18 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 29155491 | Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors. | 2018 Apr | 1 |
2 | 25159194 | Pomalidomide: evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects. | 2015 Feb | 1 |
3 | 23001793 | Stereoselective interaction between tetrahydropalmatine enantiomers and CYP enzymes in human liver microsomes. | 2013 Jan | 1 |
4 | 23434495 | Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. | 2013 Apr 15 | 1 |
5 | 22022918 | Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. | 2012 Mar | 1 |
6 | 22266842 | Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist. | 2012 Apr | 1 |
7 | 21277363 | Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes. | 2011 Apr 10 | 1 |
8 | 18950609 | Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1. | 2009 Apr 15 | 1 |
9 | 19843060 | In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation. | 2009 Oct | 1 |
10 | 18819885 | [Effect of ketoconazole on the activity of CYP4503A4 and CYP450 1A2 of hepatic microsomes in healthy adults]. | 2008 Aug | 3 |
11 | 17542019 | In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography. | 2007 Sep | 1 |
12 | 15618748 | In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazole. | 2003 | 1 |
13 | 9925971 | In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes. | 1999 Mar | 1 |
14 | 10078840 | Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential. | 1999 Jan | 1 |
15 | 10418968 | Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential. | 1999 Jun 1 | 1 |
16 | 9531525 | Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor. | 1998 Apr | 1 |
17 | 9384460 | The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine. | 1997 Nov | 1 |
18 | 8591723 | Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans. | 1995 Nov | 1 |