Hydrogen Peroxide

mitogen activated protein kinase 3 ; Rattus norvegicus







72 Article(s)
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1 34428890 The Protective Effect of Docosahexaenoic Acid on PC12 Cells in Oxidative Stress Induced by H2O2 through the TrkB-Erk1/2-CREB Pathway. 2021 Sep 15 2
2 33658932 Aspirin Eugenol Ester Protects Vascular Endothelium From Oxidative Injury by the Apoptosis Signal Regulating Kinase-1 Pathway. 2020 2
3 29404859 Serum Exosomes Attenuate H2O2-Induced Apoptosis in Rat H9C2 Cardiomyocytes via ERK1/2. 2019 Feb 1
4 30615921 Shengmai injection alleviates H2O2‑induced oxidative stress through activation of AKT and inhibition of ERK pathways in neonatal rat cardiomyocytes. 2019 Jul 15 1
5 30876692 Cardioprotective effects of constitutively active MEK1 against H2O2-induced apoptosis and autophagy in cardiomyocytes via the ERK1/2 signaling pathway. 2019 Apr 23 4
6 31030942 p22phox promotes Ang-II-induced vascular smooth muscle cell phenotypic switch by regulating KLF4 expression. 2019 Jun 18 3
7 31356907 Inhibitory effects of hydrogen on in vitro platelet activation and in vivo prevention of thrombosis formation. 2019 Sep 15 1
8 31655619 Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway. 2019 Oct 26 1
9 29052798 Curcumin pretreatment prevents hydrogen peroxide-induced oxidative stress through enhanced mitochondrial function and deactivation of Akt/Erk signaling pathways in rat bone marrow mesenchymal stem cells. 2018 Jun 1
10 28378219 Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts. 2017 May 1
11 28447781 Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage. 2017 Aug 16 1
12 29066484 Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line. 2017 Sep 1
13 27168176 Acute liver failure impairs function and expression of breast cancer-resistant protein (BCRP) at rat blood-brain barrier partly via ammonia-ROS-ERK1/2 activation. 2016 Jul 1
14 27444820 A Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons. 2016 Jul 22 1
15 25203460 Cardioprotective and cardiotoxic effects of quercetin and two of its in vivo metabolites on differentiated h9c2 cardiomyocytes. 2015 Feb 2
16 25380156 c-Src, ERK1/2 and Rho kinase mediate hydrogen peroxide-induced vascular contraction in hypertension: role of TXA2, NAD(P)H oxidase and mitochondria. 2015 Jan 4
17 25450615 Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription. 2015 Feb 1
18 26550832 The Protective Effect of INH2BP, a Novel PARP Inhibitor 5-Iodo-6-Amino-1,2-Benzopyrone, Against Hydrogen Peroxide-Induced Apoptosis Through ERK and p38 MAPK in H9c2 Cells. 2015 1
19 24607510 Cardioprotective effects of rhamnetin in H9c2 cardiomyoblast cells under H₂O₂-induced apoptosis. 2014 May 14 2
20 25128810 The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. 2014 Oct 1 2
21 25216715 GM1 ganglioside activates ERK1/2 and Akt downstream of Trk tyrosine kinase and protects PC12 cells against hydrogen peroxide toxicity. 2014 Nov 3
22 23667869 Α-tocopherol prevents ERK1/2 activation in PC12 cells under conditions of oxidative stress and its contribution to the protective effect. 2013 May 2
23 24049114 Exercise alters the regulation of myocardial Na(+)/H(+) exchanger-1 activity. 2013 Nov 15 5
24 22134701 Inhibition of ROS-activated ERK1/2 pathway contributes to the protection of H2S against chemical hypoxia-induced injury in H9c2 cells. 2012 Mar 2
25 22268112 Hydrogen peroxide enhances the expression of Giα proteins in aortic vascular smooth cells: role of growth factor receptor transactivation. 2012 Apr 15 3
26 22441302 Effects of purple grape juice in the redox-sensitive modulation of right ventricular remodeling in a pulmonary arterial hypertension model. 2012 Jul 1
27 23109870 α-Tocopherol at nanomolar concentration protects PC12 cells from hydrogen peroxide-induced death and modulates protein kinase activities. 2012 1
28 21094128 MAPK signaling in H9c2 cardiomyoblasts exposed to cholesterol secoaldehyde--role of hydrogen peroxide. 2011 Jan 7 2
29 21258655 Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms. 2011 1
30 21960664 3-(2,6-dimethylphenyl)-2-selenoxo-1,3-thiazolidin-4-one suppresses hydrogen peroxide-induced cytotoxicity on PC12 cells via activation of MAPK. 2011 Dec 1
31 22097737 [Effect of ERK1/2 signaling pathway on astragaloside IV protects H9c2 cells against H2O2-induced oxidative injury]. 2011 Aug 3
32 19787459 Involvement of ERK1/2 pathway in neuroprotection by salidroside against hydrogen peroxide-induced apoptotic cell death. 2010 Mar 3
33 19885844 Advanced glycation end-products activate extracellular signal-regulated kinase via the oxidative stress-EGF receptor pathway in renal fibroblasts. 2010 Jan 1 1
34 20302682 Quercetin, the active phenolic component in kiwifruit, prevents hydrogen peroxide-induced inhibition of gap-junction intercellular communication. 2010 Jul 4
35 20495008 Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells. 2010 Jul 30 2
36 20629637 MEK/ERK pathway mediates cytoprotection of salvianolic acid B against oxidative stress-induced apoptosis in rat bone marrow stem cells. 2010 Nov 3
37 20868529 The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons. 2010 Sep 27 4
38 18941904 Lanthanum chloride suppresses hydrogen peroxide-enhanced calcification in rat calcifying vascular cells. 2009 Apr 1
39 19059215 PKD prevents H2O2-induced apoptosis via NF-kappaB and p38 MAPK in RIE-1 cells. 2009 Jan 16 1
40 19362115 Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro. 2009 Jul 1
41 19720069 Differential regulation of the hydrogen-peroxide-induced inhibition of gap-junction intercellular communication by resveratrol and butylated hydroxyanisole. 2009 Dec 1 3
42 17965278 Oxidative stress and adenosine A1 receptor activation differentially modulate subcellular cardiomyocyte MAPKs. 2008 Jan 5
43 18272143 Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices. 2008 Mar 14 2
44 18410586 Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras. 2008 May 4
45 18668153 Involvement of ERK1/2 and p38 MAPK in up-regulation of 14-3-3 protein induced by hydrogen peroxide preconditioning in PC12 cells. 2008 Aug 1
46 18822160 Mitogenic and functional responses by nicotine and hydrogen peroxide in AR42J cells: a comparative study. 2008 Jul 31 1
47 17496232 Mitochondrial nitric oxide in the signaling of cell integrated responses. 2007 May 1
48 16362428 Pramipexole protects against H2O2-induced PC12 cell death. 2006 Jan 2
49 16883639 Samul extract protects against the H2O2-induced apoptosis of H9c2 cardiomyoblasts via activation of extracellular regulated kinases (Erk) 1/2. 2006 1
50 15703274 A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. 2005 Apr 1