Zinc

amyloid beta precursor protein ; Homo sapiens







136 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
101 17686982 Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity. 2007 Aug 14 1
102 17718543 Zinc lowers amyloid-beta toxicity by selectively precipitating aggregation intermediates. 2007 Sep 18 1
103 17983245 Zinc binding to amyloid-beta: isothermal titration calorimetry and Zn competition experiments with Zn sensors. 2007 Nov 27 9
104 18221229 Therapeutic treatment of Alzheimer's disease using metal complexing agents. 2007 Nov 2
105 16266835 Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease. 2006 Feb 5
106 16325427 Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease. 2006 Jul 1
107 16503166 Metal exposure and Alzheimer's pathogenesis. 2006 Jul 1
108 16648635 Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity. 2006 Jun 30 1
109 16678130 Selective destabilization of soluble amyloid beta oligomers by divalent metal ions. 2006 Jun 23 3
110 16766161 An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled beta-amyloid peptide fragments Abeta (31-35), Abeta (1-40) and Abeta (1-42). 2006 Jul 1 1
111 16848423 NMR reveals anomalous copper(II) binding to the amyloid Abeta peptide of Alzheimer's disease. 2006 Jul 26 5
112 17183156 Plasma amyloid-beta, Abeta1-42, load is reduced by haemodialysis. 2006 Dec 1
113 15593132 Metal-binding properties of the peptide APP170-188: a model of the ZnII-binding site of amyloid precursor protein (APP). 2005 Jan 21 1
114 15718230 Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide. 2005 Apr 22 1
115 16078307 Characterization of the ZnII binding to the peptide amyloid-beta1-16 linked to Alzheimer's disease. 2005 Sep 1
116 15582280 Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. 2004 Nov-Dec 1
117 12435742 Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid. 2003 Jan 31 1
118 14622293 Beta-amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH. 2003 Nov 1
119 12192006 Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). 2002 Oct 25 1
120 11274207 Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. 2001 Jun 8 2
121 11470313 Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases. 2001 May 15 1
122 10801774 Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. 2000 Jun 30 2
123 10801964 Alzheimer's disease, beta-amyloid protein and zinc. 2000 May 1
124 10194381 Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. 1999 Apr 6 1
125 10621945 Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease. 1999 Aug 2
126 9582309 Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. 1998 May 22 4
127 9667777 Copper, iron and zinc in Alzheimer's disease senile plaques. 1998 Jun 11 1
128 9924995 Aggregation of A beta Alzheimer's disease-related peptide studied by dynamic light scattering. 1998 Dec 1
129 9003194 Progress curve analysis of the kinetics with which blood coagulation factor XIa is inhibited by protease nexin-2. 1997 Jan 14 2
130 9202323 alpha2-Macroglobulin as a beta-amyloid peptide-binding plasma protein. 1997 Jul 1
131 8592145 Zinc-induced aggregation of human and rat beta-amyloid peptides in vitro. 1996 Feb 2
132 8592147 Aggregation and metal-binding properties of mutant forms of the amyloid A beta peptide of Alzheimer's disease. 1996 Feb 1
133 7778065 Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor. 1995 Apr 1 5
134 8588942 Characterization of the high affinity heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP) and its enhancement by zinc(II). 1995 Jul-Aug 1
135 8163520 Modulation of A beta adhesiveness and secretase site cleavage by zinc. 1994 Apr 22 3
136 8344894 A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease. 1993 Aug 5 1