |
| 2 |
33397254 | Metabolism and Mechanism of Human Cytochrome P450 Enzyme 1A2. | 2021 |
1 |
| 3 |
34442334 | Functional Characterization of 21 Rare Allelic CYP1A2 Variants Identified in a Population of 4773 Japanese Individuals by Assessing Phenacetin O-Deethylation. | 2021 Jul 22 |
2 |
| 4 |
31706005 | HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells. | 2020 Feb 1 |
1 |
| 5 |
32941854 | Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy. | 2020 Nov 1 |
1 |
| 6 |
31239454 | Characterization of Porcine Hepatic and Intestinal Drug Metabolizing CYP450: Comparison with Human Orthologues from A Quantitative, Activity and Selectivity Perspective. | 2019 Jun 25 |
1 |
| 7 |
31480528 | The Effect of Flavonoid Aglycones on the CYP1A2, CYP2A6, CYP2C8 and CYP2D6 Enzymes Activity. | 2019 Sep 1 |
1 |
| 8 |
28992765 | Phenotyping of CYP 4501A2 Activity by Total Overnight Salivary Caffeine Assessment (TOSCA) in Patients on Warfarin Treatment: A Cross-Sectional Study. | 2018 Sep |
1 |
| 9 |
29799514 | Increased Phenacetin Oxidation upon the L382V Substitution in Cytochrome P450 1A2 is Associated with Altered Substrate Binding Orientation. | 2018 May 25 |
4 |
| 10 |
29989011 | Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes. | 2018 Jul |
1 |
| 11 |
27794450 | 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism. | 2017 Feb |
1 |
| 12 |
28468305 | Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes. | 2017 May 1 |
1 |
| 13 |
28962866 | In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1A2. | 2017 Dec 1 |
1 |
| 14 |
26750984 | Investigation of selective inhibitory effects of glycyrol on human CYP 1A1 and 2C9. | 2016 Oct |
1 |
| 15 |
26838175 | Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli. | 2016 Feb 2 |
2 |
| 16 |
27037683 | Long-term human primary hepatocyte cultures in a microfluidic liver biochip show maintenance of mRNA levels and higher drug metabolism compared with Petri cultures. | 2016 Jul |
1 |
| 17 |
27128896 | Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. | 2016 Apr 27 |
1 |
| 18 |
27318879 | Prediction of inter-individual variability on the pharmacokinetics of CYP1A2 substrates in non-smoking healthy volunteers. | 2016 Aug |
1 |
| 19 |
25640685 | Inhibitory Mechanisms of Human CYPs by Three Alkaloids Isolated from Traditional Chinese Herbs. | 2015 Jun |
1 |
| 20 |
25936586 | In vitro inhibition of human cytochrome P450 by cudratricusxanthone A. | 2015 Jul |
1 |
| 21 |
26055126 | Selective inhibitory effects of machilin A isolated from Machilus thunbergii on human cytochrome P450 1A and 2B6. | 2015 Jun 1 |
1 |
| 22 |
26490449 | Inhibitory Activities of Thai Medicinal Plants with Promising Activities Against Malaria and Cholangiocarcinoma on Human Cytochrome P450. | 2015 Dec |
1 |
| 23 |
26614990 | In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes. | 2015 Nov |
2 |
| 24 |
24119207 | Possibility of decrease in CYP1A2 function in patients with end-stage renal disease. | 2014 Apr |
2 |
| 25 |
24194261 | In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2. | 2014 Aug |
1 |
| 26 |
25456436 | In vitro studies of berberine metabolism and its effect of enzyme induction on HepG2 cells. | 2014 Dec 2 |
3 |
| 27 |
29403890 | An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes. | 2014 Aug |
1 |
| 28 |
23000442 | Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes. | 2013 Jan |
1 |
| 29 |
23153057 | Assessment of cytochrome P450 (1A2, 2B6, 2C9 and 3A4) induction in cryopreserved human hepatocytes cultured in 48-well plates using the cocktail strategy. | 2013 Apr |
1 |
| 30 |
22305191 | Polysaccharide peptides from Coriolus versicolor competitively inhibit model cytochrome P450 enzyme probe substrates metabolism in human liver microsomes. | 2012 Mar 15 |
1 |
| 31 |
22940574 | Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia. | 2012 Nov 1 |
2 |
| 32 |
22949628 | Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism. | 2012 Dec |
4 |
| 33 |
23263815 | In vitro inhibitory effect of luotonin A on human CYP1A. | 2012 Dec |
2 |
| 34 |
23331088 | Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins. | 2012 Sep 1 |
1 |
| 35 |
21222608 | Inhibitory effects of caffeic acid ester analogues on free radicals and human liver microsome CYP1A2 activities. | 2011 Mar |
2 |
| 36 |
21825116 | Effect of dimethyl sulfoxide on in vitro cytochrome P4501A2 mediated phenacetin O-deethylation in human liver microsomes. | 2011 Nov |
3 |
| 37 |
19906068 | Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection. | 2010 Feb |
2 |
| 38 |
20335269 | Significant increase in phenacetin oxidation on L382V substitution in human cytochrome P450 1A2. | 2010 Jul |
1 |
| 39 |
20501911 | Metabolite formation kinetics and intrinsic clearance of phenacetin, tolbutamide, alprazolam, and midazolam in adenoviral cytochrome P450-transfected HepG2 cells and comparison with hepatocytes and in vivo. | 2010 Sep |
1 |
| 40 |
20528625 | Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae. | 2010 Aug |
1 |
| 41 |
20609070 | In-vitro and in-vivo evaluations of cytochrome P450 1A2 interactions with nuciferine. | 2010 May |
1 |
| 42 |
20877236 | Effects of eupatilin and jaceosidin on cytochrome p450 enzyme activities in human liver microsomes. | 2010 Sep 16 |
1 |
| 43 |
21086794 | Development of a high throughput single nucleotide polymorphism screening method for the cytochrome P450 1A2 polymorphisms CYP1A2*1C and CYP1A2*1F: are they useful as predictive markers in mental disorders? | 2010 |
2 |
| 44 |
21091898 | Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites. | 2010 Dec |
2 |
| 45 |
19204080 | A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes. | 2009 May |
1 |
| 46 |
19904008 | Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism--an in vitro study. | 2009 Sep-Oct |
1 |
| 47 |
18197403 | Celecoxib is a CYP1A2 inhibitor in vitro but not in vivo. | 2008 May |
1 |
| 48 |
18307373 | In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. | 2008 |
1 |
| 49 |
18573860 | Characterization of substrate specificity of dog CYP1A2 using CYP1A2-deficient and wild-type dog liver microsomes. | 2008 Sep |
1 |
| 50 |
18819885 | [Effect of ketoconazole on the activity of CYP4503A4 and CYP450 1A2 of hepatic microsomes in healthy adults]. | 2008 Aug |
1 |