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30762305 | Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam. | 2019 May |
1 |
| 2 |
31569378 | The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR. | 2019 Sep 28 |
1 |
| 3 |
31676845 | Rapid maturation of the hepatic cell line Huh7 via CDK inhibition for PXR dependent CYP450 metabolism and induction. | 2019 Nov 1 |
1 |
| 4 |
29357810 | Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells. | 2018 |
2 |
| 5 |
29469947 | Evaluation of the metabolic capability of primary human hepatocytes in three-dimensional cultures on microstructural plates. | 2018 Apr |
1 |
| 6 |
30347615 | Optimized protocol for induction of cytochrome P450 enzymes 1A2 and 3A4 in human primary-like hepatocyte cell strain HepaFH3 to study in vitro toxicology. | 2018 |
1 |
| 7 |
28674261 | Preliminary Evaluation of Three-Dimensional Primary Human Hepatocyte Culture System for Assay of Drug-Metabolizing Enzyme-Inducing Potential. | 2017 |
1 |
| 8 |
26759747 | Rifampin-warfarin interaction in a mitral valve replacement patient receiving rifampin for infective endocarditis: a case report. | 2016 |
1 |
| 9 |
27917125 | Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail. | 2016 |
1 |
| 10 |
25600204 | Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays. | 2015 |
1 |
| 11 |
24316028 | The role of genetic polymorphisms in cytochrome P450 and effects of tuberculosis co-treatment on the predictive value of CYP2B6 SNPs and on efavirenz plasma levels in adult HIV patients. | 2014 Feb |
1 |
| 12 |
24553381 | Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450. | 2014 May |
1 |
| 13 |
24752503 | Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. | 2014 Jul |
1 |
| 14 |
21111054 | Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2. | 2011 May-Jun |
1 |
| 15 |
21555507 | Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture. | 2011 Aug |
1 |
| 16 |
21930825 | Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. | 2011 Dec |
1 |
| 17 |
19854261 | Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. | 2010 Mar |
1 |
| 18 |
20019244 | Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. | 2010 Mar |
1 |
| 19 |
20583967 | A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin. | 2010 Dec |
2 |
| 20 |
19686824 | Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes. | 2009 Dec 1 |
1 |
| 21 |
19881256 | Evaluation of induction potency of new drug candidates on CYP1A2 and CYP3A4 using real-time one-step RT-PCR in primary cultures of cryopreserved human hepatocytes. | 2009 |
2 |
| 22 |
16324277 | [The combined effect of isoniazid and rifampicin on the activities of CYP4501A2 and CYP4503A4 in primary hepatocytes from healthy human adults]. | 2005 Nov |
2 |
| 23 |
10673364 | Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR. | 2000 Jan 27 |
1 |
| 24 |
9454825 | Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isozymes in human hepatocytes in primary culture. | 1998 Feb |
1 |
| 25 |
9141435 | Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture. | 1997 May |
1 |
| 26 |
8843295 | Induction of theophylline clearance by rifampin and rifabutin in healthy male volunteers. | 1996 Aug |
2 |
| 27 |
7557864 | Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture. | 1995 Oct |
2 |
| 28 |
7585637 | Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. | 1995 Dec 1 |
1 |