Sirolimus

amyloid beta precursor protein ; Homo sapiens







11 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 35142986 Neuroprotective Effect of Lentivirus-Mediated FGF21 Gene Delivery in Experimental Alzheimer's Disease is Augmented when Concerted with Rapamycin. 2022 May 1
2 31176046 The neuroprotection of progesterone against Aβ-induced NLRP3-Caspase-1 inflammasome activation via enhancing autophagy in astrocytes. 2019 Sep 2
3 29395359 U1 small nuclear RNA overexpression implicates autophagic-lysosomal system associated with AD. 2018 Nov 1
4 27599716 Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis. 2016 Nov 1
5 24794719 Rapamycin protects against Aβ-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons. 2014 Sep 1
6 23121022 Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease. 2013 Mar 2
7 23305067 Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease. 2013 May 1 1
8 20178983 Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. 2010 Apr 23 4
9 20542014 Rapamycin promotes beta-amyloid production via ADAM-10 inhibition. 2010 Jul 30 2
10 19215663 Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions. 2009 Nov 1
11 16955484 The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide. 2006 Nov 1 1